Study finds colorectal cancer rates increasing worldwideJune 10, 2009A new study finds colorectal cancer incidence rates for both males and females increased in 27 of 51 countries worldwide between 1983 and 2002, and points to increasing Westernization as being a likely culprit. The rise was seen primarily in economically transitioning countries including Eastern European countries, most parts of Asia, and some countries of South America. The study is the first in a peer-reviewed journal to present colorectal cancer incidence trends across all five continents. It appears in the June 2009 issue of Cancer Epidemiology Biomarkers and Prevention. An accompanying editorial says the rise points toward a failed early detection and prevention strategy as well as failure to address lifestyle and dietary challenges of urbanization that affect most of the globe. Colorectal cancer is the fourth most common cancer in men and the third most common cancer in women worldwide. Previous studies have reported rapid increases in colorectal cancer incidence rates in economically transitioning countries in many parts of the world, likely reflecting changing dietary and physical activity patterns. However, those studies used old data and examined regional or country-specific trends. The new study, led by American Cancer Society epidemiologist Melissa Center, MPH, reviewed colorectal cancer incidence data from 51 cancer registries worldwide with long-term incidence data from the Cancer Incidence in Five Continents (CI5) databases created by the International Agency for Research on Cancer (IARC). Researchers analyzed the change in incidence rates over the past 20 years; 1983-87 through 1998-2002. They found colorectal cancer incidence rates for both males and females increased for 27 of 51 cancer registries considered in the analysis between 1983-87 and 1998-2002. The increases were more prominent for men than for women. Some of the increases were dramatic. For example, in Slovenia, colorectal cancer incidence increased 70 percent among men and 28 percent among women. In Miyagi, Japan, rates rose 92 percent among men and 47 percent among women. The researchers also observed substantial regional and ethnic variations in colorectal cancer incidence trends within countries such as Japan, Israel, and Singapore. The United States was the only country where colorectal cancer incidence rates declined in both males and females. The authors say the increase in colorectal cancer in economically transitioning countries may reflect the adoption of western lifestyles and behaviors. Many of the established and suspected modifiable risk factors for colorectal cancer, including obesity, physical inactivity, smoking, heavy alcohol consumption, a diet high in red or processed meats, and inadequate consumption of fruits and vegetables, are also factors associated with economic development or westernization. The authors say male colorectal cancer incidence rates in the Czech Republic, Slovakia, and Japan have not only exceeded the peak incidence observed in the United States and other long-standing developed nations, but continue to increase. An accompanying editorial by Asad Umar and Peter Greenwald of the Division of Cancer Prevention of the National Cancer Institute calls the rising rates "alarming," saying "this increase points toward a failed early detection and prevention strategy as well as failure to address lifestyle and dietary challenges of urbanization that affect most of the globe." American Cancer Society |
|||||||||||||||||||||
| Related Colorectal Cancer Current Events and Colorectal Cancer News Articles Colon cancer screening more effective earlier in day, UCLA study finds The effectiveness of a screening colonoscopy may depend on the time of day it is performed. According to a new UCLA study, early-morning colonoscopies yielded more polyps per patient than later screenings, and fewer polyps were found hour by hour as the day progressed. 1 disease, not 1 demographic The Asian continent has nearly four billion people living in 47 different countries, and each of these groups has their own unique set of health issues. But when they come to the United States, they're often lumped into one large demographic: "Asian/Pacific Islander." Study shows unsedated colonoscopy for colorectal cancer screening well accepted by patients Researchers from Taiwan report in a new study that unsedated colonoscopy for primary colorectal cancer screening is well accepted in a majority of patients. M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers. The bowels of infection Current research suggests that latent cytomegalovirus (CMV) infection may exacerbate inflammatory bowel disease (IBD). The related report by Onyeagocha et al, "Latent cytomegalovirus infection exacerbates experimental colitis," appears in the November 2009 issue of The American Journal of Pathology. How to Lower Costs, Waiting Times for Colonoscopies Colorectal cancer is a leading cause of cancer-related deaths in the United States, leading to over 50,000 fatalities every year. Excess body weight causes over 124,000 new cancers a year in Europe At least 124,000 new cancers in 2008 in Europe may have been caused by excess body weight, according to estimates from a new modelling study. Adding cetuximab to chemotherapy reduces advanced lung cancer death risk by 13 percent Patients with advanced non-small cell lung cancer who are given cetuximab (Erbitux) in addition to chemotherapy are 13% less likely to die than those who receive chemotherapy alone, regardless of which chemotherapy drug cocktail is used, new research finds. They also experience slower disease progression and an increased chance of tumour shrinkage. New blood tests promise simple, cost-effective diagnosis of gastrointestinal cancers Promising results from two new blood tests that can aid in the early identification of patients with gastrointestinal (GI) cancers will be presented at Europe's largest cancer congress. University of Hawaii at Manoa CRCH scientists report adulthood body size associated with cancer risk A team of scientists led by researcher Brenda Hernandez, Ph.D., M.P.H.-an assistant professor at the University of Hawai'i at Mānoa's Cancer Research Center of Hawai'i-has reported that body mass in younger and older adulthood, and weight gain between these life periods, may influence a man's risk for prostate cancer. More Colorectal Cancer Current Events and Colorectal Cancer News Articles |
|||||||||||||||||||||
|
|||||||||||||||||||||
|
|||||||||||||||||||||