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Despite ongoing safety concerns, study finds adverse reactions from contrast agents rarely occur
September 21, 2009Iodinated and Gadolinium based contrast agents, frequently used during computed tomography (CT) and MRI scans to aid in the imaging process, are associated with a very low rate of adverse effects, according to a large cohort study published in the October issue of the American Journal of Roentgenology (AJR).
The study, performed at the Mayo Clinic in Rochester, MN, included a total of 456,930 contrast doses administered. "Only 522 cases of adverse effects were identified," said Christopher H. Hung, MD, lead author of the study. "The overwhelming majority of adverse effects were mild, represented with nausea and vomiting and mild rash. Only 16 cases necessitated transfer for further observation and treatment," he said.
"Contrast agents are very safe to use and they are often essential in aiding the diagnosis of CT and MR studies. As our study suggests, with the advent of newer contrast agents we have been able to improve their power-ability and safety profile," said Dr. Hunt.
"While contrast reactions can occur, it is important to note that they are rarely severe. Most of the reactions we saw in our study were mild and did not require treatment other than observation and supportive care," he said.
American Roentgen Ray Society
"While contrast reactions can occur, it is important to note that they are rarely severe. Most of the reactions we saw in our study were mild and did not require treatment other than observation and supportive care," he said.
American Roentgen Ray Society
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Getting better visualization of joint cartilage through cationic CT contrast agents
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Twinkling nanostars cast new light into biomedical imaging
Purdue University researchers have created magnetically responsive gold nanostars that may offer a new approach to biomedical imaging.
Even at High Doses, Gadolinium-Based Contrast Agents Cannot by Themselves Cause Patients to Develop Nephrogenic Systemic Fibrosis
Even at very high doses, gadolinium-based contrast agents alone are not sufficient to cause nephrogenic systemic fibrosis (NSF) in patients with kidney problems.
Sodium bicarbonate reduces incidence of contrast-induced nephropathy
A meta-analysis of 17 randomised controlled trials has shown that pre-procedural treatment with sodium bicarbonate based hydration is the optimal treatment strategy to prevent contrast-induced nephropathy (CIN).
Fluorescent cancer cells to guide brain surgeons
Gliomas are malignant brain tumors that arise from glial (supporting) cells of the brain. Gliomas are often resistant to chemotherapy.
Seaweed and fireflies brew may guide stem cell treatment for peripheral artery disease
An unlikely brew of seaweed and glow-in-the-dark biochemical agents may hold the key to the safe use of transplanted stem cells to treat patients with severe peripheral arterial disease (PAD), according to a team of veterinarians, basic scientists and interventional radiologists at Johns Hopkins.
Novel technique changes lymph node biopsy, reduces radiation exposure in breast cancer patients
Information obtained from a new application of photoacoustic tomography (PAT) is worth its weight in gold to breast cancer patients.
Researchers create smaller, brighter probe tailored for molecular imaging and tumor targeting
Researchers have developed a new generation of microscopic particles for molecular imaging, constituting one of the first promising nanoparticle platforms that may be readily adapted for tumor targeting and treatment in the clinic.
Late-breaking results of clinical trial on therapeutic endovascular cooling reported at TCT 2008
Late-breaking results from the COOL RCN (COOLing to Prevent Radio Contrast Nephropathy in Patients Undergoing Diagnostic or Interventional Catheterization) Trial were presented during the 20th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation (CRF).
More Contrast Agents Current Events and Contrast Agents News Articles
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Acoustic Characterization of Contrast Agents for Medical Ultrasound IMaging by Lars Hoff (Author) Contrast agents for medical ultrasound imaging is a field of growing interest. A large amount of literature has been published on the medical applications of such contrast agents. However, there is no textbook giving a broad overview of the physics and acoustics of the agents. This monograph aims to fill this gap. The book is written by a physicist, from a physics point of view, and it tries to draw links from the physics and acoustics to the medical imaging methods, but medical applications are mainly included for background information. The book consists of nine chapters. The first three chapters give a broad overview of the acoustic theory for bubble--sound interaction, both linear and nonlinear. Most contrast agents are stabilized in a shell, and this shell can have a... |
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Ultrasound Contrast Agents: Basic Principles and Clinical Applications by Barry B. Goldberg (Author), Joel S Raichlen (Author), Flemming Forsberg (Author) Thomas Jefferson Univ., Philadelphia, PA. Discusses the underlying principles governing ultrasound contrast agents and the clinical utility of the ultrasound agent. Previous edition: c1997. Illustrations in a variety of formats are included. |
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Pharmaceuticals in Medical Imaging: Radiopaque Contrast Media, Radiopharmaceuticals, Enhancement Agents for Magnetic Resonance Imaging and Ultrasoun by Dennis P. Swanson (Author), Henry M. Chilton (Author), James H. Thrall (Author) | |
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Contrast Agents III: Radiopharmaceuticals - From Diagnostics to Therapeutics (Topics in Current Chemistry) (v. 3) by Werner Krause (Editor) Berlex International Project Management Oncology, Montville, NJ. Provides information on radiopharmaceutical contrast agents and their new developments used as therapeutic drugs. Topics covered include new organometallic technetium complexes and radiopharmaceuticals for positron emission tomography. |
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Preparation and Characterization of Hollow Microcapsules for Use as Ultrasound Contrast Agents.: An article from: Polymer Engineering and Science by Padma Narayan (Author), Margaret A. Wheatley (Author) This digital document is an article from Polymer Engineering and Science, published by Society of Plastics Engineers, Inc. on November 1, 1999. The length of the article is 7084 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Preparation and Characterization of Hollow Microcapsules for Use as Ultrasound Contrast Agents. Author: Padma Narayan Publication: Polymer Engineering and Science (Refereed) Date: November 1, 1999 Publisher: Society of Plastics Engineers, Inc. Volume: 39 Issue: 11 Page: 2242 Distributed by Thomson... | |
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Radiographic Contrast Agents by Jovitas Skucas (Editor) | |
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Contrast Agents II (Topics in Current Chemistry) (Pt. 2) by Werner Krause (Editor) The present volume on optical, ultrasound, X-ray and radiopharmaceutical contrast agents is the second in a series on diagnostics following a volume that was exclusively dedicated to magnetic resonance imaging. This volume covers compounds from four different imaging modalities starting with the most recent technology, optical imaging, followed by diagnostic ultrasound and the still dominant albeit more than one hundred year-old X-ray technique and concluding with radiopharmaceutical contrast agents. Whereas contrast agents for optical imaging are not yet widely used - except for some dedicated techniques such as liver function tests - ultrasound is by now a well established procedure. However, since the machines are meanwhile so excellent - and nevertheless still improving -,... |
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Standards for Iodinated Intravascular Contrast Agent Administration to Adult Patients by Royal College of Radiologists (Publisher) | |
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Fibrosis risk added to contrast agents' labels.(News): An article from: Family Practice News by Elizabeth Mechcatie (Author) This digital document is an article from Family Practice News, published by Thomson Gale on June 15, 2007. The length of the article is 618 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Fibrosis risk added to contrast agents' labels.(News) Author: Elizabeth Mechcatie Publication: Family Practice News (Magazine/Journal) Date: June 15, 2007 Publisher: Thomson Gale Volume: 37 Issue: 12 Page: 6(1) Distributed by Thomson... | |
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Nephrogenic fibrosing dermopathy associated with exposure to gadolinium-containing contrast agents--St. Louis, Missouri, 2002-2006.: An article from: Morbidity and Mortality Weekly Report by S. Cheng (Author), L. Abramova (Author), G. Saab (Author), G. Turabelidze (Author), P. Patel (Author), M. Arduino (Author), T. Hess (Author), A. Kallen (Author), M. Jhung (Author) This digital document is an article from Morbidity and Mortality Weekly Report, published by Thomson Gale on February 23, 2007. The length of the article is 3210 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Nephrogenic fibrosing dermopathy associated with exposure to gadolinium-containing contrast agents--St. Louis, Missouri, 2002-2006. Author: S. Cheng Publication: Morbidity and Mortality Weekly Report (Newsletter) Date: February 23, 2007 Publisher: Thomson Gale Volume: 56 Issue: 7 Page: 137(5) Distributed by Thomson... |
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