Science Current Events | Science News | Brightsurf.com
 

Is molecular adsorbent recirculating system effective for all the liver failure patients?

July 08, 2009
Since its introduction in 1993, molecular adsorbent recirculating system (MARS) albumin dialysis has been a subject of research, with the hope of treating effectively patients with acute liver failure. The impact of MARS treatment on outcome as well as clinical and laboratory variables has been investigated widely in small non-randomized studies. However, larger studies with longer follow-up time are required to determine the true usefulness of MARS treatment in different liver failure etiologies.

An article to be published on June 28 2009 in the World Journal of Gastroenterology addressed this issue. The research led by Taru Kantola from Helsinki University Central Hospital, Finland discussed the prognostic factors for survival in patients with acute liver failure. The authors analysed the 1-year outcomes of 188 patients treated with MARS from 2001 to 2007, in an intensive care unit specializing in liver diseases.

They found that the etiology of liver failure was the most important predictor of survival. In acute liver failure (ALF) of toxic etiology (e.g., paracetamol), the grade of encephalopathy before MARS treatment was a significant prognostic factor. In ALF of unknown etiology, coagulation factor 5 and liver enzyme alanine aminotransferase levels were prognostic. According to the results, the MARS treatment of a cirrhotic patient with an acute-on-chronic liver failure is not meaningful in terms of prognosis if the patient is not eligible for transplantation.

World Journal of Gastroenterology


Related Liver Failure Current Events and Liver Failure News Articles


UI researchers find early predictor for preeclampsia
University of Iowa researchers have discovered a biomarker that could give expecting mothers and their doctors the first simple blood test to reliably predict that a pregnant woman may develop preeclampsia, at least as early as 6 weeks into the pregnancy.

Fat damages the lungs of heavy drinkers
Heavy drinking damages the body in many ways. In addition to liver failure, alcoholics are at a much greater risk of developing pneumonia and life threatening acute respiratory distress syndrome (ARDS), for which there is no treatment.

Combination therapy a potential strategy for treating Niemann Pick disease
By studying nerve and liver cells grown from patient-derived induced pluripotent stem cells (iPSCs), Whitehead Institute researchers have identified a potential dual-pronged approach to treating Niemann-Pick type C (NPC) disease, a rare but devastating genetic disorder.

Steroids after surgery do not help infants with rare liver disease
Infants who received corticosteroids following bile duct surgery to treat a rare liver disease known as biliary atresia experienced no clinical benefit of the medicine and could suffer harm.

New combination drug therapy proves very effective in hepatitis C treatments
Treatment options for the 170 million people worldwide with chronic Hepatitis C Virus (HCV) are evolving rapidly, although the available regimens often come with significant side effects.

Obeticholic acid produces meaningful biochemical and clinical improvements in PBC cirrhosis patients
Results from an international Phase III study presented today at the International Liver CongressTM 2014 have shown obeticholic acid (OCA) given to patients suffering from Primary Biliary Cirrhosis (PBC) who previously had an inadequate response to, or have been unable to tolerate ursodeoxycholic acid (UDCA), produced meaningful biochemical and clinical improvements.

New prediction model to improve patient survival after paracetamol-related liver failure
In the UK paracetamol toxicity is the most common cause of ALF and has a high mortality rate. It is estimated that 150 to 200 deaths and 15 to 20 LTs occur as a result of poisoning each year in England and Wales.

Erasing a genetic mutation
Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation.

Standardized evaluation consent forms for living liver donors needed
New research reveals that 57% of liver transplant centers use living donor evaluation consent forms that include all the elements required by the Centers for Medicare and Medicaid Services (CMS) and 78% of centers addressed two-third or more of the items recommended by the Organ Procurement and Transplant Network (OPTN).

Liver transplant may arrest neurological damage in a rare and progressive form of autism
A patient with a rare metabolic disease that causes liver failure and autistic behavior experienced significant improvements in both her physical and mental health after receiving a liver transplant, according to a new case report published in the American Journal of Transplantation.
More Liver Failure Current Events and Liver Failure News Articles

Liver Failure

Liver Failure


Liver Failure

Heal Your Liver - Detoxify and repair your liver with the most potent supplements available today

Heal Your Liver - Detoxify and repair your liver with the most potent supplements available today


Want to restore liver function, cleanse and detoxify your liver and reverse liver disease using the four most potent liver supplements available today?Which substance is given to emergency room patients to prevent liver failure from Tylenol/Panadol overdose? This life-saving substance is also available in simple tablet form.Along with the brain and the heart, the liver has a strong case to claim its position as one of your most vital organs. It is involved in such as wide range of processes going on inside your body that when things go wrong with your liver, the consequences can be fatal.However, despite its importance, we continue to bombard the liver with poor diet and lifestyle, along with the over-consumption of alcohol and drugs (both legal and illegal). Your liver is your front line...

The Gift: Our Journey Through Liver Failure And Liver Transplant

The Gift: Our Journey Through Liver Failure And Liver Transplant
by Pam Dyer (Author), Lou Belcher (Editor)


Our life and death struggle with liver cirrhosis, also known as Nonalcoholic Steatohepatitis or NASH. Life seemed to hover just out of his reach and death always seemed to be looming. We hoped he would live long enough to get added to the organ transplant list. A donor liver would be lifesaving. He wouldn't survive long without one. It made us sad knowing he could only live if someone else died. It seemed to take forever to get a referral to a transplant hospital, largely because he was gravely ill. Even so, would he live long enough to get on the organ transplant list and receive a transplant? Time was not our friend.

Liver Failure, An Issue of Critical Care Nursing Clinics, 1e (The Clinics: Nursing)

Liver Failure, An Issue of Critical Care Nursing Clinics, 1e (The Clinics: Nursing)
by Sarah Saxer PharmD (Author), Dinesh Yogaratnam PharmD BCPS (Author), Tenita Foston NP (Author)


This issue of Critical Care Nursing Clinics, guest edited by Sarah Saxer, PharmD, Dinesh Yogaratnam, PharmD, BCPS, and Tenita Foston, NP, on the topic of Liver Failure, will include the following article subjects: Drug-Induced Liver Failure: A Focus on Acetaminophen Overdose; Current and Emerging Strategies for Treating Hepatic Encephalopathy; Drug Dosing Considerations for the Critically Ill Patient with Liver Disease; Critical Care Therapies for Bleeding Esophogeal Varices; Treating Coagulopathies in Fulminant Hepatic Failure; Treating HCV; Management HBV; Hepatorenal Syndrome; Hepatopulmonary Syndrome; Live Transplant Considerations for Evaluation; Hepatocellular Carcinoma; Cholestatic Live Disease; Nutrition in ESLD; Infectious Issues in Patients with Liver Disease; and Management...

The Liver and Gallbladder Miracle Cleanse: An All-Natural, At-Home Flush to Purify and Rejuvenate Your Body

The Liver and Gallbladder Miracle Cleanse: An All-Natural, At-Home Flush to Purify and Rejuvenate Your Body
by Andreas Moritz (Author)


TAKE CHARGE OF YOUR HEALTH WITH THE LIVER AND GALLBLADDER MIRACLE CLEANSE

Most people unknowingly suffer from a dangerous buildup of gallstones in the liver and gallbladder. These stones clog up the body’s cleansing organs, creating a toxic environment incapable of maintaining good health. You become fatigued, your tissues inflame, you gain weight, and your immune system stops fighting off illness
and disease.

Now, The Liver and Gallbladder Miracle Cleanse teaches you how to easily and painlessly remove gallstones in the comfort of your own home. Ridding your body of these disease-causing stones allows you to reclaim your health and vitality while relieving your suffering from symptoms of toxic gallstone buildup,...

Acute Liver Failure

Acute Liver Failure
by William M. Lee (Editor), Roger Williams (Editor), Jean-Pierre Benhamou (Editor), Jacques Bernuau (Editor)


Acute liver failure (ALF), or fulminant hepatic failure, is a distinct clinical syndrome that crosses medical disciplines. A relatively rare condition, ALF remains a major focus of clinical and research attention. With the advent of transplantation, the importance of understanding management of ALF has taken on a new urgency. In this first volume dedicated to ALF, the editors bring together a distinguished team of contributors to describe the etiology, pathology and treatment of this important syndrome. Also covered are consensus techniques in liver transplantation for ALF patients, as well as descriptions of artificial and bioartificial liver assist devices. A section on future treatments includes hepatocyte transplantation, auxiliary grafts and other temporary liver support....

Chronic Liver Failure: Mechanisms and Management (Clinical Gastroenterology)

Chronic Liver Failure: Mechanisms and Management (Clinical Gastroenterology)
by Pere Ginès (Editor), Patrick S Kamath (Editor), Vicente Arroyo (Editor)


Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but...

Liverwurst: Work Made at the onset of end-stage liver failure until live-donor organ transplantation (December 2007-June 2009)

Liverwurst: Work Made at the onset of end-stage liver failure until live-donor organ transplantation (December 2007-June 2009)
by Ella F.B. Watson (Author)


"The process of transplantation is a grueling one- demanding physical participation in a battery of tests and procedures as well as an emotional commitment to oneself and acceptance of the unknown. This is a beautiful catalogue of stories, photographs and drawings that tell Ella's story of chronic illness and her journey towards transplant. Throughout this process she demonstrates a remarkable spirit and strength despite loss, illness and ever present chance of dying. Through her art and words she provides a window into her soul as she faces her own mortality with grace, maturity and humor." ---Ariana Rose, Nurse Practitioner 

 "The remarkable hospital sketchbook of artist Ella Watson chronicles her two year crisis battling end-stage liver failure. A young...

Obese Children and the Complications They Face, Diabetes, Heart, Liver and Kidney Failure, Blindness, Amputation and Nerve Damage

Obese Children and the Complications They Face, Diabetes, Heart, Liver and Kidney Failure, Blindness, Amputation and Nerve Damage


Childhood Obesity has become a global problem. Obese Kids aged 10 years are developing, among other diseases, Type 2 Diabetes, also known as Adult Onset Diabetes, in other words, an "Old Person's Disease".
They haven't even found a name for it yet, and many of the medications being used are not suited for kid's use.
This book has been written by a type 2 diabetic who, some 20 years after contracting the disease, has developed at least two of the main complications, severe nerve damage and a muscle wasting disease. But there are many complications with far worse effects than these.
The shock at finding that ten year olds were getting type 2 diabetes because
of obesity has compelled him to write this book in an attempt to wake people up to these complications.

The Amazing Liver & Gallbladder Flush

The Amazing Liver & Gallbladder Flush
by Andreas Moritz (Author)


In this revised edition of his best-selling book, formerly The Amazing Liver Cleanse, Andreas Moritz addresses the most common but rarely recognized cause of illness - gallstones congesting the liver. Twenty million Americans suffer from attacks of gallstones every year. In many cases, treatment merely consists of removing the gallbladder, at the cost of $5 billion a year. But this purely symptom-oriented approach does not eliminate the cause of the illness, and in many cases, sets the stage for even more serious conditions. Most adults living in the industrialized world, and especially those suffering a chronic illness such as heart disease, arthritis, MS, cancer, or diabetes, have hundreds if not thousands of gallstones (mainly clumps of hardened bile) blocking the bile ducts of their...

© 2014 BrightSurf.com