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Horse whisperers, lion tamers not needed: Scientists find genetic regions that soothe savage beasts
June 09, 2009Research published in the journal Genetics provides the science behind animal temperament
In what could be a breakthrough in animal breeding, a team of scientists from Germany, Russia and Sweden have discovered a set of genetic regions responsible for animal tameness. This discovery, published in the June 2009 issue of the journal GENETICS (http://www.genetics.org), should help animal breeders, farmers, zoologists, and anyone else who handles and raises animals to more fully understand what makes some animals interact with humans better than do others. It may also lead to more precise breeding strategies designed to pass specific genes from one generation to the next as a way to produce tame animals.
"I hope our study will ultimately lead to a detailed understanding of the genetics and biology of tameness," said Frank Albert, a scientist from the Max Planck Institute for Evolutionary Anthropology in Germany and the first author of the research report. "Maybe we'll then be able to domesticate a few of those species where humans have historically not been successful like the wild African Buffalo."
The roots of this study date back to 1972 when researchers in Novosibirsk, USSR (now Russia), caught a large group of rats in the wilderness around the city. After bringing them into the laboratory, the researchers divided them into two groups. The first group included the most "friendly" rats - those that were not aggressive toward people. The second group included only the most aggressive rats - those that screamed, attacked and bit the researchers. Since then, these rats have been bred with one another, and now, the two groups of rats act very differently toward people. The tame rats tolerate being touched and picked up, and never attack. The aggressive rats scream, run away, or attack and bite. For this research study, the scientists mated the tame with the aggressive rats and identified regions in the rat genome that cause a rat to be tamer or more aggressive.
"For thousands of years, humans have domesticated animals," said Mark Johnston, Editor-in-Chief of the journal GENETICS, "and all during this time, much folklore and mythology has surrounded the process. But of course genetics plays a large role in the process, and this research provides a solid scientific explanation of this phenomenon, and offers clues about how genomes can be manipulated to breed tame animals of species once believed to be untamable."
Federation of American Societies for Experimental Biology
The roots of this study date back to 1972 when researchers in Novosibirsk, USSR (now Russia), caught a large group of rats in the wilderness around the city. After bringing them into the laboratory, the researchers divided them into two groups. The first group included the most "friendly" rats - those that were not aggressive toward people. The second group included only the most aggressive rats - those that screamed, attacked and bit the researchers. Since then, these rats have been bred with one another, and now, the two groups of rats act very differently toward people. The tame rats tolerate being touched and picked up, and never attack. The aggressive rats scream, run away, or attack and bite. For this research study, the scientists mated the tame with the aggressive rats and identified regions in the rat genome that cause a rat to be tamer or more aggressive.
"For thousands of years, humans have domesticated animals," said Mark Johnston, Editor-in-Chief of the journal GENETICS, "and all during this time, much folklore and mythology has surrounded the process. But of course genetics plays a large role in the process, and this research provides a solid scientific explanation of this phenomenon, and offers clues about how genomes can be manipulated to breed tame animals of species once believed to be untamable."
Federation of American Societies for Experimental Biology
Genetics Current Events and Genetics News RSSResearchers Identify Role of Gene in Tumor Development, Growth and Progression
Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine researchers have identified a gene that may play a pivotal role in two processes that are essential for tumor development, growth and progression to metastasis.
Genetic analysis helps dissect molecular basis of cardiovascular disease
Using highly precise measurements of plasma lipoprotein concentrations determined by nuclear magnetic resonance spectroscopy (NMR), researchers led by Daniel Chasman at Brigham and Women's Hospital and Harvard Medical School in Boston, MA, the Framingham Heart Study in Framingham, and the PROCARDIS consortium in Stockholm, Sweden and Oxford, England performed genetic association analysis across the whole genome among 17,296 women of European ancestry from the Women's Genome Health Study.
It's a gas: New discovery may lead to heartier, high-yielding plants
In a research report published in the November 2009 issue of the journal GENETICS, scientists show how a family of genes (1-aminocyclopropane-1-carboxylate synthase, or ACS genes) are responsible for production of ethylene.
Gene mismatch influences success of bone marrow transplants
A commonly inherited gene deletion can increase the likelihood of immune complications following bone marrow transplantation, an international team of researchers reports in the November 22 advance online issue of Nature Genetics.
Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene.
Scientists at UA, collaborating institutions decode maize genome
Scientists from the University of Arizona led by Arizona Genomics Institute director Rod A. Wing and from collaborating institutions have deciphered the complete genetic code of the maize plant for the first time.
Ancestry attracts, but love is blind
People preferentially marry those with similar ancestry, but their decisions are not necessarily based on hair, eye or skin colour.
Scientists unlock clues for tailoring corn plant for food, energy needs
Scientists have long known that the offspring of two inbred strains tend to be superior to both their parents. Now, a team of researchers including a University of Florida geneticist has discovered clues to why that might be the case for one of the most important crops in the world: corn.
Causative gene of a rare disorder discovered by sequencing only protein-coding regions of genome
For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder.
New map of variation in maize genetics holds promise for developing new varieties
A new study of maize has identified thousands of diverse genes in genetically inaccessible portions of the genome. New techniques may allow breeders and researchers to use this genetic variation to identify desirable traits and create new varieties that were not easily possible before.
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