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HBV genotype B/B3 and C/C1 are the major genotypes in Indonesia?
September 16, 2009Previous studies revealed that HBV genotypes as well as mutations in the core promoter, precore or HBx gene have been shown to have an association with the clinical outcome of liver disease, however, this is still controversial. It is likely that this depends on the HBV genotype distribution in certain region. So far, there is no such data from Indonesia, which is a big country with a big population and a relatively high HBV carrier rate.
A research article to be published on August 28, 2009 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Utama from Mochtar Riady Institute for Nanotechnology, used samples from HBV-associated liver disease patients [chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC)]collected from several centers, to study the association between HBV genotype and mutations and clinical outcome of liver disease.
The study demonstrated that only HBV genotype B and C were detected among HBV-associated liver disease patients in Indonesia, and genotype B was predominant. It was found that HBV genotype, as well as the serotype, might not be associated with an increased risk of HCC. The double mutation (A1762T/G1764A) was associated with progression of liver disease, while T1753V mutation could be used as an indicator of liver cirrhosis rather than HCC.
World Journal of Gastroenterology
World Journal of Gastroenterology
Liver Disease Current Events and Liver Disease News RSSLargest-ever database for liver proteins may lead to treatments for hepatitis
Scientists at a group of 11 research centers in China are reporting for the first time assembly of the largest-ever collection of data about the proteins produced by genes in a single human organ.
Alcohol Tolerance Switch Found in Fruit Flies
Researchers at North Carolina State University have found a genetic "switch" in fruit flies that plays an important role in making flies more tolerant to alcohol.
Scientists develop novel method to generate functional hepatocytes for drug testing
Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell (iPSC) technology.
UCSD researchers pave the way for effective liver treatments
A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease.
Governor recognizes stem cell research at Einstein
Albert Einstein College of Medicine of Yeshiva University hosted a roundtable discussion on stem cell research with New York Governor David A. Paterson today.
Liver cells grown from patients' skin cells
Scientists at The Medical College of Wisconsin in Milwaukee have successfully produced liver cells from patients' skin cells opening the possibility of treating a wide range of diseases that affect liver function.
Metabolic syndrome linked to liver disease in obese teenaged boys
Researchers studying a large sample of adolescent American boys have found an association between metabolic syndrome, which is a complication of obesity, and elevated liver enzymes that mark potentially serious liver disease.
Penn State College of Medicine research isolates liver cancer stem cells prior to tumor formation
Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer.
Genetic hint for ridding the body of hepatitis C
More than seventy percent of people who contract Hepatitis C will live with the virus that causes it for the rest of their lives and some will develop serious liver disease including cancer.
Second-hand smoking results in liver disease, study finds
A team of scientists at the University of California, Riverside has found that even second-hand tobacco smoke exposure can result in nonalcoholic fatty liver disease (NAFLD), a common disease and rising cause of chronic liver injury in which fat accumulates in the liver of people who drink little or no alcohol.
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PetAlive Immunity and Liver Support for Protection Against Disease (60 Caps) by PetAlive PetAlive Immunity and Liver Support capsules contain a combination of especially selected herbs known for their ability to cleanse and purify the system, improve immune functioning and support liver health. Used as a general tonic or to protect against disease, Immunity and Liver Support capsules are also very effective during convalescence and can help your pet in the recovery phase after illness. Use PetAlive Immunity and Liver Support to boost immune functioning and resistance against disease and infection, including viral and bacterial infection; improve liver health and functioning and aid in the elimination of systemic toxins; act as a tonic for the lymphatic system; help to counter the harmful effects of frequent vaccinations and antibiotic treatment; promote and speed up healing... |
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Liver Disease Awareness Ribbon Mouse Pad by MyHeritageWear.com The Liver Disease Ribbon proudly displayed on a mouse pad. There is no better way to achieve awareness for the meaning of the Liver Disease Ribbon than to display it on your mouse pad for everyone to see. The mouse pad measures at 9.25 x 7.75, it is machine washable, and the colors will not fade or run. Start gaining awareness today by presenting your Liver Disease Ribbon mouse pad at work or at home. It is certain to keep your mouse rolling in style all while gaining support and awareness! |
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Liver Disease BreakBeater (Primary Contributor) |
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Resource 2.0, Vanilla (formerly Novasource 2.0) 8 oz, 27/Case by Novartis Resource 2.0 is a calorically-dense, high nitrogen, complete liquid formula, specifically designed for the management of fluid restriction and elevated nutritional needs. It is designed with a reduced level of sodium which is often indicated for patients requiring fluid restriction. Resource 2.0 has a mild vanilla flavor and is appropriate for supplemental feeding including medication pass programs, as well as for total enteral feeding. Primary Indications: Medication pass programs, Wound prevention and treatment programs, Fluid restricted/volume sensitive patients, Congestive Heart Failure, Liver Disease with Ascites, Pulmonary Edema, Respiratory Disease, Shortened feeding schedules, Elevated Calorie and Protein Need |
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