Traumatic brain injury caused by exposure to explosive blast presents critical challengeJune 19, 2009Blast-induced traumatic brain injury (TBI) has reached critical levels in modern-day warfare. The current issue of Journal of Neurotrauma focuses on the intensive efforts to develop effective treatment strategies and model systems for studying the cause and effects of explosive blast TBI. This special issue of Journal of Neurotrauma, a peer-reviewed journal published by Mary Ann Liebert, Inc., is free online at www.liebertpub.com/neu A comprehensive and clearly presented overview of the field entitled "Explosive Blast Neurotrauma" was prepared by a group of authors led by Geoffrey Ling, program officer overseeing the U.S. Defense Advanced Research Projects Agency (DARPA) Preventing Violent Explosive Neurotrauma (PREVENT) blast research program, and colleagues from the Uniformed Services University of the Health Sciences (Bethesda, MD), Duke University Medical Center (Durham, NC), Inova Fairfax Hospital (Virginia), and Integrated Services Group, Inc. (Potomac, MD). Two very instructive examples of current research on blast-induced neurotrauma that describe animal model systems developed to study head injuries sustained during combat are presented in the article entitled, "Blast Overpressure in Rats: Recreating a Battlefield Injury in the Laboratory." Joseph Long and co-authors from Walter Reed Army Institute of Research (Silver Spring, MD), simulated blast effects, evaluated the physiological, neuropathological, and neurobehavioral consequences of airblast exposure, and studied the potential for using a Kevlar vest to prevent death and TBI. The advantages and limitations of using a pig model to study the causes and effects of explosive trauma to the brain is the subject of the article, "An Introductory Characterization of a Combat-Casualty-Care Relevant Swine Model of Closed Head Injury Resulting from Exposure to Explosive Blast," co-authored by a group of researchers from the military, academia, and the private sector, led by Richard Bauman, from Walter Reed Army Institute of Research, Polytrauma & Resuscitation. "We believe the articles in this issue will...provide new insights and stimulate new avenues of investigation into this crucial area of treating our warfighters, as well as the civilian population," write Guest Editors Patrick Kochanek, Richard Bauman, Joseph Long, C. Edward Dixon, and Larry Jenkins, from the University of Pittsburgh School of Medicine and Walter Reed Army Institute of Research, in their Introduction, "A Critical Problem Begging for New Insight and New Therapies." Mary Ann Liebert, Inc./Genetic Engineering News |
|||||||||||||||||||||
| Related Neurotrauma Current Events and Neurotrauma News Articles Researchers Develop 'Lab on a Tube' Monitoring Device The need for improved monitoring of neurotrauma patients has resulted in the development of a prototype of a novel, multitasking "lab on a tube" at the University of Cincinnati (UC). Blood test for brain injuries gains momentum A blood test that can help predict the seriousness of a head injury and detect the status of the blood-brain barrier is a step closer to reality, according to two recently published studies involving University of Rochester Medical Center researchers. Therapeutic hypothermia is promising strategy to minimize tissue damage Recognition of the benefits of cooling strategies to protect the brain and spinal cord after traumatic injury has led to a wealth of cutting edge research, prime examples of which are featured in a special hypothermia issue of Journal of Neurotrauma. Severe retinal hemorrhaging is linked to severe motor vehicle crashes The severity of retinal hemorrhaging for young children in motor vehicle crashes is closely correlated to the severity of the crash, according to a new study by researchers at the Medical College of Wisconsin in Milwaukee. Leading experts investigate Shaken Baby Syndrome Shaken Baby Syndrome (SBS), also known as childhood neurotrauma or inflicted traumatic brain injury, is the leading cause of death from childhood maltreatment. Researchers identify key protein involved in neuropathic pain A team of researchers led by Université Laval and The Hospital for Sick Children (SickKids) has discovered a protein that plays a major role in neuropathic pain. New technique puts brain-imaging research on its head It's a scene football fans will see over and over during the bowl and NFL playoff seasons: a player, often the quarterback, being slammed to the ground and hitting the back of his head on the landing. More Neurotrauma Current Events and Neurotrauma News Articles |
|||||||||||||||||||||
|
|||||||||||||||||||||
|
|||||||||||||||||||||