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Is it possible to differentiate GISTs from leiomyomas by endoscopic ultrasonography?
July 29, 2009A research article to be published on July 21, 2009 in the World Journal of Gastroenterology addresses this question. This research led by Professor Kim and his colleagues in Pusan National University, South Korea. They evaluated the EUS features of gastric GISTs in comparison with gastric leiomyomas, and tried to determine the EUS features that could predict the malignant potential of gastric GISTs according to the histological risk classification.
In their study, to differentiate GISTs from leiomyomas by EUS, the following four features were helpful; inhomogenicity, hyperechogenic spots, a marginal halo and higher echogenicity as compared with the surrounding muscle layer. These features appeared more frequently in GISTs than in leiomyomas. The presence of at least two of these four features had a sensitivity of 89.1% and a specificity of 85.7% for predicting GISTs. Except for tumor size and irregularity of the border, most of the EUS features were not helpful in predicting the malignant potential of GISTs. On multivariate analysis, only the maximal diameter of the GISTs was an independent predictor. The optimal size for predicting malignant GISTs was 35 mm. The sensitivity and specificity using this value were 92.3% and 78.8%, respectively.
Gastric mesenchymal tumors are often asymptomatic, and they are usually incidentally discovered during upper gastrointestinal endoscopy for unrelated conditions. The main problem in the asymptomatic patient is to determine whether or not the tumors have a malignant potential. Because GISTs have malignant potential, gastric mesenchymal tumors, even if they are small, should not be ignored if the EUS features are suggestive of GISTs. Even though, there are already a large number of publications on the EUS-features of stromal cell tumors available, this research would provide an additional clinical approach guideline in patients with gastric mesenchymal tumors.
World Journal of Gastroenterology
World Journal of Gastroenterology
New MR Sequence Helps Radiologists More Accurately Evaluate Abnormalities of the Uterus and Ovaries
A new MR imaging sequence, T2-weighted BLADE, used to image the female pelvis improves image quality and helps radiologists make a more accurate diagnosis, according to a study performed at the University of Maryland School of Medicine in Baltimore, MD.
Major surgery no longer needed for the removal of uterine fibroids
The treatment of uterine fibroids with 3T MR-guided focused ultrasound (MRgFUS) is safe, non-invasive and effective, according to a recent study conducted by researchers at Weill Cornell Medical College in New York, NY.
Endoscopic resection is a safe and effective treatment for gastrointestinal smooth muscle tumors
Gastrointestinal smooth muscle tumors (SMTs, including leiomyoma and leiomyosarcoma) represent relatively common lesions that are thought to originate from a muscular layer of the gastrointestinal tract.
Harmful chemicals may reprogram gene response to estrogen
New research shows that exposure to harmful chemicals and drugs during critical developmental periods early in life may actually "reprogram" the way certain genes respond to the female hormone estrogen. This genetic reprogramming may determine whether people with a genetic predisposition for a disease actually develop the disease.
World first for Swedish researchers - mice born from transplanted wombs
Swedish scientists and doctors have transplanted uteri from one set of mice to another and produced normal healthy babies from the transplanted wombs. This is the first time that live births have been achieved from transplanted uteri in any species. It proves that transplanted uteri can harbour pregnancies and provides hope that successful womb transplants will be possible in women in the future. The team from Sahlgrenska University, Göteborg, are presenting their work this week to the annual meeting of the European Society of Human Reproduction and Embryology in Madrid. Team leader Professor Mats Br'¤nnström told a news briefing today (Tuesday 1 July) that they have developed a technique
More Leiomyomas Current Events and Leiomyomas News Articles
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Uterine Leiomyomas: Pathogenesis and Management by Ivo Brosens (Author) This is an advanced clinical reference on the pathogenesis, clinical presentation, and treatment of uterine fibroids. The pathogenesis section focuses on the current understanding of the biological basis of fibroid development. The chapters on clinical aspects cover epidemiology, assessment and clinicopathological features. The main focus of the book is on the contemporary management of fibroids, which has undergone a revolution during the past decade with a better understanding of the impact on fertility and technical advances in endoscopic surgery, radiologic embolization and pharmaceutical alternatives such as GnRH-superagonists and progesterone intrauterine devices. |
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Massive multilocular cystic leiomyoma of the uterus: an extreme example of hydropic degeneration.: An article from: Southern Medical Journal by Kathleen Coard (Author), Joseph Plummer (Author) This digital document is an article from Southern Medical Journal, published by Thomson Gale on March 1, 2007. The length of the article is 2208 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Massive multilocular cystic leiomyoma of the uterus: an extreme example of hydropic degeneration. Author: Kathleen Coard Publication: Southern Medical Journal (Magazine/Journal) Date: March 1, 2007 Publisher: Thomson Gale Volume: 100 Issue: 3 Page: 309(4) Distributed by Thomson... | |
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Sinonasal leiomyoma: report of 2 cases.: An article from: Ear, Nose and Throat Journal by A.K. Agarwal (Author), Ramanuj Bansal (Author), Deepti Singhal (Author) This digital document is an article from Ear, Nose and Throat Journal, published by Thomson Gale on April 1, 2005. The length of the article is 2213 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Sinonasal leiomyoma: report of 2 cases. Author: A.K. Agarwal Publication: Ear, Nose and Throat Journal (Magazine/Journal) Date: April 1, 2005 Publisher: Thomson Gale Volume: 84 Issue: 4 Page: 224(6) Distributed by Thomson... | |
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Cutaneous leiomyomas: a clinical marker of risk for hereditary leiomyomatosis and renal cell cancer.(ce series): An article from: Dermatology Nursing by Laveta Stewart (Author), Gladys Glenn (Author), Jorge R. Toro (Author) This digital document is an article from Dermatology Nursing, published by Thomson Gale on August 1, 2006. The length of the article is 3414 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. From the author: Cutaneous leiomyomas are a prominent marker of hereditary leiomyomatosis and renal cell cancer (HLRCC). Their appearance, symptoms, and pathology aid in recognition of HLRCC. Presence raises caution, due to potentially associated uterine leiomyomas and aggressive renal cell cancer. Screening for HLRCC is recommended for individuals with multiple cutaneous leiomyomas. Citation Details Title:... | |
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Pulmonary lymphangioleiomyomatosis in combination with uterine leiomyoma in a postmenopausal woman.(Letter to the editor): An article from: Southern Medical Journal by Nurdan Kokturk (Author), Senay Demirtas (Author), Hatice Bakir (Author), Haluk Turktas (Author), Nalan Akyurek (Author), Cemil D. Yorgancilar (Author), Sedat Demircan (Author), Nilgun Kapucuoglu (Author) This digital document is an article from Southern Medical Journal, published by Thomson Gale on November 1, 2006. The length of the article is 723 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Pulmonary lymphangioleiomyomatosis in combination with uterine leiomyoma in a postmenopausal woman.(Letter to the editor) Author: Nurdan Kokturk Publication: Southern Medical Journal (Magazine/Journal) Date: November 1, 2006 Publisher: Thomson Gale Volume: 99 Issue: 11 Page: 1312(2) Article Type: Letter to the editor Distributed by Thomson... | |
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Skin leiomyomas may portend severe syndrome; skin lesions tend to predate other manifestations of the disease by 5-10 years, boosting their relevance.(Clinical ... An article from: Skin & Allergy News by Betsy Bates (Author) This digital document is an article from Skin & Allergy News, published by International Medical News Group on June 1, 2005. The length of the article is 449 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Skin leiomyomas may portend severe syndrome; skin lesions tend to predate other manifestations of the disease by 5-10 years, boosting their relevance.(Clinical Rounds) Author: Betsy Bates Publication: Skin & Allergy News (Magazine/Journal) Date: June 1, 2005 Publisher: International Medical News Group Volume: 36 Issue: 6 Page: 32(1) Distributed by... | |
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Multiple skin leiomyomas may portend symptomatic fibroids.(Gynecology): An article from: OB GYN News by Betsy Bates (Author) This digital document is an article from OB GYN News, published by International Medical News Group on May 15, 2005. The length of the article is 455 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Multiple skin leiomyomas may portend symptomatic fibroids.(Gynecology) Author: Betsy Bates Publication: OB GYN News (Magazine/Journal) Date: May 15, 2005 Publisher: International Medical News Group Volume: 40 Issue: 10 Page: 11(1) Distributed by Thomson... | |
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Leiomyoma - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by ICON Health Publications (Author) In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. |
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Malignant gastric stromal tumor: unusual metastatic patterns. (Case Report).(medical research): An article from: Southern Medical Journal by Obinna C. Igwilo (Author), Mitchel P. Byrne (Author), Khoa D. Nguyen (Author), Janis Atkinson (Author) This digital document is an article from Southern Medical Journal, published by Southern Medical Association on May 1, 2003. The length of the article is 2019 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Malignant gastric stromal tumor: unusual metastatic patterns. (Case Report).(medical research) Author: Obinna C. Igwilo Publication: Southern Medical Journal (Refereed) Date: May 1, 2003 Publisher: Southern Medical Association Volume: 96 Issue: 5 Page: 512(4) Distributed by Thomson... | |
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Fibroids; Prevention.: An article from: NWHRC Health Center - Fibroids by Thomson Gale (Publisher) This digital document is an article from NWHRC Health Center - Fibroids, published by Thomson Gale on March 16, 2005. The length of the article is 569 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Fibroids; Prevention. Publication: NWHRC Health Center - Fibroids (Pamphlet) Date: March 16, 2005 Publisher: Thomson Gale Page: NA Distributed by Thomson Gale |
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