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Drug commonly used for alcoholism, drug addiction, curbs urges of compulsive stealers
April 01, 2009It appears that a drug commonly used to treat alcohol and drug addiction has a similar effect on the compulsive behavior of kleptomaniacs - it curbs their urge to steal, according to new research at the University of Minnesota.
The Medical School's Department of Psychiatry conducted an eight-week, double-blind study of 25 men and women ages 17-75, who spent an average of at least one hour a week stealing. Those who took the drug Naltrexone (mean dose of 117mg/day) reported significantly greater decline in stealing behavior compared to those taking placebo.
"It gets rid of that rush and desire," said Jon Grant, M.D., J.D., M.P.H., a University of Minnesota associate professor of psychiatry and principal investigator of the study. "The difference in their behavior was significant, and these people were really troubled by their behavior."
A recent, large epidemiological study of about 43,000 adults found that more than 11 percent of the general population admitted to having shoplifted in their lifetime. It is unclear, however, how many people who steal suffer from kleptomania.
While the drug is not a cure for kleptomania, Grant said it offers hope to those who are suffering from the addiction. He also said the drug would most likely work best in combination with individual therapy.
"These are people who steal even though they can easily afford not to," Grant said.
University of Minnesota
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Stress-induced changes in brain circuitry linked to cocaine relapse
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Research shows temptation more powerful than individuals realize
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Rutgers Research: Parkinson's Disease Alters Patient's Ability to Learn from Rewards while Treatment Affects Ability to Learn from Negative Outcomes
A new neuropsychological memory test is helping to uncover how Parkinson's disease can alter people's ability to learn about the consequences of the choices they make.
Site for alcohol's action in the brain discovered
lcohol's inebriating effects are familiar to everyone. But the molecular details of alcohol's impact on brain activity remain a mystery.
Insomniac flies resemble sleep-deprived humans
Researchers at Washington University School of Medicine in St. Louis have created a line of fruit flies that may someday help shed light on the mechanisms that cause insomnia in humans.
Flipping the brain's addiction switch without drugs
When someone becomes dependent on drugs or alcohol, the brain's pleasure center gets hijacked, disrupting the normal functioning of its reward circuitry.
Cocaine-linked genes enhance behavioral effects of addiction
New research sheds light on how cocaine regulates gene expression in a crucial reward region of the brain to elicit long-lasting changes in behavior.
Brain protein central to both Parkinson's, drug addiction identified
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