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New treatment in sight for ovarian cancer
August 31, 2009In the future, women with metastatic ovarian cancer could be treated with a radioactive substance that can seek and destroy tumour cells. An initial study in patients conducted jointly by the Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital has found that the treatment has no unwanted side-effects.
"Our research team has long hoped to be able to target radiotherapy in this way," says oncologist Hĺkan Andersson from Sahlgrenska University Hospital, who is leading the research alongside professor Ragnar Hultborn from the Sahlgrenska Academy and radiation physicist Lars Jacobsson.
The aim of this initial patient study, just published in the Journal of Nuclear Medicine, was to study the substance's distribution in the body and any side-effects in nine women with ovarian cancer.
The new treatment has been developed jointly over a number of years by researchers at the Sahlgrenska Academy and Sahlgrenska University Hospital. The treatment entails injecting the patient with a radioactive isotope bound to carrier molecules. This complex has the ability to bind to structures on the surface of tumour cells where the isotope emits alpha particles with such a short range that only the very nearest tumour cells' DNA is destroyed. The injection is administered straight into the abdominal cavity.
"We have previously seen that mice with ovarian cancer given this treatment are generally cured without serious side-effects, so we hope that this will become an established and effective treatment for women with metastatic ovarian cancer," says Ragnar Hultborn, professor of oncology at the University of Gothenburg's Sahlgrenska Academy. "But it will still be several years of development."
The research is being funded partly by the Swedish Research Council and the Swedish Cancer Society.
"In our next study, 80 women with ovarian cancer will receive this treatment as a supplement to their ordinary treatment so that we can scientifically test whether the effect is as good in real patients as the animal studies indicate," Hĺkan Andersson says.
University of Gothenburg
Ovarian Cancer Current Events and Ovarian Cancer News RSSFDA approved leukemia drugs shows promise in ovarian cancer cells
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA's Jonsson Comprehensive Cancer Center found.
American Dietetic Association Releases Updated Position Paper Promoting and Supporting Breastfeeding
The American Dietetic Association has released an updated position paper on breastfeeding that details health benefits for both infants and mothers and encourages promotion of breastfeeding whenever possible.
Metals could forge new cancer drug
Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds.
Breast cancer patients with high risk gene diagnosed 6 years earlier than generation before
Women with a deleterious gene mutation are diagnosed with breast cancer six years earlier than relatives of the previous generation who also had the disease and/or ovarian cancer, according to new research from The University of Texas M. D. Anderson Cancer Center.
Cancer Predisposition From Gene Variant Shows Strong Gender Bias
Cancer predisposition resulting from the presence of a specific gene variant shows a strong gender bias, researchers at the University of Cincinnati (UC) have demonstrated.
Medications Effective in Reducing Risks for Breast Cancer Can Also Cause Serious Side Effects
Three drugs that reduce a woman's chance of getting breast cancer also have been shown to cause adverse effects, according to a new report from the Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Health & Human Services.
Scientists from University of Hawaii at Manoa find genetic marker
A new genetic marker associated with ovarian cancer risk was recently discovered by an international research group, led by scientists from the Cancer Research Genetic Epidemiology Unit in the United Kingdom.
Young early stage ovarian cancer patients can preserve fertility
A new study finds that young women with early-stage ovarian cancer can preserve future fertility by keeping at least one ovary or the uterus without increasing the risk of dying from the disease.
Estrogen-Dependent Switch Tempers Killing Activity of Immune Cells
The sex hormone estrogen tempers the killing activity of a specific group of immune cells, the cytotoxic T cells (CTLs), which are known to attack tumor cells and cells infected by viruses.
Women often opt to surgically remove their breasts, ovaries to reduce cancer risk
Many women at high risk for breast or ovarian cancer are choosing to undergo surgery as a precautionary measure to decrease their cancer risk.
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Beating Ovarian Cancer: How To Overcome The Odds And Reclaim Your Life by Chris Bledy (Author) A diagnosis of Ovarian Cancer does not have to be a death sentence. Recent advances in medicine have made this once incurable disease treatable and manageable. You can beat advanced and even recurring, ovarian cancer. Simple but significant lifestyle changes can produce big results when it comes to healing. |
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Ovarian Cancer Awareness "Unite to Fight" Wristband Adult Size by sci Ovarian Cancer Awareness "Unite To Fight" Wristband adult size |
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Ovarian Cancer Awareness 8" Ribbon Car Magnet by sci Ovarian Cancer Awareness 8" Ribbon Car Magnet |
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A Guide to Survivorship for Women with Ovarian Cancer (A Johns Hopkins Press Health Book) by F. J. Montz MD KM FACOG FACS (Author), Robert E. Bristow MD FACOG (Author), Paula J. Anastasia RN MN OCN (Assistant) This comprehensive guide to ovarian cancer offers a wealth of information to ease the physical, emotional, and psychic suffering of women with the disease. The authors -- two Johns Hopkins gynecologic oncologists and a gynecologic-oncology clinical nurse -- put particular emphasis on the concept of "survivorship," or living life well in the face of daunting uncertainties. They stress the importance of self-determination: the right of each patient to be informed, involved, and in control of her care. Up-to-date information on diagnosis and treatment, including surgery, chemotherapy, radiation, pain management, and alternative therapies, forms the core of the book. But the authors' immense clinical experience also means they understand what women worry about and care about, and... |
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L'Oréal Paris Color of Hope OCRF (Ovarian Cancer Research Fund) Fundraising Sterling Silver Pavé CZ Bracelet by Netaya Sterling beauty with an equally beautiful message. Its new, its exclusive and its absolutely beautiful. LOreal Paris is proud to present the Color of Hope Bracelet, a fundraising campaign, with 100% of all net profits ($5.00 per bracelet) benefiting The Ovarian Cancer Research Fund (OCRF). Whether viewed as a circle representing life, endurance, love or seen as an "O" for ovarian cancer, the bracelet is a simple way for women everywhere to visibly and tangibly help in the fight against one of the world's most deadly of women's cancers. The exclusive sterling silver Color of Hope bracelet features a rolo design chain with an "O" toggle clasp, adorned with pave cubic zirconias to give a beautiful brilliance. And to ensure that all women can adorn their wrists, the bracelet... |
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Ovarian Cancer Awareness Teal Ribbon Crystal Heart Necklace by CharmingChick This is a beautiful new teal ribbon heart charm necklace that is the perfect way to show your support for Ovarian Cancer Awareness. The pendant measures about 5/8 of an inch tall and is made of genuine sterling silver. It has stunning teal Swarovski Crystal embedded in the front. Box chain measures about 16 inches long. This teal ribbon necklace would make a great gift or is a wonderful way to remember a loved one with Ovarian Cancer. |
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100 Questions & Answers About Ovarian Cancer, Second Edition by Don S. Dizon (Author) Whether you're a newly diagnosed ovarian cancer patient, a survivor, or a friend or relative of either, this book offers help. Completely updated, the new second edition of 100 Questions & Answers About Ovarian Cancer gives you authoritative, practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. Written by a gynecologic oncologist and a gynecologic surgeon, with actual patient commentary, this book is an invaluable resource for anyone coping with the physical and emotional turmoil of this frightening disease. |
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100 Pack Teal Blue Ribbon Temporary Tattoos for Ovarian Cervical Uterine Cancer Awareness by Palmetto Fundraising Show your courage and support! These teal ribbon tattoos are perfect for your next awareness event. These tattoos make great inspirational giveaways. 100 tattoos per package. Teal ribbon design with clear sides. Approximately 1.5" x 2". These cancer awareness favors are perfect for your awareness fundraisers or event. |
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L'Oreal Paris Hope Necklace by Netaya The L'Oreal Paris Hope Necklace is a simple way for women everywhere to visibly and tangibly help in the fight against one of the most deadly women's cancers. The necklace was designed by 2008 Swarovski Award for Accessory Design recipient Philip Crangi and features a double eternity ring design of cubic zirconia set in sterling silver. One ring is worn for remembrance and one ring is worn as a symbol of hope for the future. The two eternity rings are free floating and suspended from an 18" rolo link chain. Each ring is comprised of 21 channel set, 2mm brilliant cubic zirconias. This necklace normally retails for $99 but is being offered for only $29.95 (plus $5.95 s&h) to support ongoing research to defeat this dreadful disease. Net profits (five dollars per sale) will benefit... |
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