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Common antibacterial treatment linked to sensorineural hearing loss in cystic fibrosis patients
July 01, 2009Alexandria, VA - An otherwise effective treatment for cystic fibrosis places patients at a high risk of sensorineural hearing loss, according to new research published in the July edition of Otolaryngology-Head and Neck Surgery.
Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide). A defective gene and its protein product cause the body to produce unusually thick, sticky mucus that clogs the lungs and leads to life-threatening lung infections; and obstructs the pancreas and stops natural enzymes from helping the body break down and absorb food.
Researchers reviewed the medical records of cystic fibrosis (CF) patients at Children's Hospital Boston over a 13 year period, and found that seven of 50 CF patients (14%) suffered from sensorineural hearing loss. Of that group, 43 percent of those that had received aminoglycosides intravenously had received more than 10 courses of the treatment; patients who were treated more than five times with nasal irrigation of aminoglycosides were also at risk of sensorineural hearing loss.
Because CF patients are prone to suffer from infections of the pulmonary and sinonasal systems, aminoglycosides are commonly administered to CF patients because of the potent effect they have on bacteria. The treatment is considered so effective that it outweighs the well-known side-effects, which include hair cell loss, and thus hearing loss.
The authors contend that CF patients should have routine hearing evaluations that specifically target the detection of sensorineural hearing loss, especially when repeated courses of systemic or intranasal aminoglycosides have be used in treatment. They also note that further investigation through a prospective study is warranted in order to replicate these results.
American Academy of Otolaryngology -- Head and Neck Surgery
Because CF patients are prone to suffer from infections of the pulmonary and sinonasal systems, aminoglycosides are commonly administered to CF patients because of the potent effect they have on bacteria. The treatment is considered so effective that it outweighs the well-known side-effects, which include hair cell loss, and thus hearing loss.
The authors contend that CF patients should have routine hearing evaluations that specifically target the detection of sensorineural hearing loss, especially when repeated courses of systemic or intranasal aminoglycosides have be used in treatment. They also note that further investigation through a prospective study is warranted in order to replicate these results.
American Academy of Otolaryngology -- Head and Neck Surgery
Many children with hearing loss also have eye disorders
About one-fifth of children with sensorineural hearing loss also have ocular disorders, according to a report in the February issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.
Can you hear me now? Stem cells enhance hearing recovery
Researchers have shown that bone marrow stem cells injected into a damaged inner ear can speed hearing recovery after partial hearing loss.
Evidence lacking to guide treatment for sudden hearing loss
Although steroids are the most widely used treatment for sudden hearing loss, little scientific evidence supports their use or that of any other therapies for this condition.
Risk factors identified for hearing loss in children with bacterial meningitis
Researchers have identified several risk factors that are associated with the development of hearing loss in children with bacterial meningitis.
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Tinnitus Care by Bio Essence Tinnitus Care is an herbal formula used widely in the ENT department of the First People Hospital of Hangzhou. This hospital is well known in China for. The ENT department for more than 20 years has used Tinnitus Care. Tinnitus Care is for people who are diagnosed with Sensorineural Hearing Loss (SHL). It is almost 99% effective rate used in the First People Hospital in Hang Zhou, China for symptom relief or decrease. Patients only need to take it for two weeks as a course of treatment. The TCM diagnosis for SHL is a kidney deficiency. It is not for the immune system problems, like rheumatoid arthritis which can cause hearing loss or ear ringing caused by Liver Fire. |
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