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Toward a nanomedicine for brain cancer
September 10, 2009In an advance toward better treatments for the most serious form of brain cancer, scientists in Illinois are reporting development of the first nanoparticles that seek out and destroy brain cancer cells without damaging nearby healthy cells. The study is scheduled for the Sept. 9 issue of ACS' Nano Letters, a monthly journal.
Elena Rozhkova and colleagues note the pressing need for new ways to treat the disease, glioblastoma multiforme (GBM), which often causes death within months of diagnosis. Recent studies show that titanium dioxide nanoparticles, a type of light-sensitive material widely used in sunscreens, cosmetics, and even wastewater treatment, can destroy some cancer cells when the chemical is exposed to ultraviolet light. However, scientists have had difficulty getting nanoparticles, each about 1/50,000th the width of a human hair, to target and enter cancer cells while avoiding healthy cells.
The scientists' solution involves chemically linked titanium dioxide nanoparticles to an antibody that recognizes and attaches to GMB cells. When they exposed cultured human GMB cells to these so-called "nanobio hybrids," the nanoparticles killed up to 80 percent of the brain cancer cells after 5 minutes of exposure to focused white light. The results suggest that these nanoparticles could become a promising part of brain cancer therapy, when used during surgery, the researchers say.
American Chemical Society
American Chemical Society
Brain Cancer Current Events and Brain Cancer News RSSMetabolite common among cancers
A study published online on February 8 in the Journal of Experimental Medicine (www.jem.org) reports that several distinct mutations found in a subset of patients with acute myelogenous leukemia (AML) result in excess production of the same metabolite.
The Cancer Genome Atlas identifies distinct subtypes of deadly brain cancer
The most common form of malignant brain cancer in adults, glioblastoma multiforme (GBM), is not a single disease but appears to be four distinct molecular subtypes, according to a study by The Cancer Genome Atlas (TCGA) Research Network.
More accurate diagnosis for leading cancer killer in children may be possible
Brain cancer is the leading cause of cancer death in children. Now a more accurate diagnosis of childhood brain cancers may soon be possible, according to researchers at Huntsman Cancer Institute (HCI) at the University of Utah. The information is published online today in the journal Cancer Research.
Study sheds light on role of stem cells in children's brain tumor
New research from scientists at Queen Mary, University of London shows how the most common type of children's brain cancer can arise from stem cells.
Discovery at JGH opens door to new treatments for prostate, brain and skin cancers
Researchers at the Lady Davis Institute for Medical Research of the Jewish General Hospital and McGill University in Montreal have discovered a previously unsuspected link between two different genetic pathways which suppress the growth of cancer tumours.
Cell phone exposure may protect against and reverse Alzheimer's disease
The millions of people who spend hours every day on a cell phone may have a new excuse for yakking. A surprising new study in mice provides the first evidence that long-term exposure to electromagnetic waves associated with cell phone use may actually protect against, and even reverse, Alzheimer's disease.
Experimental drug shows promise against brain, prostate cancers
An experimental drug currently being tested against breast and lung cancer shows promise in fighting the brain cancer glioblastoma and prostate cancer, researchers at UT Southwestern Medical Center have found in two preclinical studies.
Targeting brain cancer cell metabolism may provide new treatment
Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according to a first-of-its-kind study by researchers at UCLA's Jonsson Comprehensive Cancer Center.
Small addition to cancer drug may make big difference
University of Florida researchers have found a way to use just a fraction of the normal dosage of a highly toxic, debilitating chemotherapy drug to achieve even better results against colon cancer cells.
Discovery makes brain tumor cells more responsive to radiation
Duke University Medical Center researchers have figured out how stem cells in the malignant brain cancer glioma may be better able to resist radiation therapy.
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Living with a Brain Tumor: Dr. Peter Black's Guide to Taking Control of Your Treatment by Peter Black (Author) Each year, 100,000 people in the United States are diagnosed with a brain tumor. With his new book, Dr. Peter Black fills a gap in the lay readership, providing an accessible medical resource for adult patients and their families. Dr. Black, who has operated on more than 3,000 patients with brain tumors, is uniquely qualified to discuss both clinical treatment of and research into brain tumors. This invaluable resource tells patients everything they need to know to understand and address their diagnosis, in a four-part structure: • “What is a Brain Tumor?" provides straightforward information about how brain tumors are diagnosed, the different types of tumors and how they develop, and where to go for treatment. • “Coping with Shock” addresses the emotional... |
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Curveball: When Life Throws You a Brain Tumor by Liz Holzemer (Author) Life seemed idyllic for thirty-two-year-old Liz Holzemer. Wife of Major League Baseball pitcher Mark Holzemer, Liz was enjoying a successful career as a journalist when an MRI revealed a baseball-size brain tumor she soon found out was called meningioma. Told with clarity and unwavering humor, this book is an inspirational and informative account of one woman’s battle for her life. It shows how she emerged from this frightening diagnosis and two brain surgeries retaining her remarkable spirit of survival and renewed sense of purpose and hope. With practical information about meningioma and brain surgery, Curveball is a manual for people who face life-altering challenges and is also proof that one need not fight such battles alone. |
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The NewsHour Reports on Brain Research, Treatment and Disease Starring: Betty Ann Bowser; Dr. Mickey Collins; Dr. Mark Lovell; Susan Dentzer; Dr. Michael Simberkoff; Paul Allen Also With: MacNeil / Lehrer Productions (Producer) The NewsHour reports on brain research and treatments for brain injury and disease. Included are segments featuring research on diagnosing and treating concussion; traumatic brain injury treatment of veterans; the development of a brain mapping tool; research on cell phone use and its effects on the brain and research that demonstrates the human body is able to produce new brain cells. This product is manufactured on demand using DVD-R recordable media. Amazon.com's standard return policy will apply. |
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Surviving Terminal Cancer: Clinical Trials, Drug Cocktails, and Other Treatments Your Oncologist Won't Tell You About by Ben A. Williams (Author) (Fairview Press) Univ. of California, San Diego. Consumer text explains how patients can improve their odds for survival by demanding control over their health care, research conventional and alternative treatments, creating their own treatment strategy, and using the Internet to learn of new medical advances. Softcover. |
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Silver Swarovski Crystals Ribbon Pin Brooch: Brain Cancer & Brain Disorder or Disability Awareness by PSDZ Ribbon Pin Brooch is set with lots of genuine, sparkling Swarovski Crystals White Height: 1.5 Inch Width: .75 Inch Each of these items has been hand enameled by skilled artisans, and set with genuine, Swarovski Crystals. The frame is crafted from fine pewter. Our Collection adds the definitive touch to any gift-giving occasion. Also, this collection has been issued in limited editions and each piece will become a valuable keepsake to its owner, for years to come. Please see other items in this collection in our Amazon Store: PSDZ. Jewelry Boxes, Business Card Holders, Music Boxes, Mezuzahs, Crosses, Picture Frames, Faberge style Egg Boxes, Candle Holders, Clocks, Holiday Boxes, Decorations, Perfume Bottles, and more! Please Note: Due To Time Consuming Customs Forms, We Ship... |
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Cancer Be Gone Guided imagery CD taps into the immense power of the mind to enhance comfort, healing, an optimistic attitude and positive expectations. Metaphor of "cancer as weeds in a garden that are easily managed". |
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