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Exposure to phthalates may be a risk factor for low birth weight in infants
June 25, 2009Many parents worry about their child's exposure to phthalates, the chemical compounds used as plasticizers in a wide variety of personal care products, children's toys, and medical devices. Phthalate exposure can begin in the womb and has been associated with negative changes in endocrine function. A new study soon to be published in the Journal of Pediatrics examines the possibility that in utero phthalate exposure contributes to low birth weight in infants. Low birth weight is the leading cause of death in children under 5 years of age and increases the risk of cardiovascular and metabolic disease in adulthood.
To investigate the associations between in utero phthalate exposure and low birth weight, Dr. Renshan Ge of the Population Council and colleagues from Fudan University and Second Military Medical University in Shanghai studied 201 pairs of newborns and their mothers between 2005 and 2006. Of the 201 infants studied, 88 were born with low birth weight. The researchers analyzed samples of the infants' meconium, the first bowel movement that occurs after birth, and cord blood to determine phthalate levels.
They found quantifiable levels of phthalate and phthalate metabolites in more than 70% of the samples. Infants with low birth weight had consistently higher levels of phthalates. According to Dr. Ge, "The results showed that phthalate exposure was ubiquitous in these newborns, and that prenatal phthalate exposure might be an environmental risk factor for low birth weight in infants." Although these associations are not conclusive, this study supports the accelerating efforts to minimize phthalate exposure.
Elsevier Health Sciences
Elsevier Health Sciences
Common plastics chemicals linked to ADHD symptoms
Phthalates are important components of many consumer products, including toys, cleaning materials, plastics, and personal care items.
Pilot study relates phthalate exposure to less-masculine play by boys
A study of 145 preschool children reports, for the first time, that when the concentrations of two common phthalates in mothers' prenatal urine are elevated their sons are less likely to play with male-typical toys and games, such as trucks and play fighting.
Health Risks of Phthalates
Phthalates, largely used as plasticisers, have long been suspected in connection with rising infertility rates, particularly among men. These substances are quite common and are considered highly hazardous to human health because they disrupt the hormonal balance and impair reproduction and development. What has not been clear up to now is the amount of phthalates that enter the human body. The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is funding a research project at the University of Erlangen-Nürnberg under the leadership of Professor Jürgen Angerer that is studying the environmental uptake of phthalates in the population. The results thus far have shown t
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