Characteristic pathological findings in reflux esophagitisAugust 10, 2009Recently, the number of patients with GERD has increased in Japan. However, there have been few reports about the pathological findings in the esophageal squamous epithelium, and there are differing opinions among pathologists about the findings considered characteristic of chronic reflux esophagitis.  Dr. Daisuke Asaoka and his colleagues from Juntendo University (Japan) used a rat model of chronic acid-reflux esophagitis to explore the esophageal mucosal damage macroscopically and microscopically throughout the entire esophagus, including the upper esophagus close to the hypopharynx, and to investigate the protective effects of ecabet sodium (ES) on the esophageal mucosa. This will be published on July 28, 2009 in the World Journal of Gastroenterology, Their research revealed that epithelial thickening occurs at the same time as inflammatory cell infiltration in the middle to lower esophagus in chronic acid-reflux esophagitis. Furthermore, they demonstrated that inflammatory cells infiltrated the epithelium of the upper esophagus close to the hypopharynx, where there was no evidence of ulcers. These findings suggested that the reflux of gastric juice can extend to the upper esophagus close to the hypopharynx. Moreove, the research also demonstrated that ES inhibited the epithelial thickening of the lower and middle esophagus, which suggested that ES may play a useful defensive role in the prevention of reflux esophagitis. World Journal of Gastroenterology |
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| Related Esophagus Current Events and Esophagus News Articles Reflux esophagitis due to immune reaction, not acute acid burn, UT Southwestern researchers report Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study. African-Americans with colorectal cancer have poorer outcomes, lower survival rates New research published in the November issue of the Journal of the American College of Surgeons shows that African-American patients with colorectal cancer are more likely to be diagnosed with advanced disease and are less likely to undergo surgical procedures compared with Caucasians, suggesting that improvements in screening and rates of operation may reduce differences in colorectal cancer outcomes for African-Americans. California Academy of Sciences becomes first aquarium in US to breed dwarf cuttlefish Anchored to an algae-covered rock in a 120-gallon tank at the California Academy of Sciences' Steinhart Aquarium, a cluster of inky-colored cuttlefish eggs is beginning to swell-evidence of success for the Academy's new captive breeding program for dwarf cuttlefish, Sepia bandensis. Study of concurrent radiotherapy, chemotherapy shows promise in small cell lung cancer Treating limited stage small cell lung cancer(LSCL) with a combination of accelerated high-dose radiotherapy and chemotherapy has shown encouraging results. Surgeons at Boston Medical Center offering new procedure for acid reflux/GERD Boston Medical Center (BMC) surgeons are now offering patients an incisionless alternative to laparoscopic and traditional surgery for treatment of acid reflux or GERD. Barrett's esophagus patients have same survival rates as general population New Mayo Clinic research has found that survival rates of patients with Barrett's esophagus, which can be a precursor for esophageal cancer, are no different than the survival rates for the general population. UF scientists discover new explanation for controversial old patient-care technique You might not know what it's called, but if you've had general anesthesia before surgery, especially after an accident, it is likely you have received Sellick's maneuver. Many patients with sleep apnea also suffer from GI tract conditions Patients who suffer from obstructive sleep apnea (OSA) also tend to have additional gastrointestinal (GI) tract conditions, such as gastric reflux and hiatal hernia, which form at the opening in your diaphragm where your food pipe (esophagus) joins your stomach. Artificial intelligence helps diagnose cardiac infections Mayo Clinic researchers say that "teachable software" designed to mimic the human brain may help them diagnose cardiac infections without an invasive exam. GERD negatively impacts sleep quality, results in considerable economic burden There has been much debate about the relationship between gastroesophageal reflux disease (GERD) and sleep. More Esophagus Current Events and Esophagus News Articles |
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