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An inner 'fingerprint' for personalizing medical care
July 23, 2009Fingerprints move over. Scientists are reporting evidence that people have another defining trait that may distinguish each of the 6.7 billion humans on Earth from one another almost as surely as the arches, loops, and whorls on their fingertips. In a study scheduled for the Aug. 7 issue of ACS' monthly publication the Journal of Proteome Research, they report evidence from studies in humans for the existence of unique patterns in metabolism.
Metabolism is a whole caboodle of chemical processes. The body uses to turn food into energy, grow, repair damage from diseases and injuries, use medicines, and carry out other functions necessary to continue living. In the new study, Ivano Bertini and colleagues cite growing evidence that each individual has a unique metabolic profile. It's a biochemical counterpart to fingerprints that can be detected by analyzing the chemical whorls and grooves that result from metabolism and can be detected in the urine.
Doctors have dreamed of using such tests for the early diagnosis of disease and personalized medical care. They could pick drugs and treatments that are best for each individual, rather than today's one-size-fits all medicine. To do so, however, doctors need evidence that the metabolic fingerprint remains stable over a period of years, with changes due to disease or medications, for instance, but not advancing age or other factors. The new study provides that evidence, based on the analysis of over 1,800 urine samples from people monitored for 2-3 years. Researchers could identify individual patients from their metabolic profiles with an accuracy of over 99 percent. The study could pave the way for using metabolic profiling to apply personalized medical care, the researchers suggest.
American Chemical Society
American Chemical Society
Metabolism Current Events and Metabolism News RSSWomen Can Quit Smoking and Control Weight Gain
Many women don't quit smoking because they are afraid of gaining weight. That's because nicotine suppresses the appetite and boosts a smoker's metabolism.
Scripps research scientists find new link between insulin and core body temperature
A team led by scientists at The Scripps Research Institute have discovered a direct link between insulin-a hormone long associated with metabolism and metabolic disorders such as diabetes-and core body temperature.
Researchers begin to decipher metabolism of sexual assault drug
It's a naturally occurring brain chemical with an unwieldy name: 4-hydroxybutyrate (4-HB). Taken by mouth, it can be abused or used as a date-rape drug.
Cancers' Sweet Tooth May Be Weakness
The pedal-to-the-metal signals driving the growth of several types of cancer cells lead to a common switch governing the use of glucose, researchers at Winship Cancer Institute of Emory University have discovered.
Scientists find molecular trigger that helps prevent aging and disease
Researchers at Mount Sinai School of Medicine set out to address a question that has been challenging scientists for years: How do dietary restriction-and the reverse, overconsumption-produce protective effects against aging and disease?
Night Beat, Overtime and a Disrupted Sleep Pattern Can Harm Officers' Health
A police officer who works the night shift, typically from 8 p.m. to 4 a.m., already is at a disadvantage when it comes to getting a good "night's" sleep.
MIT scientists pinpoint origin of dissolved arsenic in Bangladesh drinking water
Researchers in MIT's Department of Civil and Environmental Engineering believe they have pinpointed a pathway by which arsenic may be contaminating the drinking water in Bangladesh, a phenomenon that has puzzled scientists, world health agencies and the Bangladeshi government for nearly 30 years.
New paper describes connections between Circadian and metabolic systems
A paper by University of Notre Dame biologist Giles Duffield and a team of researchers offers new insights into a gene that plays a key role in modulating the body's Circadian system and may also simultaneously modulate its metabolic system.
New evidence that dark chocolate helps ease emotional stress
The "chocolate cure" for emotional stress is getting new support from a clinical trial published online in ACS' Journal of Proteome Research.
'Escaped' proteins add to hearing loss in elderly, UF researchers find
Age-related hearing loss is the most common sensory disorder among the elderly. But scientists are still trying to figure out what cellular processes govern or contribute to the loss.
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Master Your Metabolism: The 3 Diet Secrets to Naturally Balancing Your Hormones for a Hot and Healthy Body! by Jillian Michaels (Author), Mariska van Aalst (Author) Does it feel as if you re fighting your body to lose even one pound or just to maintain your current weight? Respected health and wellness expert and bestselling author Jillian Michaels has been there, too. So she consulted top experts in the field of metabolism and discovered that she d inadvertently been abusing her endocrine system for years. After fixing her own metabolism, she decided to share what she learned by devising this simple, 3-phase plan that engages all the weight-loss hormones (including the friendly HGH, testosterone, DHEA; and the not-so-friendly: insulin, cortisol, and excess estrogen). In Master Your Metabolism, discover how to: REMOVE anti-nutrients from your diet RESTORE foods that speak directly to fat-burning genes REBALANCE energy and your... |
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Source Naturals L-Tryptophan, 500 mg, Capsules, 120 capsules by Source Naturals Dietary supplement. Mood, relaxation, sleep. The essential amino acid L-Tryptophan helps support relaxation, restful sleep, and feeling better. It plays a part in the synthesis of both melatonin and serotonin, hormones involved with mood and stress response. L-Tryptophan also supports immune functions because it is the body's precursor to the kynurenines that regulate immunity. If needed, L-Tryptophan converts to niacin in the body, which supports circulation, a healthy nervous system, the metabolism of food, and the production of hydrochloric acid for the digestive system. Source Naturals L-Tryptophan is extremely pure and is regularly tested to ensure the highest standards of quality. (These statements have not been evaluated by the Food and Drug Administration. This product is not... |
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