 |
|
Fine-tuning treatments for depression
October 19, 2009CHICAGO -- New research clarifies how neurotransmitters like norepinephrine, serotonin, and dopamine, are regulated - a finding that may help fine-tune therapies for depression.
Current drugs for depression target the regulatory process for neurotransmitters, and while effective in some cases, do not appear to work in other cases.
Recent findings suggest that synucleins, a family of small proteins in the brain, are key players in the management of neurotransmitters -- specifically, alpha- and gamma-synuclein. Additionally, researchers have found elevated levels of gamma-synuclein in the brains of both depressed animals and humans.
In a study presented at the 39th annual meeting of the Society for Neuroscience, Georgetown University Medical Center researchers observed increased depressive-like behavior in mice where gamma-synuclein acts alone to regulate neurotransmitters, confirming earlier studies by this group.
"These findings show the importance of, and clarify a functional role for, gamma synuclein in depression and may provide new therapeutic targets in treatment of this disease," says Adam Oaks, a student researcher in the Laboratory of Molecular Neurochemistry at GUMC. "Understanding how current therapies work with the synucleins is important because the drugs don't work for all patients, and some are associated with side effects including an increased risk of suicide."
Georgetown University Medical Center
In a study presented at the 39th annual meeting of the Society for Neuroscience, Georgetown University Medical Center researchers observed increased depressive-like behavior in mice where gamma-synuclein acts alone to regulate neurotransmitters, confirming earlier studies by this group.
"These findings show the importance of, and clarify a functional role for, gamma synuclein in depression and may provide new therapeutic targets in treatment of this disease," says Adam Oaks, a student researcher in the Laboratory of Molecular Neurochemistry at GUMC. "Understanding how current therapies work with the synucleins is important because the drugs don't work for all patients, and some are associated with side effects including an increased risk of suicide."
Georgetown University Medical Center
Neurotransmitters Current Events and Neurotransmitters News RSSChanges in brain chemicals mark shifts in infant learning
When do you first leave the nest? Early in development infants of many species experience important transitions-such as learning when to leave the protective presence of their mother to start exploring the wider world.
Why antidepressants don't work for so many
More than half the people who take antidepressants for depression never get relief.
Antidepressants: benefit of SNRI is proven
The Institute for Quality and Efficiency in Health Care (IQWiG) was commissioned by the Federal Joint Committee (G-BA) to investigate whether patients with depression benefit from taking drugs belonging to the selective serotonin and norepinephrine reuptake inhibitor (SNRI) drug class.
Excessive exercise can be addicting, new study says
Although exercise is good for your health, extreme exercise may be physically addicting. Rats given a drug that produces withdrawal in heroin addicts went into withdrawal after running excessively in exercise wheels, according to new research. Rats that ran the hardest had the most severe withdrawal symptoms.
Live recordings of cell communication
A new advanced method for nano-scale imaging of vesicle-fusion - vesicles are biological nano-sized containers - could add to our understanding of diseases of the nervous system and viral infections.
UCLA scientists present first genetic evidence for why placebos work
Placebos are a sham - usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.
One step closer to an artificial nerve cell
Scientists at the Swedish medical university Karolinska Institutet and Linköping University are well on the way to creating the first artificial nerve cell that can communicate specifically with nerve cells in the body using neurotransmitters.
ADHD genes found, known to play roles in neurodevelopment
Pediatric researchers have identified hundreds of gene variations that occur more frequently in children with attention-deficit hyperactivity disorder (ADHD) than in children without ADHD.
Mouse model of Parkinson's reproduces nonmotor symptoms
The classic symptoms of Parkinson's disease involve tremor, stiffness and slow movements. Over the last decade, neurologists have been paying greater attention to non-motor symptoms, such as digestive and sleep problems, loss of sense of smell and depression.
UBC researchers develop new method to study gambling addictions
UBC researchers have created the world's first animal laboratory experiment to successfully model human gambling.
More Neurotransmitters Current Events and Neurotransmitters News Articles
 |
Neurotransmitters and Neuromodulators: Handbook of Receptors and Biological Effects by Oliver von Bohlen und Halbach (Author), Rolf Dermietzel (Author) A complete update of the highly acclaimed handbook with data on all neurotransmitters and the majority of neuromodulators. The coverage is now even more comprehensive, with 15% more entries on neuropeptides, "classic" neurotransmitters and related substances in a clear, alphabetical format. The methodological section has been expanded by 50% and now includes color figures, plus new chapters on genomics, proteomics, databases, microarrays, MALDI-TOF, neutrophins, FGF, endocannabinoids and neuroimaging. The text provides clearly structured information on the biosynthesis and degradation, localization, receptors, signal transduction pathways, and biological effects in the central nervous system, with all substances uniformly treated for an easy comparison of data. Furthermore, introductory... |
 |
Balance Your Brain, Balance Your Life: 28 Days to Feeling Better Than You Ever Have by Jay Lombard (Author), Christian Renna (Author), Armin A. Brott (Author) Acclaim for Balance Your Brain Balance Your Life "Balance Your Brain, Balance Your Life breaks new ground in psychology and medicine and promises to change the way we think about health and disease." "This innovative and interesting book will help you feel great and live life to its fullest." "Dr. Lombard is at the forefront of the emerging field of neuropsychiatry and this book explains it all in a way that is practical and easily understood." "Anyone seeking greater balance in life can find much useful practical information in this book." |
 |
Super Balanced Neurotransmitter Complex® 750mg 90 Caps by Pain & Stress Center Products If you remove all the water and fat from the body, 75% of what remains are amino acids. Amino Acids are the building blocks of all proteins. You cannot store essential amino acids so they must be replenished daily by supplementation. An unbalanced diet, anxiety and stress plus other factors can contribute to disturbances in amino acid metabolism. Super BNC feeds your brain the needed nutrients to enhance maximum utilization. Stress precipitates a progressive decline in overall cognitive functions. Super BNC contains 13 amino acids that supply your brain with inhibitory neurotransmitters, the chemical language of the brain. Super BNC is designed to address specific deficiencies in your brain caused by stress/anxiety, metabolic disorders, trauma, medications, and aging. You require a... |
 |
The Biochemical Basis of Neuropharmacology (Cooper, The Biochemical Basis of Neuropharmacology) by Jack R. Cooper (Author), Floyd E. Bloom (Author), Robert H. Roth (Author) Aside from the usual updating of material, the major change in this edition is an extensive rewriting of the chapter on memory and learning to emphasize that genes that are involved in behavior are not immutable but their expression can be modified by transcription factors. Thus, with respect to learning, that old question about which is more important, nature or nuture, genetics or environment, should be answered with the question, which leg is more important for walking, the left leg or the right? |
 |
Source Naturals Acetyl L-Carnitine, 250 mg, Tablets, 120 tablets by Source Naturals Dietary supplement. Acetyl L-Carnitine is an amino acid-like compound that is related to choline and may assist in the conversion of choline into acetylcholine. Acetylcholine, one of the body's key neurotransmitters, chemically transmits messages from one nerve cell to another (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease). Suitable for vegetarians. Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, starch, salt, preservatives or artificial color, flavor, or fragrance. |
|
The Neurotransmitters by The Neurotransmitters | |
 |
Neurotransmitter Prishilla (Primary Contributor) |
 |
Source Naturals Taurine, 500 mg, Tablets, 120 tablets (Pack of 3) by Source Naturals Dietary supplement. Calming neurotransmitter. Taurine is a crystalline, free-form amino acid. It is a soothing, inhibitory neurotransmitter and plays a major role in stabilizing the heart-beat and electrical activity of the nerves. Taurine is also necessa |
 |
Anxiety Control 24® Hour by Pain & Stress Center Products Anxiety Control 24 is a unique patented amino acid support formula. Everyone becomes stressed, apprehensive, worried, or uneasy from time to time. Anxiety is the body's normal reaction to stressful situations. Anxiety Control 24 is a 24 hour a day formula. Anxiety Control 24 provides enriching levels of amino acids, herbs, minerals and essential cofactors to help the brain's natural inhibitory system cope with the normal stress and anxiety in everyday life. Anxiety Control 24 was researched and formulated by Dr. Billie J. Sahley and was recently awarded an U.S. patent for its unique combination of ingredients. Anxiety Control 24 contains the major inhibitory neurotransmitters in the brain. Neurotransmitters are the chemical language of the brain. B6, included in this formula, is the... |
 |
The War of the Soups and the Sparks: The Discovery of Neurotransmitters and the Dispute Over How Nerves Communicate by Elliot S. Valenstein (Author) The War of the Soups and the Sparks tells the engaging story of the dispute between the pharmacologists who uncovered the first evidence that nerves communicate by releasing chemicals and the neurophysiologists who dismissed the proof and remained committed to electrical explanations. At the center of the story are the neuroscientist Otto Loewi and the pharmacologist Henry Dale, who received Nobel Prizes for their work, and the physiologist Walter Cannon, who would have shared the prize if he had not been persuaded to adopt a controversial theory. Expertly researched and recounted, The War of the Soups and the Sparks is the absorbing and enlightening tale of an immensely consequential scientific discovery. |
| © 2009 BrightSurf.com |