 |
|
New groundbreaking treatment for oxygen-deprived newborns
August 11, 2009Until now immediate cooling of the newborn infant was the only treatment that could possibly prevent brain damage following oxygen deprivation during delivery. New research findings from the Sahlgrenska Academy and Sahlgrenska University Hospital, in collaboration with Zhengzhou University in China, open up the possibility of a new and effective treatment that can be started as late as two days after birth.
This new treatment involves newborn infants being given a two-week course of injections of erythropoietin, a hormone that stimulates the formation of red blood cells.
"For the first time we can demonstrate that it is possible to influence the brain damage occurring as a result of oxygen deprivation during delivery considerably later than the six-hour window of opportunity for treating with cooling," says Klas Blomgren, professor of paediatrics at the Sahlgrenska Academy and specialist at Queen Silvia Children's Hospital.
The research findings, which are presented in the latest issue of the highly-respected medical journal Pediatrics, are the result of cooperation between Swedish, Austrian and Chinese researchers. The study treated just over 150 term newborn infants, half of whom were given small doses of erythropoietin every other day. Once the children reached the age of eighteen months, their neurological condition was assessed.
"Only half as many of the children treated with erythropoietin had developed a severe neurological functional disability or had died of their injuries. Thus the hormone treatment improves the prognosis considerably in the longer perspective," says Blomgren.
The children in the study had suffered moderate or severe hypoxic-ischemic encephalopathy (HIE) at birth, but it was only children with moderate HIE that were helped by this hormone treatment.
"We believe that erythropoietin has a regenerative and stimulating effect on recovery and on brain development following the injury. This appears to be a safe treatment, almost without side effects, and it is also cheaper and technically simpler to administer in comparison with cooling. This means that the treatment can be given a wide distribution, and can be used even in developing countries," says Blomgren.
University of Gothenburg, Sweden
The research findings, which are presented in the latest issue of the highly-respected medical journal Pediatrics, are the result of cooperation between Swedish, Austrian and Chinese researchers. The study treated just over 150 term newborn infants, half of whom were given small doses of erythropoietin every other day. Once the children reached the age of eighteen months, their neurological condition was assessed.
"Only half as many of the children treated with erythropoietin had developed a severe neurological functional disability or had died of their injuries. Thus the hormone treatment improves the prognosis considerably in the longer perspective," says Blomgren.
The children in the study had suffered moderate or severe hypoxic-ischemic encephalopathy (HIE) at birth, but it was only children with moderate HIE that were helped by this hormone treatment.
"We believe that erythropoietin has a regenerative and stimulating effect on recovery and on brain development following the injury. This appears to be a safe treatment, almost without side effects, and it is also cheaper and technically simpler to administer in comparison with cooling. This means that the treatment can be given a wide distribution, and can be used even in developing countries," says Blomgren.
University of Gothenburg, Sweden
Oxygen Deprivation Current Events and Oxygen Deprivation News RSSBreathing technique can reduce frequency, severity of asthma attacks
As the health care reform debate turns to cutting costs and improving treatment outcomes, two professors at Southern Methodist University in Dallas are expanding a study that shows promise for reducing both the expense and suffering associated with chronic asthma.
Piece from childhood virus may save soldiers' lives
A harmless shard from the shell of a common childhood virus may halt a biological process that kills a significant percentage of battlefield casualties, heart attack victims and oxygen-deprived newborns.
Simple drug treatment may prevent nicotine-induced SIDS: Study
A new study has identified a specific class of pharmaceutical drugs that could be effective in treating babies vulnerable to Sudden Infant Death Syndrome (SIDS), because their mothers smoked during pregnancy.
Researchers identify genetic switch critical for cell survival in hypoxia
Researchers at the University of California, San Diego School of Medicine have identified a critical metabolic "switch" in fruit flies that helps oxygen-deprived cells survive.
Erectile dysfunction related to sleep apnea may persist, but is treatable
For sufferers of sleep apnea, erectile dysfunction (ED) is often part of the package. New research indicates that ED in cases of obstructive sleep apnea syndrome (OSAS) may be linked to the chronic intermittent hypoxia-oxygen deprivation- (CIH) that patients with OSAS experience during episodes of obstructed breathing.
Human embryonic stem cell secretions minimized tissue injury after heart attack
A novel way to improve survival and recovery rate after a heart attack was reported in the journal Stem Cell Research by scientists at Singapore's Institute of Medical Biology (IMB) and Bioprocessing Technology Institute (BTI) and The Netherlands' University Medical Center Utrecht.
Resuscitation technique after brain injury may do more harm than good
The current standard practice of giving infants and children 100 percent oxygen to prevent brain damage caused by oxygen deprivation may actually inflict additional harm, researchers at UT Southwestern Medical Center have found.
Researchers link master regulator of innate immunity to the hypoxic response
Survival of all animals depends on their ability to withstand microbial infections and adapt to fluctuations in oxygen concentrations.
Another way to grow blood vessels
Researchers at Dana-Farber Cancer Institute have found a previously unknown molecular pathway in mice that spurs the growth of new blood vessels when body parts are jeopardized by poor circulation.
Children's Hospital researchers identify molecular 'switch' that could save very young lives
A team of researchers at Children's Hospital of Pittsburgh of UPMC have identified a molecular "switch" that, when blocked, may help reverse necrotizing enterocolitis (NEC), a leading cause of death in premature infants.
More Oxygen Deprivation Current Events and Oxygen Deprivation News Articles
 |
Tissue Oxygen Deprivation (Lung Biology in Health and Disease) by Gabriel Haddad (Editor) Detailing the importance of hypoxia in the expression, genesis, and propagation of human illness--this state-of-the-art reference summarizes current knowledge of responses to hypoxia in a variety of organ systems and in a number of vital processes common to all systems--addressing the effect of oxygen deprivation on fundamental processes such as cellular energetics, ion transport, and receptor function. |
 |
Oxygen Deprivation DrBior (Primary Contributor) |
 |
Fire Sense 60269 Tabletop LPG Heater with Oxygen Deprivation Sensor - Copper Plated Steel by Fire Sense If you want to have a party outside after the summer is over, choose the Fire Sense Copper Finish Table Top Patio Heater. It provides warmth and creates an ambiance in your backyard or patio. It sits on your table emitting incredibly safe heat. It is ODS compliant and has an oxygen depletion sensor. Also for your safety, this heater is CSA approved. The heat output of the Fire Sense Copper Finish Table Top patio heater can be adjusted to 10,000 BTUs. The outdoor temperature is raised ten to twenty five degrees. It has an easy one step Piezo igniter and stainless steel burners and heating grid. It uses a standard one pound propane cylinder that is not included. An auto shut off tilt valve is included with the Fire Sense Copper Finish Table Top patio heater. It also has a safety grill... |
|
Plant Life Under Oxygen Deprivation: Ecology, Physiology and Biochemistry by M. B. Jackson (Editor) | |
|
GA: failure to monitor infant-neurological injury: nurse not liable for deprivation of oxygen, etc.(Legal Case Briefs for Nurses): An article from: Nursing Law's Regan Report by A. David Tammelleo (Author) This digital document is an article from Nursing Law's Regan Report, published by Medica Press, Inc. on December 1, 2003. The length of the article is 624 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: GA: failure to monitor infant-neurological injury: nurse not liable for deprivation of oxygen, etc.(Legal Case Briefs for Nurses) Author: A. David Tammelleo Publication: Nursing Law's Regan Report (Newsletter) Date: December 1, 2003 Publisher: Medica Press, Inc. Volume: 44 Issue: 7 Page: 3(1) Distributed by Thomson... | |
|
The Psychological Effects of Oxygen Deprivation (Anoxemia) on Human Behavior. by Ross A Mcfarland (Author) | |
 |
Oxygen Deprivation Splub (Primary Contributor) |
|
The structural changes produced in the human brain by oxygen deprivation (anoxemia) and their pathogenesis, by John Chornyak (Author) | |
|
The effects of oxygen deprivation (high altitude) on the human organism (Technical development report) by Ross A McFarland (Author) | |
 |
Fire Sense 60262 Tabletop LPG Heater with Oxygen Deprivation Sensor - 304 Stainless Steel by Fire Sense The Fire Sense Stainless Steel Table Top Patio Heater not only warms up your outdoor gatherings, but also enhances the d?cor of your patio or backyard. The heat output can be adjusted to 10,000 BTUS and the approximate consumption rate is three hours per disposable LPG cylinder. For this heater, a standard one pound propane cylinder is used but not included. With the Fire Sense Stainless Steel Table Top patio heater, your outdoor temperature will be raised by ten to twenty five degrees. It has a one step ignition Piezo igniter. The construction, burners and heating grid are made of stainless steel. It is lightweight and portable. The Stainless Steel Table Top patio heater has a variety of safety features as well. It has an auto shut off tilt valve and a safety grill guard. It is ODS... |
| © 2009 BrightSurf.com |