Therapeutic hypothermia is promising strategy to minimize tissue damageMarch 20, 2009Recognition of the benefits of cooling strategies to protect the brain and spinal cord after traumatic injury has led to a wealth of cutting edge research, prime examples of which are featured in a special hypothermia issue of Journal of Neurotrauma, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The issue will be available free online at www.liebertpub.com/neu The issue includes a series of original articles presenting experimental and clinical evidence to support the use of modest hypothermia in specific conditions. These reports emanated from presentations at the 2nd International Brain Hypothermia Symposium and were selected for publication in the Journal by Guest Editors W. Dalton Dietrich, PhD, and M. Ross Bullock, MD, PhD, both from the University of Miami Miller School of Medicine and Patrick M. Kochanek, MD, from the University of Pittsburgh. In his Introduction, Dr. Dietrich points out that many factors determine whether hypothermic therapy will be beneficial, including "how early hypothermic therapy is initiated after the insult, the duration of the hypothermic period, the degree of hypothermia, as well as the rewarming protocol. Thus, it is important that basic research studies are continuing in clinical relevant animal models to address these important questions." The issue explores several aspects of hypothermia, including studies in animal models, its use in the operating room, and its role in the treatment of cardiac arrest, stroke and subarachnoid hemorrhage, traumatic brain (TBI) and spinal cord injury, and pediatric TBI and asphyxia. Mackensen et al. focus on "Perioperative Hypothermia: Use and Therapeutic Implications," and Kim et al. describe "The Use of Pre-Hospital Mild Hypothermia After Resuscitation from Out-of-Hospital Cardiac Arrest." Kochanek et al. collaborate on two articles on therapeutic hypothermia in pediatric populations, one describing the Safar Vision, and the other focusing on applications in pediatric cardiac arrest. Shankaran presents "Neonatal Encephalopathy: Treatment with Hypothermia," and Bullock et al. provides an overview of "Current and Future Role of Therapeutic Hypothermia." Mary Ann Liebert, Inc./Genetic Engineering News |
|||||||||||||||||||||
| Related Hypothermia Current Events and Hypothermia News Articles Scripps research scientists find new link between insulin and core body temperature A team led by scientists at The Scripps Research Institute have discovered a direct link between insulin-a hormone long associated with metabolism and metabolic disorders such as diabetes-and core body temperature. Brain injured athletes may benefit from hypothermia research NFL players and other athletes who suffer serious or multiple concussions may benefit from ground-breaking research being conducted by scientists at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center. The scientists are developing a surgical technique that involves hypothermia in specific regions of the brain. Global death toll: 1 million premature babies every year More than one million infants die each year because they are born too early, according to the just released White Paper, The Global and Regional Toll of Preterm Birth. Cooling treatment after cardiac arrest is cost-effective, Penn study shows A brain-preserving cooling treatment called therapeutic hypothermia is a cost-effective way to improve outcomes after out-of-hospital cardiac arrest, which claims the lives of more than 300,000 people each year in the United States and leaves thousands of others neurologically devastated. Coronary angiography may improve outcomes for cardiac arrest patients People who suffer cardiac arrests and then receive coronary angiography are twice as likely to survive without significant brain damage compared with those who don't have the procedure, according to a study by University of Pittsburgh School of Medicine researchers. Anesthesia or hypothermia: Warning for Alzheimer's patients Everyone knows that its important to keep a cool head, but a new study published online in The FASEB Journal shows that for Alzheimer's patients, a cool head may make the disease worse. Anesthesia is found to induce hyperphosphorylation of tau at sites related to Alzheimer's disease Scientists from The New York State Office of Mental Retardation and Developmental Disabilities' (OMRDD) New York State Institute for Basic Research in Developmental Disabilities (IBR) report today in the March 2009 issue of the Journal of Alzheimer's Disease that anesthesia induces phosphorylation of tau. Penn study: Chances of surviving cardiac arrest depend on where patients are treated Efforts to fight the toll of cardiac arrest have typically focused on pre-hospital factors -- bystander CPR education and improvement, public defibrillation programs, and quicker EMS response. But new research from the University of Pennsylvania School of Medicine reveals that the hospital where patients are cared for after being resuscitated plays a key role in their chances of survival following these incidents, which takes the lives of more than 300,000 Americans each year. Preterm births rise 36 percent since early 1980s New government statistics confirm that the decades-long rise in the United States preterm birth rate continues, putting more infants than ever at increased risk of death and disability. Research team explores causes of death on Mount Everest An international research team led by Massachusetts General Hospital (MGH) investigators has conducted the first detailed analysis of deaths during expeditions to the summit of Mt. Everest. More Hypothermia Current Events and Hypothermia News Articles |
|||||||||||||||||||||
|
|||||||||||||||||||||
|
|||||||||||||||||||||