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First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal
May 28, 2009New guidelines designed to standardize and optimize the diagnosis, treatment, and monitoring of patients with Medullary Thyroid Carcinoma (MTC), an uncommon and challenging form of thyroid cancer, have been developed by the American Thyroid Association and published online ahead of print in Thyroid, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The guidelines are available free online at www.liebertpub.com/thy
"Following careful peer review, Thyroid has published the first comprehensive set of clinical guidelines for the treatment of all medullary thyroid carcinoma (MTC) disorders," says Charles H. Emerson, MD, Editor-in-Chief of the Journal and Professor Emeritus at University of Massachusetts Medical School, in Worcester. "This form of thyroid cancer is especially important because of its high mortality, strong inheritance patterns, and associations with other serious glandular disorders. These evidence-based guidelines will become a benchmark for patient management and clinical research, as they illuminate the diagnostic and therapeutic strategies required when caring for gravely ill patients and those in the anxiety-ridden early stages of the disease, and when offering testing and counseling to family members."
MTC is a complex disease that accounts for about 4% of all thyroid cancer cases in the United States. Nearly 25% of cases worldwide are familial and present as an autosomal inherited disorder. In individuals with the inherited form of MTC, a preneoplastic lesion called C-cell hyperplasia will first develop and then progress to an invasive, life-threatening malignancy.
The American Thyroid Association (www.thyroid.org) has compiled 122 evidence-based recommendations that cover a range of clinical topics, including diagnosis and therapy for early disease, genetic testing, surgical management, post-surgical treatment and monitoring, management of persistent or recurrent MTC and metastatic disease, and long-term follow-up. The guidelines also propose directions for future research on MTC.
"Medullary thyroid cancer is a rare and fascinating disease that few health care professionals ever master," says Richard T. Kloos, MD, Chair of the ATA Guidelines Task Force, Secretary and Chief Operating Officer of the American Thyroid Association, and Co-Director of the Ohio State University Thyroid Cancer Unit. "The ATA guidelines promote optimal medical care that is grounded in an evidence-based review of the literature by an international and multidisciplinary panel. It is our hope that they will serve all the professionals that care for these patients, including those in the fields of endocrinology, genetics, pediatrics, radiology, nuclear medicine, surgery, and oncology."
Mary Ann Liebert, Inc./Genetic Engineering News
The American Thyroid Association (www.thyroid.org) has compiled 122 evidence-based recommendations that cover a range of clinical topics, including diagnosis and therapy for early disease, genetic testing, surgical management, post-surgical treatment and monitoring, management of persistent or recurrent MTC and metastatic disease, and long-term follow-up. The guidelines also propose directions for future research on MTC.
"Medullary thyroid cancer is a rare and fascinating disease that few health care professionals ever master," says Richard T. Kloos, MD, Chair of the ATA Guidelines Task Force, Secretary and Chief Operating Officer of the American Thyroid Association, and Co-Director of the Ohio State University Thyroid Cancer Unit. "The ATA guidelines promote optimal medical care that is grounded in an evidence-based review of the literature by an international and multidisciplinary panel. It is our hope that they will serve all the professionals that care for these patients, including those in the fields of endocrinology, genetics, pediatrics, radiology, nuclear medicine, surgery, and oncology."
Mary Ann Liebert, Inc./Genetic Engineering News
Thyroid Current Events and Thyroid News RSSNewly revised guidelines for managing thyroid cancer published in Thyroid journal
The American Thyroid Association has released new, revised Management Guidelines for the diagnosis and treatment of patients with thyroid nodules and thyroid cancer.
Researchers use drug-radiation combo to eradicate lung cancer
Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.
Study examines complications of thyroid surgery in older patients
In a study of patients undergoing thyroid surgery performed by a single surgeon, older adults did not appear to have more complications than younger patients.
Thyroid surgery safe for older patients, study finds
Thyroid surgery is safe for older patients, say physicians who found only slight differences in rates of complications and hospital readmissions in a multi-year study.
Can social networking help consumers get healthier?
Can social networking sites help people make wise health decisions? A new study in the Journal of Consumer Research says it depend on people's willingness to take action on the information they gain from the sites.
Novel, soy-based SE5-OH containing Natural S-equol supplement reduced hot flash frequency by nearly 59 percent
SE5-OH containing Natural S-equol, a novel soy germ-based ingredient in a supplement, improved menopausal symptoms, including significantly reducing hot flash frequency by nearly 59 percent, according to a peer-reviewed study in Japanese women.
Stem cell success points to way to regenerate parathyroid glands
An early laboratory success is taking University of Michigan researchers a step closer to parathyroid gland transplants that could one day prevent a currently untreatable form of bone loss associated with thyroid surgery.
New genetic link between cardiac arrhythmias and thyroid dysfunction identified
Genes previously known to be essential to the coordinated, rhythmic electrical activity of cardiac muscle -- a healthy heartbeat -- have now also been found to play a key role in thyroid hormone (TH) biosynthesis, according to Weill Cornell Medical College researchers.
Water quality in orbit
Space is not a fun place to get a stomach bug. To ensure drinking water is adequately disinfected, University of Utah chemists developed a two-minute water quality monitoring method that just started six months of tests aboard the International Space Station.
How to Make a Lung: Cell-Regeneration Molecules Essential Signals for Early Lung Development, Penn Study Finds
A tissue-repair-and-regeneration pathway in the human body, including wound healing, is essential for the early lung to develop properly.
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