Nepean Dyspepsia Index applies to functional dyspepsia in ChinaJuly 16, 2009FD, a common non-organic disease in the world, greatly affects the patient's quality of life. However, treatment of FD is still controversial and no single therapy is uniformly effective, due, in part, to absence of a reliable evaluation instrument. The Nepean Dyspepsia Index (NDI), measuring both symptom scores and impairment of the dyspepsia-specific health-related quality of life in FD patients, has been designed to diagnose FD and translated into several languages. Moreover, its utility has been proved to be validated by researches in western countries. However, DI has not been translated and validated in China./p> A research article to be published on July 7, 2009 in the World Journal of Gastroenterology addresses this question. The research team led by Professor Liang from Chengdu University of Traditional Chinese Medicine translated NDI and assessed the reliability and validity of this translated version in Chinese patients. /p> According to the WHO-QOL methodology of cross-culture adaptation for quality of life, the NDI was formally translated from the original version into Chinese, including forward translation, back translation, a pretest and cross-cultural adaptation. In additional, internal consistency analysis with Cronbath's alpha was performed to its reliability. Pearson Item-Dimension Correlation coefficient was employed to evaluate content validity. Factor analysis and structural equation models were used to assess construct validity./p> The study indicated that the Chinese version of the NDI is a reliable and valid scale for measuring health-related quality of life (H-QOL) and disease severity in Chinese patients with functional dyspepsia. It is recommended to be used in FD-related clinical researches in China in the future. World Journal of Gastroenterology |
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| Related Dyspepsia Current Events and Dyspepsia News Articles Antidepressant and placebo are equally effective in child pain relief When used "off-label," the antidepressant amitriptyline works just as well as placebo in treating pain-predominant gastrointestinal disorders in children, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. Care-seeking behavior associated with 'upper-GI symptoms' Patients with upper gastrointestinal (GI) complaints visit their general practitioner (GP) more often than patients with other conditions. Acid-reducing medicines may lead to dependency Treatment with proton pump inhibitors (PPIs) for eight weeks induces acid-related symptoms like heartburn, acid regurgitation and dyspepsia once treatment is withdrawn in healthy individuals. NPs-NPR-B/pGC-cGMP signal pathway is involved in diabetic gastroparesis The natriuretic peptide (NP) receptor type B (NPR-B) gene was expressed in gastric smooth muscles of normal and diabetic rats and the expression was increased in diabetic rats. Acute gastric injury due to high-dose analgesics? Analgesics, NSAIDs and acetaminophen, are commonly used for the relief of fever, headaches, and other minor aches and pains. The gastrointestinal side effects of NSAIDs are well documented and acetaminophen is accepted to be a safe drug for the gastrointestinal system. Acute effects of short-term, especially high-dose NSAID and acetaminophen use have not been studied adequately. Nearly 40 percent of GERD patients taking PPIs experience recurring symptoms Despite daily use of doctor-recommended proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) symptoms, nearly 40 percent of patients who take them continue to experience breakthrough, which is a return of GERD symptoms, such as acid regurgitation and heartburn. A strange case of upper obstructive syndrome Aorto-duodenal fistulae (ADF) are the most frequent aorto-enteric fistulae (80%) and the most frequent presenting sign of ADF is upper gastrointestinal bleeding (UGI). ASGE offers guidelines on endoscopic treatment of dyspepsia The American Society for Gastrointestinal Endoscopy (ASGE) has issued guidelines for the role of endoscopy in treating dyspepsia, discomfort thought to arise from the upper-gastrointestinal tract, which affects a fourth of the population in Western countries. Study measures impact on productivity from functional gastrointestinal disorders Those who suffer from common functional gastrointestinal disorders face work productivity losses and impairments in daily activity that amount to the loss of at least one day of work in a 40-hour workweek. Common abdominal pain may be due to a potentially treatable newly recognized inflammatory reaction As many as one in four people in westernized countries experience pain or discomfort in their upper abdomen, and physicians have almost nothing to offer except anti-acid medicines, which usually don't work. More Dyspepsia Current Events and Dyspepsia News Articles |
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