New minimally invasive surgery option for patients with stomach cancerApril 16, 2009A novel, minimally invasive surgical approach to treat stomach cancer has been shown to have advantages that may make it a preferable treatment for some patients. A new study led by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) compares traditional "open" surgery to remove the stomach with laparoscopic gastrectomy -- a minimally invasive procedure in which the surgeon removes the stomach while guided by a magnified image projected by a thin, lighted tube with a video camera at its tip, called a laparoscope. The findings demonstrate that while laparoscopic surgeries generally took longer to perform than open procedures, the minimally invasive approach yielded shorter hospital stays, decreased need for postoperative pain relief, fewer complications after surgery, and similar rates of recurrence-free survival after 36 months of follow-up. "Our number one goal in treating patients with stomach cancer is to remove the cancer completely and safely, while preserving his or her quality of life," says the study's lead author Vivian E. Strong, MD, a surgeon at MSKCC who specializes in laparoscopic surgery for the treatment of stomach cancer, also known as gastric cancer. "Laparoscopic gastrectomy is an excellent option for certain patients with the disease, and for those patients, this approach has the same success rate as standard open surgery, with significantly fewer complications." Published online in the Annals of Surgical Oncology, the paper describes the largest US study of laparoscopic gastrectomy to date and demonstrates both the safety and efficacy of the procedure. The study examined the surgical characteristics and oncologic outcomes of 30 patients who underwent laparoscopic gastrectomy and compared them to 30 patients who had open gastrectomies. The patients in each group were matched for cancer stage, age, and gender, and had their surgeries during the same time period. In addition to the benefits seen among the patients who underwent laparoscopic gastrectomy, researchers also observed that this approach enabled adequate lymph node retrieval, an important part of a complete cancer surgery in which nearby nodes are removed and then carefully examined for the presence of cancer cells to determine whether the cancer has spread. According to the authors, this finding addresses an ongoing controversy that questions whether removal of the lymph nodes and other oncologic features of the resection during laparoscopic gastrectomy are equivalent to open surgery, particularly given the technical demands of the minimally invasive approach and the learning curve required to perform an adequate resection. "Laparoscopic gastrectomy is a technically advanced surgical procedure," Dr. Strong notes. "Patients considering it should go to hospitals with a high volume of gastric cancer cases, and choose a surgeon who has extensive experience performing the laparoscopic procedure." MSKCC is one of the few National Cancer Institute--designated cancer centers with a specific program in treating cancers of the upper gastrointestinal tract, which includes the stomach. About 100 gastrectomies, both open and laparoscopic, are performed each year at MSKCC -- one of the highest volumes of surgery for this relatively rare cancer of any center in the country. The first laparoscopic gastrectomy performed at MSKCC was in 2001, and since 2005 more than 75 patients have had their stomach cancers treated laparoscopically. Despite the fact that each year approximately 22,000 Americans are diagnosed with stomach cancer, surgeons in the US have much less experience with laparoscopic gastrectomy than those in Korea and Japan, where many more cases of gastric cancer are treated and larger studies have been published demonstrating it to be a safe, effective, and well-accepted technique. Memorial Sloan-Kettering Cancer Center |
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| Related Stomach Cancer Current Events and Stomach Cancer News Articles Uncovering the secrets of ulcer-causing bacteria A team of researchers from Boston University, Harvard Medical School and Massachusetts Institute of Technology recently made a discovery that changes a long held paradigm about how bacteria move through soft gels. What are factors associated with use of gastric cancer screening services in Korea? The mortality of gastric cancer is decreasing despite the increasing incidence in Korea. This can be explained by surgical technique development and early detection by endoscopic screening or upper gastrointestinal study. Heavy drinkers face significantly increased cancer risk Heavy drinkers of beer and spirits face a much higher risk of developing cancer than the population at large, says a group of Montreal epidemiologists and cancer researchers. Simple measures may prevent transmission of stomach ulcer bacteria The stomach ulcer bacterium Helicobacter pylori is not transmitted through drinking water as previously thought, but rather through vomit and possibly faeces. Columbia team finds that gastrin plays significant role in helicobacter-induced stomach cancer A group led by Columbia University Medical Center's Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach. Tummy troubles -- gastrin key in bacterial-induced stomach cancer Current research suggests that levels of gastrin play a key role in the development of Helicobacter-induced stomach cancer. Glutamine supplements show promise in treating stomach ulcers Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Novel therapy may prove effective in treatment of 30 percent of cancers A ground-breaking Canada-wide clinical trial led by Dr. Katherine Borden, at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, has shown that a common anti-viral drug, ribavirin, can be beneficial in the treatment of cancer patients. Broccoli sprouts may prevent stomach cancer by defeating Helicobacter pylori Three-day-old broccoli sprouts, a widely available human food, suppressed Helicobacter pylori (H. pylori) infections, according to a report in Cancer Prevention Research, a journal of the American Association for Cancer Research. H. pylori infections are one of the most common bacterial infections worldwide and are a major cause of stomach cancer. Gutsy germs succumb to baby broccoli A small, pilot study in 50 people in Japan suggests that eating two and a half ounces of broccoli sprouts daily for two months may confer some protection against a rampant stomach bug that causes gastritis, ulcers and even stomach cancer. More Stomach Cancer Current Events and Stomach Cancer News Articles |
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