 |
|
Protein transport in mitochondria revealed
March 31, 2005The TIM23 complex, which regulates the transport of protein to the mitochondria in a cell, is much more complicated than was previously believed. This is shown by Uppsala University researcher Maria Lind in an article in the leading journal Cell.
Together with Agnieszka Chacinska from the University of Freiburg in Germany, Maria Lind from Uppsala University is lead author of the article in Cell.
"The complex opens only a single channel when the protein comes, in order not to disturb the negative or positive charge on the respective sides of the complex," explains Maria Lind.
"It is essential that the voltage created by the difference in the charges be maintained when the mitochondria are to produce energy."
The TIM23 complex can also change shape depending on where the protein is ultimately to be transported. In this way the same complex can transport proteins to different final destinations.
Maria Lind and Agnieszka Chacinska have also identified a new protein, Tim21, which participates in protein transport.
Defects in mitochondria give rise to some one hundred disorders, including Huntington's disease, Mohr-Tranebjaerg syndrome, Parkinson's disease, and Alzheimer's disease.
"We need more knowledge about mitochondria if we are to be able to understand these diseases," avers Maria Lind.
The study was carried out on yeast, which researchers often use as a model organism because it is one of the simplest organisms with mitochondria.
"But mitochondria function in the same way in all organisms, and there are many things in yeast cells that are similar to human cells," says Maria Lind.
VetenskapsrÄdet (The Swedish Research Council)
Science Research Departments
Earth Science
Alternative Energy | Anthropology and Archaeology | Earthquakes and Volcanoes | Environment and Nature News | Global Warming | High-Energy and Particle Physics | Ozone Hole | Scientists Slow Light | Tsunami
Space Science
Astronomy and Space News | Black Holes | Chandra X-Ray Observatory | Extrasolar Planets | Hubble Telescope | International Space Station | Jupiter Galileo Mission | Jupiter Cassini Mission Flyby | Mars Exploration | Mars Odyssey 2001 | Mars Global Surveyor | Mars Polar Lander | Mars Climate Orbiter | Mars Pathfinder | Meteors and Asteroids | Mir Space Station | NEAR Asteroid Probe Mission | Pluto Planet Debate | Search for Extraterrestrial Life | Space Shuttle Program | Space Shuttle Mission: STS-102 | Space Weather
Life Science
Animal News | Biotechnology and Genetics | Brain Research | Human Cloning | Dinosaur and Fossil Discoveries | Endangered Species | Gene Therapy | Genetically Modified Food | Stem Cell Research | Whales and Whaling
 |
Scientific Explorer's Mind Blowing Science Kit for Young Scientists by Scientific Explorer Mind blowing experiments to delight and educate young scientists! Erupt a color changing volcano. Mix up magic ooze with a mind of its own. Play with sand that never gets wet. Mix safe chemicals and watch colors change before your eyes. You'll amaze yourself and your friends as you explore the science behind these truly remarkable reactions. |
 |
The Everything Kids' Science Experiments Book: Boil Ice, Float Water, Measure Gravity-Challenge the World Around You! (Everything Kids Series) by Tom Robinson (Author) Science has never been so easy - or so much fun! With The Everything Kids' Science Experiments Book, all you need to do is gather a few household items and you can recreate dozens of mind-blowing, kid-tested science experiments. High school science teach Tom Robinson shows you how to expand your scientific horizons - from biology to chemistry to physics to outer space. You'll discover answers to questions like: Get ready to enter the laboratory and learn how to conduct cool experiments, understand scientific terms... |
 |
Scientific Explorer's Disgusting Science - A Kit for Studying the Science of Revolting Things by Scientific Explorer Grow your own friendly germs and fuzzy molds. Mix up a batch of coagulating fake blood. Even make a stinky intestine. learn the science behind unmentionable bodily functions while doing some truly NASTY Experiments. Ages 8+ |
 |
The Science Book: Everything You Need to Know About the World and How It Works (National Geographic) by National Geographic (Author), Marshall Brain (Foreword) A delight for the casual reader, yet so complete and wide-ranging that science buffs and students will welcome it, The Science Book encapsulates centuries of scientific thought in one richly illustrated volume. Natural phenomena, revolutionary inventions, and the most up-to-date investigations are explained in detailed text, and 2,000 vivid illustrationsÂincluding 3-D graphics and pictogramsÂmake the information even more accessible and amazing to discover. The Science Book offers both a general overview of topics for the browsing reader and more specific information for those seeking deeper insight into a particular subject. Six major sections, ranging from the universe and planet Earth to biology, chemistry, physics, and mathematics, encompass everything from microscopic life... |
 |
Scientific Explorer's The Magic Science Wizard's Kit by Scientific Explorer Cast real smoke from your fingertips, make a wizard wand, and whip up color-changing potions in your test tube laboratory. Also included are laminated cards with wizard facts, an instruction booklet with 11 activities, lab equipment, and mysterious wizard powders that will mix together to mystify you! |
 |
Magic School Bus Journey into the Human Body Science Kit by Young Scientist Club The Magic School Bus and Ms. Frizzle take Young Scientists on a wild ride into the human body with these breathtaking experiments. Young Scientists bend bones, make joints, map taste buds, expand lungs, build a stethoscope, measure lung capacities and heart rates, perform the iodine starch test, spin glitter, simulate synovial fluid, create a human body poster, and much, much more! This exciting kit includes a life-size poster with eight sheets of body part stickers. So put on your seat belts, students, and get ready to discover The Human Body! |
 |
The Complete Book of Science, Grades 5-6 by School Specialty Publishing (Author) The Complete Book of Science for grades 5 to 6 teaches children important science skills!
Children complete a variety of exercises that help them develop a number of skills in this 352 page workbook. Including a complete answer key this workbook features a user-friendly format perfect for browsing, research, and review.
Over 4 million in print! The best-selling Complete Book series offers a full complement of instruction, activities, and information about a single topic or subject area. Containing over 30 titles and encompassing preschool to grade 8 this series helps children succeed in every subject area! ... |
 |
Scientific Explorer's Tasty Science Chemistry in the Kitchen Kit by Scientific Explorer Who knew science could taste so good? With this kit, youâll whip up cupcakes, cookies, candy, and moreâall in the name of science! Learn what makes cakes rise, candy crystallize, and more real chemistry happen in the kitchen. Tasty Science is packed with ingredients, recipes, activity cards, a test tube laboratory, and lots more to explore the science of taste. |
 |
What Is the World Made Of? All About Solids, Liquids, and Gases (Let's-Read-and-Find-Out Science, Stage 2) by Kathleen Weidner Zoehfeld (Author), Paul Meisel (Author) Did you ever walk through a wall? Drink a glass of blocks? Have you ever played with a lemonade doll, or put on milk for socks? This latest addition to the Let's-Read-and-Find-Out Science series introduces the youngest readers to an important science concept: the differences between solids, liquids, and gases. Any child who wants to know why he can't walk through a wall will enjoy Kathleen Zoehfeld's simple text and Paul Meisel's playful illustrations. |
 |
Scientific Explorer's Spa Science Chemistry Kit by Scientific Explorer Whip your bath into a frothy fizzing sea of color and fragrance. Make colorful, fragrant bath gels, bath fizzers, spa lotion, bath balm, a face mask, and shampoo. Mix colors and fragrances to creat your own product line with secret and exclusive mixtures. Explore the science of gels, fragrance and fizzers. |
| © 2009 BrightSurf.com |