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GEN reports on efforts to quickly develop swine flu vaccine
June 03, 2009Scientists around the world are accelerating their efforts to develop a vaccine against the H1N1 influenza virus (Swine flu) as rapidly as possible, reports Genetic Engineering & Biotechnology News (GEN). The need for such a vaccine received a strong impetus from the World Health Organization, which has issued a Phase 5 pandemic alert, a strong signal that the WHO believes a pandemic is imminent, according to the June 1 issue of GEN (www.genengnews.com/articles/chitem.aspx?aid=2938).
"It can take five or six months to come up with an entirely novel influenza vaccine," says John Sterling, Editor in Chief of GEN. "There is a great deal of hope that biotech and pharma companies might be able to have something ready sooner."
One company, Replikins, actually predicted over a year ago that significant outbreaks of the H1N1 flu virus would occur within 6-12 months. The predictions were based on correlations of flu virus specimens and PubMed documentation of major outbreaks during the past 90 years, focusing on concentrations of, and spacings between, replikins-the lysine and histidine residues in the hemagglutinin (HA) unit genetic sequences of the eight major genes in the influenza virus. Replikins' officials say the company's PanFLu™ vaccine is ready for clinical trials.
Novavax plans to create a virus-like particle-based (VLP) vaccine against the H1N1 strain, which obviates the need for a live virus seed for manufacturing. The VLPs contain the proteins that make the virus' outer shell and the surface proteins, without the RNA required for replication.
Mary Ann Liebert, Inc./Genetic Engineering News
Novavax plans to create a virus-like particle-based (VLP) vaccine against the H1N1 strain, which obviates the need for a live virus seed for manufacturing. The VLPs contain the proteins that make the virus' outer shell and the surface proteins, without the RNA required for replication.
Mary Ann Liebert, Inc./Genetic Engineering News
Vaccine Current Events and Vaccine News RSSCommon Pain Relievers May Dilute Power of Flu Shots
With flu vaccination season in full swing, research from the University of Rochester Medical Center cautions that use of many common pain killers - Advil, Tylenol, aspirin - at the time of injection may blunt the effect of the shot and have a negative effect on the immune system.
PMH finding may help some tonsil cancer patients avoid chemotherapy
Clinical researchers at Princess Margaret Hospital (PMH) have confirmed that patients with oropharyngeal squamous cell cancer ("tonsil cancer") harbour a common type of human papilloma virus (HPV16), but also that such cancers are very sensitive to radiation.
PATH Malaria Vaccine Initiative shares strategy for developing 'next-generation' malaria vaccines
Marking its tenth anniversary year, the PATH Malaria Vaccine Initiative (MVI) today unveiled a new strategy that sets the stage for an aggressive push targeting the long-term goal of eliminating and eradicating malaria. Malaria is one of the world's deadliest infectious diseases, killing nearly 900,000 people a year, most of them children in sub-Saharan Africa.
Study reveals a 'missing link' in immune response to disease
The immune system's T cells have the unique responsibilities of being both jury and executioner. They examine other cells for signs of disease, including cancers or infections, and, if such evidence is found, rid them from the body. Precisely how T cells shift so swiftly from one role to another, however, has been a mystery.
Sneezing in times of a flu pandemic
The swine flu (H1N1) pandemic has received extensive media coverage this year. The World Health Organization, in addition to providing frequent updates about cases of infection and death tolls, recommends hyper vigilance in daily hygiene such as frequent hand washing or sneezing into the crook of our arms.
Pitt, US Army team designs new strategy to find drugs to treat neglected infection
Using an unconventional approach that they designed, University of Pittsburgh drug discoverers and their collaborators at Walter Reed Army Institute of Research have identified compounds that hold promise for treating leishmaniasis, a parasitic infection that many consider one of the world's most overlooked diseases.
Initial Results Show Pregnant Women Mount Strong Immune Response To One Dose of 2009 H1N1 Flu Vaccine
Healthy pregnant women mount a robust immune response following just one dose of 2009 H1N1 influenza vaccine, according to initial results from an ongoing clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health.
Flu vaccine given to women during pregnancy keeps infants out of the hospital
Infants born to women who received influenza vaccine during pregnancy were hospitalized at a lower rate than infants born to unvaccinated mothers.
Global challenges and opportunities in fighting HIV/AIDS and neglected diseases
Responding to the HIV/AIDS pandemic and tackling so-called neglected tropical diseases are the focus of the November/December 2009 edition of Health Affairs.
Progress made on group B streptococcus vaccine
Scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have completed a Phase II clinical study that indicates a vaccine to prevent Group B Streptococcus (GBS) infection is possible.
More Vaccine Current Events and Vaccine News Articles
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The Vaccine Book: Making the Right Decision for Your Child (Sears Parenting Library) by Robert Sears (Author) With the spate of publicity surrounding the possible health risks posed by childhood immunization, parents are no longer simply following doctor's orders and automatically having their children vaccinated. Instead, they are asking questions. The problem is the search for answers only leads parents to conflicting, one-sided information: doctors claim that parents are endangering their child's life if they refuse shots, while radical vaccine opponents claim parents are endangering their child's life if they accept shots. With THE VACCINE BOOK, parents finally have one, fair, impartial, fact-based resource they can turn to for answers. Each chapter is devoted to a disease/vaccine pair and offer a comprehensive discussion of what the disease is, how common or rare it is, how serious or... |
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Vaccine: The Controversial Story of Medicine's Greatest Lifesaver by Arthur Allen (Author) "A timely, fair-minded and crisply written account."—New York Times Book Review Vaccine juxtaposes the stories of brilliant scientists with the industry's struggle to produce safe, effective, and profitable vaccines. It focuses on the role of military and medical authority in the introduction of vaccines and looks at why some parents have resisted this authority. Political and social intrigue have often accompanied vaccination—from the divisive introduction of smallpox inoculation in colonial Boston to the 9,000 lawsuits recently filed by parents convinced that vaccines caused their children's autism. With narrative grace and investigative journalism, Arthur Allen reveals a history illuminated by hope and shrouded by controversy, and he sheds new light on changing... |
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What Your Doctor May Not Tell You About Children's Vaccinations by Stephanie Cave (Author), Deborah Mitchell (Contributor) In this book, Dr. Stephanie Cave explains vaccinationsthe pros and the cons. With detailed facts about each vaccination, as well as regulations and laws, this book provides easily understandable information to help parents make a knowledgeable, responsible choice about vaccinating their children. |
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Vaccines: What CDC Documents and Science Reveal Starring: DO Sherri J. Tenpenny |
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Vaccine Safety Manual for Concerned Families and Health Practitioners: Guide to Immunization Risks and Protection by Neil Z. Miller (Author), Russell, M.D. Blaylock (Foreword) [This earlier edition is now out-of-print. It has been replaced with the new, updated 2nd edition of Vaccine Safety Manual, ISBN: 978-1881217374.] The Vaccine Safety Manual is the world's most complete guide to immunization risks and protection. It includes pertinent information on every major vaccine: polio, tetanus, MMR, hepatitis A, B, HPV (cervical cancer), Hib, Flu, chickenpox, shingles, rotavirus, pneumococcal, meningococcal, RSV, DTaP, anthrax, smallpox, TB, and more. All of the information, including detailed vaccine safety and efficacy data, is written in an easy-to-understand format, yet includes more than 1,000 scientific citations. More than 90 charts, graphs and illustrations supplement the text. This encyclopedic health manual is an important addition to every family's home... |
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Vaccines: Expert Consult (Expert Consult Title: Online + Print) by Stanley A. Plotkin MD (Author), Walter A. Orenstein MD (Author), Paul A. Offit MD (Author) Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety.recommendations for vaccine use, with rationales.data on the impact of vaccination programs on morbidity and mortality.and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing... |
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Vaccines: Are They Really Safe and Effective by Neil Z. Miller (Author) "Vaccines: Are They Really Safe and Effective?" (the new, completely updated and revised edition, 2008) is a fully documented guide to immunizations. It includes 30 charts and graphs plus nearly 1,000 citations so that all of the information may be confirmed. This bestselling vaccine handbook (more than 150,000 copies sold) evaluates each vaccine for safety, efficacy, and long-term effects. It contains some of the most comprehensive, up-to-date, uncensored data available -- information that many doctors don't even know. It includes recent studies, numerous case histories detailing vaccine-induced damage to children, and pinpoints for parents exact conditions that may put their own children at high risk. It includes information on vaccine ingredients, natural versus artificial... |
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Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure by Paul A. Offit MD (Author) A London researcher was the first to assert that the combination measles-mumps-rubella vaccine known as MMR caused autism in children. Following this "discovery," a handful of parents declared that a mercury-containing preservative in several vaccines was responsible for the disease. If mercury caused autism, they reasoned, eliminating it from a child's system should treat the disorder. Consequently, a number of untested alternative therapies arose, and, most tragically, in one such treatment, a doctor injected a five-year-old autistic boy with a chemical in an effort to cleanse him of mercury, which stopped his heart instead. Children with autism have been placed on stringent diets, subjected to high-temperature saunas, bathed in magnetic clay, asked to swallow digestive... |
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Shoot 'Em Up: The Truth About Vaccines Starring: David Kirby, Peggy O'Mara, Barbara Loe Fisher, Dan Olmsted, Dr. Stephanie Cave Directed By: Judy Apicella Did you know that America is the only country in the world where vaccinations are mandatory? In 'Shoot 'Em Up' Judy Apicella speaks with the experts as they reveal the damage we unknowingly do to our children. Learn about mercury, formaldehyde and aluminum that some vaccines contain and the autism, asthma and neurological damage they cound contribute to. Could one of the reasons be that most of the individuals who make the decisions about the vaccines kids receive have a financial stake in the drug companies that hold the patents? This reasoned yet brilliant expose is one that the pharmaceutical community hopes you won't see, but is must viewing for all. Easily one of the most important documentaries you will ever see. Also includes 2nd Feature: What Are We Doing To Our... |
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Saying No to Vaccines by Dr. Sherri J. Tenpenny (Author), NMA Media Press (Editor) The most comprehensive guide explaining how and why vaccines are detrimental to your and your childs health. At a time when the vaccine controversey is becoming increasingly hostile, this book offers an in-depth examination of how Saying No to Vaccines can save your and your childs life. Well respected, Dr. Tenpenny is an Internationally recognized expert and the first physician to offer documented proof that vaccines do compromise the immune system. Dr. Tenpenny has the courage and the determination to express a minority view, substantiating her work with citations directly from Centers for Disease Control (CDC) documents and respected, peer-reviewed journals, offering irrefutable facts that fly in the face of information generally regarded as truth in traditional medical circles. |
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