New topical spray may treat premature ejaculationApril 27, 2009PSD502, a new topical spray, is a safe and effective treatment for premature ejaculation. Researchers presented data on the spray's efficacy during a presentation of their randomized, Phase 3, double-blind, placebo-controlled study at the 104th Annual Scientific Meeting of the American Urological Association (AUA). One current treatment for premature ejaculation consists of topical creams with desensitizing agents which dull the penile skin and delay ejaculation. Although effective, these creams require use of a condom and/or washing the cream away before intercourse and they may reduce sexual pleasure. Researchers have shown that a new topical spray, consisting of an aerosol formulation of lidocaine and prilocaine, is effective and easy to use. It selectively desensitizes penile skin, affecting only the non-keratinized skin (the inner lining of the foreskin and the surface of the glans), without adversely affecting the sensation of ejaculation. This new treatment can be applied five minutes prior to intercourse. A total of 300 men with premature ejaculation, diagnosed using the International Society of Sexual Medicine's definition (intravaginal ejaculatory latency time of a minute or less), participated in this study. The participants were divided into two groups, one applied the PSD502 spray and the other applied a placebo spray five minutes prior to sexual intercourse. Both groups had an average baseline of 0.6 minutes latency time before ejaculation. After treatment, the PSD502 group improved to a latency time of four minutes; the placebo group only improved to one minute. The spray was well tolerated by both patients and partners, with no systemic or serious adverse events reported. Only 2.6 percent of the PSD502 group reported any treatment-related adverse events, compared to 1 percent of the placebo group. "Premature ejaculation is one of the most common sexual dysfunctions in men. It occurs in 20-30% of men of all ages and we need an effective, patient-friendly treatment for this distressing problem," said Ira D. Sharlip, MD, an AUA spokesman. "This new topical spray has promise to become one of the most effective treatments for premature ejaculation. It has a number of characteristics which will be attractive to patients with premature ejaculation." American Urological Association |
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| Related Premature Ejaculation Current Events and Premature Ejaculation News Articles Pivotal study for PSD502 -- the first potential treatment for premature ejaculation At the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE)., today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE). A genetic link to premature ejaculation Premature ejaculation can be embarrassing, but a new study suggests that it might be a genetic disorder. Male circumcision efforts lag in Africa despite evidence of dramatic impact in preventing HIV With millions of lives at stake over the next two decades, researchers and advocates at the AIDS 2008 Conference today called on the global health community to ramp up male circumcision to significantly reduce risk of HIV infection in Africa, and to move quickly to integrate the life-saving procedure into other comprehensive efforts to prevent transmission of the disease in the vulnerable nations of eastern and southern Africa. It's Not All in Your Head Researchers Conduct First Large Study Defining Premature Ejaculation by Stopwatch & Patient Reported Outcomes Future Pill for Premature Ejaculation a Success in Trials A new tablet could hold the key for men who suffer premature ejaculation, reports Marina Murphy in Chemistry & Industry Magazine. Trials by a US company have shown the pill, compound LI 301, to have an effect on everyone tested. Trials suggest the drug starts working within two hours, so it could be taken on an as-needed basis. Currently, there are no approved treatments for premature ejaculation. There is no definite date set for the release of LI 301 although some estimates suggest it could be available as soon as 2007. Other compounds being investigated for premature ejaculation are producing mixed results, but the new pill works in a different and unique way. It is thought that its succe More Premature Ejaculation Current Events and Premature Ejaculation News Articles |
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