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Taking aim at mysterious DNA structures in the battle against cancer
November 05, 2009Designers of anti-cancer drugs are aiming their arrows at mysterious chunks of the genetic material DNA that may play a key role in preventing the growth and spread of cancer cells, according to an article in the current issue of Chemical & Engineering News, ACS' weekly newsmagazine.
C&EN Deputy Assistant Managing Editor Stu Borman notes that the DNA structures, which scientists term "quadruplexes" because they have four-sided structures, are a genre of folded DNA that may help control whether genes are switched on or off. Quadruplexes sometimes form near genes that foster the growth of cancer cells. Some scientists thus regard them as promising targets for developing new anti-cancer drugs.
Drugs that interact with quadruplexes could help kill cancer cells without harming healthy cells. In addition, they may side-step the serious problem of drug resistance, in which some drugs gradually lose their effectiveness against cancer. The article describes research on quadruplex-targeted drugs and explores the mysteries about how quadruplexes form, disappear, and work.
American Chemical Society
American Chemical Society
Cancer Cells Current Events and Cancer Cells News RSSCommon pain relief medication may encourage cancer growth
Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells.
Cancers' Sweet Tooth May Be Weakness
The pedal-to-the-metal signals driving the growth of several types of cancer cells lead to a common switch governing the use of glucose, researchers at Winship Cancer Institute of Emory University have discovered.
UCLA researchers create 'fly paper' to capture circulating cancer cells
Just as fly paper captures insects, an innovative new device with nano-sized features developed by researchers at UCLA is able to grab cancer cells in the blood that have broken off from a tumor.
Paradoxical protein might prevent cancer
One difficulty with fighting cancer cells is that they are similar in many respects to the body's stem cells. By focusing on the differences, researchers at Karolinska Institutet have found a new way of tackling colon cancer. The study is presented in the prestigious journal Cell.
Cornell researchers identify a weak link in cancer cell armor
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves.
Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor
This research validates the potential for Stapled Peptides to modulate key intracellular biological targets, such as transcription factors, that have not been addressable with current small molecule or biologic drug modalities.
Researchers 'notch' a victory toward new kind of cancer drug
Scientists have devised an innovative way to disarm a key protein considered to be "undruggable," meaning that all previous efforts to develop a drug against it have failed.
Barrow study identifies new way to biopsy brain tumors in real time
A new miniature, hand-held microscope may allow more precise removal of brain tumors and an easier recognition of tumor locations during surgery.
Coffee break: Compound brewing new research in colon, breast cancer
A compound in coffee has been found to be estrogenic in studies by Texas AgriLife Research scientists.
Newly Discovered Fat Molecule: An Undersea Killer with an Upside
A chemical culprit responsible for the rapid, mysterious death of phytoplankton in the North Atlantic Ocean has been found by collaborating scientists at Rutgers University and the Woods Hole Oceanographic Institution (WHOI). This same chemical may hold unexpected promise in cancer research.
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One Renegade Cell: The Quest For The Origin Of Cancer (Science Masters) by Robert A. Weinberg (Author) For everyone whose life has been touched by cancer, One Renegade Cell tells the story of the search for the ultimate causes of this dreaded disease. "One Renegade Cell…offers a breathtaking picture, both wonderful and frightening, of the fantastic intricacy of aberrant cellular functioning." -New York Times "Part primer, part history and part meditation. [One Renegade Cell] succeeds on all counts." -Wall Street Journal One of the leading cancer researchers in the world, Robert A. Weinberg is perfectly suited to describe the search for cancer's origins from the early days of this century to the present. Presuming little knowledge of biology, he tells how a cancer-causing virus was first discovered in 1909, how the correlation was made between chemical ... |
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Destroying Cancer Cells Using Your Subconscious Mind a Guided Imagery and Subliminal program Starring: Steve Murray Directed By: Steve Murray The DVD has two separate "Destroying Cancer Cells" self-help programs: A Guided Imagery and a Subliminal program. Both have easy-to-follow directions and can be used before, during, and after cancer treatments. Guided Imagery is the language of the mind. It is a way of communicating with parts of the body that cannot speak in words. You will learn this language in the DVD. Research has shown Guided Imagery is a powerful self-help tool. The Guided Imagery program starts with a relaxation technique, then guides you through ten imagery segments. Subliminal Messages have been used for years by advertisers to reprogram and change one s subconscious mind about their products. With this DVD, you will use Subliminal Message s for your benefit. During the subliminal program all you have to do is... |
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Cancer Research / Testing Cells Directed By: Rex Barnett |
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Cancer and the Immune System : Cell-to-Cell Communication, An Introduction (31 minute colour VHS video) (NTSC video) by Spektrum Videothek Produced in Germany. In English. "This documentary focuses on... findings in immunilogical research." | |
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Cell Phone Strap - Breast Cancer Support Pink Ribbon - 8" by Trutex |
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Dissolving & Destroying Cancer Cells "A Guided Imagery Program" [VHS] Also With: steve murray (Primary Contributor) Steve Murray the author of "Cancer Guided Imagery Program for Radiation, Chemotherapy, Surgery and Recovery" now has a series of DVDs and Videos that will help you: Tap into the Healing Power of the Body and Mind Connection This program when used in conjunction with your prescribed medical treatment shows you how to do just that. With easy to understand explanations and directions, you will be able to start a Cancer Guided Imagery Program right away. Guided Imagery is the language of the mind. It is a way of communicating with parts of ourselves that cannot speak in words. You will use this language in the program. Program Includes: -Directions on how to do program-Guided relaxation and ten Cancer Guided Imagery segments-Soothing music, calm peaceful images- Verbal and... |
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Fight Against Kidney (Renal Cell) Cancer Sweatshirt XX-Large White by Shop Zeus |
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Antioxidant + Resveratrol , (60 Capltes/bottle) This product provides nutritional support to defend against the effects of free radicals. Resveratrol is a type of polyphenol called a phytoalexin. Resvertraol works by binding to a class of proteins called sirtuins, which regulate the enzymes that can stimulate cancer-cell growth and suppress immune response. Resveratrol may also have powerful and diverse effects on the heart and blood vessels. by Vitamore Free-radicals (also called oxidants) are highly unstable molecules that can damage cell membranes. This may start a process that leads to several chronic diseases and may be involved with many aspects of aging. Free radicals are produced in the body during normal cell metabolism, and may also be caused by other environmental and lifestyle factors such as stress, smoking, polution, etc. This product provides nutritional support to defend against the effects of free radicals using the antioxidant vitamins of C and E and the trace elements of Zinc and Selenium. The key ingredient is the flavonoid-rich Resveratrol. Resveratrol is a type of polyphenol called a phytoalexin. Resvertraol works by binding to a class of proteins called sirtuins, which regulate the enzymes that can stimulate... |
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