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BGU researchers identify vitamin B12 as an effective canker sore therapy
February 10, 2009A team of physicians at Ben-Gurion University of the Negev has discovered that a nightly dose of vitamin B12 is a simple, effective and low risk therapy to prevent Recurrent Aphthous Stomatitis (RAS), better known as "canker sores."
According to lead researcher Dr. Ilia Volkov, "the frequency of RAS is as much as 25 percent in the general population, however, until now, there has been no optimal therapeutic approach."
The findings were reported in the January/February issue of the The Journal of the American Board of Family Medicine 22 (1): 9-16 (2009). Dr.Volkov is a primary care physician in the Clalit Health Services and lecturer in Ben-Gurion University's Department of Family Medicine in its Faculty of Health Sciences.
The researchers tested the effect of vitamin B12 on 58 randomly selected RAS patients who received either a dose of 1,000 mcg of B12 by mouth at bedtime or a placebo, and were tested monthly for six months. Approximately three quarters (74 percent) of the patients of the treated group and only a third (32 percent) of the control group achieved remission at the end of the study.
According to the research, "The average outbreak duration and the average number of ulcers per month decreased in both groups during the first four months of the trial. However, the duration of outbreaks, the number of ulcers, and the level of pain were reduced significantly at five and six months of treatment with vitamin B12, regardless of initial vitamin B12 levels in the blood. During the last month of treatment a significant number of participants in the intervention group reached 'no aphthous ulcers status' (74.1% vs 32.0%; P < .01)."
The treated patients expressed greater comfort, reported less pain, fewer ulcers, and shorter outbreaks during the six months while among the control group the average pain level decreased during the first half of the period but increased during the second half.
American Associates, Ben-Gurion University of the Negev
The researchers tested the effect of vitamin B12 on 58 randomly selected RAS patients who received either a dose of 1,000 mcg of B12 by mouth at bedtime or a placebo, and were tested monthly for six months. Approximately three quarters (74 percent) of the patients of the treated group and only a third (32 percent) of the control group achieved remission at the end of the study.
According to the research, "The average outbreak duration and the average number of ulcers per month decreased in both groups during the first four months of the trial. However, the duration of outbreaks, the number of ulcers, and the level of pain were reduced significantly at five and six months of treatment with vitamin B12, regardless of initial vitamin B12 levels in the blood. During the last month of treatment a significant number of participants in the intervention group reached 'no aphthous ulcers status' (74.1% vs 32.0%; P < .01)."
The treated patients expressed greater comfort, reported less pain, fewer ulcers, and shorter outbreaks during the six months while among the control group the average pain level decreased during the first half of the period but increased during the second half.
American Associates, Ben-Gurion University of the Negev
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University of Utah School of Medicine researchers have developed a new tool that facilitates diagnosis of anemia related to chronic illness, as well as diseases of iron overload. The results of a study detailing the new tool are published in the August 2008 issue of the journal Cell Metabolism, a publication of Cell Press.
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Source Naturals B-12 Sublingual, 2000 mcg, Tablets, 100 tablets (Pack of 3) by Source Naturals Vitamin supplement. Vitamin B-12 is an essential nutrient, involved in protein formation. The coenzyme form of Vitamin B-12 is necessary for carbohydrate, protein and fat metabolism, as well as for proper DNA replication. Source Naturals Vitamin B-12 tabl |
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Sublingual Vitamin B12 (1000 mcg), B6 (5mg), Folic Acid(400 mcg) & Biotin (25mcg) - 250 Sublingual Tablets - Formulated with methylcobalamin Vitamin B-12. by Wonder Laboratories You may have heard it over your years, Doctors giving your mom, dad, brother, aunt or friend B12 injection to fight anemia, generally poor health and to increase energy levels. Well now you can get that same boost from Sublingual B12 in tablet form. Produced, Packaged and Sold by Wonder Laboratories, OUR ADVANCED B-12 is specially formulated with methylcobalamin Vitamin B-12. Methylcobalamin is a type of Vitamin B12. Vitamin B12 comes in several kinds including hydroxy-, cyano-, and adenosyl-, but only the methyl form is also used in the central nervous system. Deficiency states are fairly common and vitamin B12 deficiency mimics many other disease states of a neurological or psychological kind, and it causes anemia. Cyanocobalamin (the cheapest to produce and the kind in most vitamin... |
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Vitamin B-12 500 mcg 100 Caps by Swanson Premium Brand The vitamin for vascular health, vim, and vigor! Vitamin B-12 is commonly associated with energy because it plays a vital role in the formation of the red blood cells that deliver oxygen to all parts of the body. It also supports cardiovascular health by working with vitamin B-6 and folic acid to help control harmful homocysteine. While adequate B-12 intake is important for everyone, supplementation may be particularly helpful for some people because the vitamin is found primarily in animal-based foods. |
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Source Naturals Methylcobalamin, Vitamin B-12, Cherry Flavored Sublingual, Tablets, 120 tablets by Source Naturals Dietary supplement. Methylcobalamin, an active coenzyme form of vitamin B-12 is essential for cell growth and replication. It is more concentrated than other forms of B-12 in the cerebral spinal fluid where it can be used by the central nervous system. It donates methyl groups to the myelin sheath that insulates certain nerve fibers. It may also play a role in maintaining a healthy sleep-wake cycle, as well as normal nerve function. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.) Suitable for vegetarians. Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives or artificial color, flavor or fragrance. |
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TwinLab B-12 Dots Vitamin B-12 Tablets, 5000 mcg, 60-Count Bottles (Pack of 2) by Twinlab B12 Dots are specially formulated tiny sublingual B12 tablets. One dot (sublingual tablet) contains 500 mcg of Vitamin B12. Each dot quickly dissolves for maximum absorption of Vitamin B12. Delicious 100-percent natural cherry flavor and sugar and gelatin |
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