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GEN reports on efforts to quickly develop swine flu vaccine
June 03, 2009Scientists around the world are accelerating their efforts to develop a vaccine against the H1N1 influenza virus (Swine flu) as rapidly as possible, reports Genetic Engineering & Biotechnology News (GEN). The need for such a vaccine received a strong impetus from the World Health Organization, which has issued a Phase 5 pandemic alert, a strong signal that the WHO believes a pandemic is imminent, according to the June 1 issue of GEN (www.genengnews.com/articles/chitem.aspx?aid=2938).
"It can take five or six months to come up with an entirely novel influenza vaccine," says John Sterling, Editor in Chief of GEN. "There is a great deal of hope that biotech and pharma companies might be able to have something ready sooner."
One company, Replikins, actually predicted over a year ago that significant outbreaks of the H1N1 flu virus would occur within 6-12 months. The predictions were based on correlations of flu virus specimens and PubMed documentation of major outbreaks during the past 90 years, focusing on concentrations of, and spacings between, replikins-the lysine and histidine residues in the hemagglutinin (HA) unit genetic sequences of the eight major genes in the influenza virus. Replikins' officials say the company's PanFLu™ vaccine is ready for clinical trials.
Novavax plans to create a virus-like particle-based (VLP) vaccine against the H1N1 strain, which obviates the need for a live virus seed for manufacturing. The VLPs contain the proteins that make the virus' outer shell and the surface proteins, without the RNA required for replication.
Mary Ann Liebert, Inc./Genetic Engineering News
Novavax plans to create a virus-like particle-based (VLP) vaccine against the H1N1 strain, which obviates the need for a live virus seed for manufacturing. The VLPs contain the proteins that make the virus' outer shell and the surface proteins, without the RNA required for replication.
Mary Ann Liebert, Inc./Genetic Engineering News
Vaccine Current Events and Vaccine News RSSMilestone biodefense publication by Elsevier journal Vaccine
Last week during the 'Vaccines for Biothreats and Emerging and Neglected Diseases Symposium' in Galveston TX, USA, the Elsevier journal Vaccine released a supplement dedicated to vaccines for biodefense.
On the Trail of a Vaccine for Lyme Disease: Yale Researchers Target Tick Saliva
A protein found in the saliva of ticks helps protect mice from developing Lyme disease, Yale researchers have discovered. The findings, published in the November 19 issue of Cell Host & Microbe, may spur development of a new vaccine against infection from Lyme disease, which is spread through tick bites.
New findings suggest strategy to help generate HIV-neutralizing antibodies
New discoveries about anti-HIV antibodies may bring researchers a step closer to creating an effective HIV vaccine, according to a new paper co-authored by scientists at the Vaccine Research Center of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
New research helps explain why bird flu has not caused a pandemic
Bird flu viruses would have to make at least two simultaneous genetic mutations before they could be transmitted readily from human to human, according to research published today in PLoS ONE.
Hoping for a fluorescent basket case
Although recent advances have raised hopes that a protective vaccine can be developed, acquired immunodeficiency syndrome (AIDS) remains a major public health problem.
IACC includes vaccine research objective in strategic plan for autism research
Autism Speaks is encouraged by yesterday's decision of the Interagency Autism Coordinating Committee (IACC) to include vaccine research studies in the objectives of the updated Strategic Plan for Autism Research.
'Emotions increase or decrease pain': researchers
Getting a flu shot this fall? Canadians scientists have found that focusing on a pretty image could alleviate the sting of that vaccine.
People with less education could be more susceptible to the flu
People who did not earn a high school diploma could be more likely to get H1N1 and the vaccine might be less effective in them compared to those who earned a diploma, new research shows.
Worksite wellness programs may reduce employee absenteeism
Emory University Rollins School of Public Health researchers will present Nov. 11 on a range of topics at the American Public Health Association's annual meeting in Philadelphia, including a study that found reduced absenteeism among employees participating in a large-scale worksite wellness program.
Scientists explain binding action of 2 key HIV antibodies; could lead to new vaccine design
A very close and detailed study of how the most robust antibodies work to block the HIV virus as it seeks entry into healthy cells has revealed a new direction for researchers hoping to design an effective vaccine.
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Vaccines: Expert Consult (Expert Consult Title: Online + Print) by Stanley A. Plotkin MD (Author), Walter A. Orenstein MD (Author), Paul A. Offit MD (Author) Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety.recommendations for vaccine use, with rationales.data on the impact of vaccination programs on morbidity and mortality.and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing... |
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Saying No to Vaccines by Dr. Sherri J. Tenpenny (Author), NMA Media Press (Editor) The most comprehensive guide explaining how and why vaccines are detrimental to your and your childs health. At a time when the vaccine controversey is becoming increasingly hostile, this book offers an in-depth examination of how Saying No to Vaccines can save your and your childs life. Well respected, Dr. Tenpenny is an Internationally recognized expert and the first physician to offer documented proof that vaccines do compromise the immune system. Dr. Tenpenny has the courage and the determination to express a minority view, substantiating her work with citations directly from Centers for Disease Control (CDC) documents and respected, peer-reviewed journals, offering irrefutable facts that fly in the face of information generally regarded as truth in traditional medical circles. |
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Vaccines: What CDC Documents and Science Reveal Starring: DO Sherri J. Tenpenny |
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Vaccines: Are They Really Safe and Effective by Neil Z. Miller (Author) "Vaccines: Are They Really Safe and Effective?" (the new, completely updated and revised edition, 2008) is a fully documented guide to immunizations. It includes 30 charts and graphs plus nearly 1,000 citations so that all of the information may be confirmed. This bestselling vaccine handbook (more than 150,000 copies sold) evaluates each vaccine for safety, efficacy, and long-term effects. It contains some of the most comprehensive, up-to-date, uncensored data available -- information that many doctors don't even know. It includes recent studies, numerous case histories detailing vaccine-induced damage to children, and pinpoints for parents exact conditions that may put their own children at high risk. It includes information on vaccine ingredients, natural versus artificial... |
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