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Obesity linked to hormone imbalance that impacts sexual quality of life
March 03, 2009Weight loss through gastric bypass surgery can reverse hormonal changes
Hormonal changes and diminished sexual quality of life among obese men are related to the degree of obesity, and both are improved after gastric bypass surgery according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
"Previous studies have found that obesity is correlated to lower sperm count and can be associated with infertility, but we wanted to know if obesity was biologically associated with an unsatisfying sex life, and if so, could it be reversible," said Dr. Ahmad Hammoud, MD, of the University of Utah and lead author of the study. "Our results show that the answer to both questions may be yes."
For this study, researchers followed 64 men over two years who participated in the Utah Obesity Study, which investigated the two-year morbidity of severely obese men undergoing Roux-en-Y gastric bypass surgery compared to controls. Researchers measured weight, BMI (body mass index) and reproductive hormone levels of participants at the beginning of the study and once more two years later. Similarly subjects completed a questionnaire designed to assess the impact of weight on quality of life in obese individuals at the onset of the study and again two years later.
"In our study population, we found that lower testosterone levels and diminished ratings for sexual quality of life were correlated with increased BMI," said Dr. Hammoud. "Subjects who lost weight through bariatric surgery experienced a reduction in estradiol levels, an increase in testosterone levels and an increase in ratings of sexual quality of life."
Dr. Hammoud points out that results from this study highlight an association between sexual quality of life and hormonal measures independent from weight. Because this relationship is confounded by biopsychosocial aspects of obesity, further studies are required to determine a cause and effect relationship.
The Endocrine Society
For this study, researchers followed 64 men over two years who participated in the Utah Obesity Study, which investigated the two-year morbidity of severely obese men undergoing Roux-en-Y gastric bypass surgery compared to controls. Researchers measured weight, BMI (body mass index) and reproductive hormone levels of participants at the beginning of the study and once more two years later. Similarly subjects completed a questionnaire designed to assess the impact of weight on quality of life in obese individuals at the onset of the study and again two years later.
"In our study population, we found that lower testosterone levels and diminished ratings for sexual quality of life were correlated with increased BMI," said Dr. Hammoud. "Subjects who lost weight through bariatric surgery experienced a reduction in estradiol levels, an increase in testosterone levels and an increase in ratings of sexual quality of life."
Dr. Hammoud points out that results from this study highlight an association between sexual quality of life and hormonal measures independent from weight. Because this relationship is confounded by biopsychosocial aspects of obesity, further studies are required to determine a cause and effect relationship.
The Endocrine Society
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School-based physical education plays a key role in curbing obesity and improving fitness among adolescents from low-income communities, according to a new study led by researchers at the University of California, San Francisco and UC Berkeley.
Energy gap useful tool for successful weight loss maintenance strategy
Americans continue to get heavier. Most weight control methods short of bariatric surgery are generally considered ineffective in preventing obesity or reducing weight.
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American Dietetic Association Releases Updated Position Paper Promoting and Supporting Breastfeeding
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Addressing obesity via the 'energy gap'
The November issue of the Journal of the American Dietetic Association features a commentary by James O. Hill, an honorary ADA member, professor of pediatrics and medicine and director of the Center for Human Nutrition at the University of Colorado-Denver.
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Study: Lap band surgery effective for morbidly obese children
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Gastroenterology/hepatology societies release report evaluating fellowship training curriculum
Due to the increasing complexities of treating digestive diseases, allowing gastroenterological (GI) trainee physicians the opportunity to develop enhanced abilities and experiences in specific disease areas or procedures will be a great benefit to patients, according to a "Report of the Multisociety Task Force on GI Training."
Study finds link between childhood physical abuse and arthritis
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