Science Current Events | Science News | Brightsurf.com
 

New clinical practice guidelines on alcoholic liver disease published

April 19, 2012
EASL today announced the publication of a new clinical practice guideline (CPG) in the area of Alcoholic Liver Disease (ALD), bringing the number of CPGs published to date to eight.

ALD, a result of regular and heavy drinking, is the leading cause of liver disease in eastern and western Europe.(1) Europe has the highest alcohol consumption in the world, at 12.18 litres of pure alcohol per person per year.(1) Despite this there has been limited research investment in this area and the development of clinical practice guidelines is therefore both timely and necessary.

The EASL Clinical Practice Guidelines on Alcoholic Liver Disease, build on the issues raised at the Monothematic Conference on Alcoholic Liver Disease, held in Athens in 2010 and have been developed with three main aims. These are to:

Provide physicians with clinical recommendations
Emphasise the fact that alcohol can cause several liver diseases (steatosis, steatohepatitis, cirrhosis), all of which may coexist in the same patient
Identify areas of interest for future research, including clinical trials

The guidelines cover the burden of ALD, management of alcohol abuse and dependence, pathogenesis, risk factors for disease progression, diagnosis, alcoholic hepatitis, alcoholic cirrhosis and liver transplantation. The Clinical Practice Guidelines will be published in August in EASL's Journal of Hepatology.

In addition, EASL has also published a revised CPG on the Management of Chronic Hepatitis B. This update incorporates changes to a number of areas including: new indications for liver biopsy and the treatment of HBeAg-negative patients; the recommendation for less frequent HBV DNA testing under ETV or TDF; and the provision of more detailed recommendations for specific sub-groups, particularly HBV and pregnancy and HBV and immunosuppression.

CPGs define the use of diagnostic, therapeutic and preventive modalities, including non-invasive and invasive procedures, in the management of patients with various liver diseases. They are intended to assist physicians and other healthcare providers, as well as patients and interested individuals, in the clinical decision making process by describing a range of generally accepted approaches for the diagnosis, treatment and prevention of specific liver diseases.

In addition, a CPG is in development for the Management of Acute Liver Failure. More information on EASL's CPGs can be found on the EASL website at http://www.easl.eu/_clinical-practice-guideline.

References

1. Handbook for action to reduces alcohol-related harm. World Health Organization Regional Office for Europe. 2009. http://www.euro.who.int/__data/assets/pdf_file/0012/43320/E92820.pdf. Accessed 04.04.12.

European Association for the Study of the Liver


Related Liver Disease Current Events and Liver Disease News Articles


Surveys miss majority of poisonings, underestimate cost by billions
Health surveys may underestimate the number of poisonings in the United States by 60 percent to 90 percent, according to a report in the journal Clinical Toxicology by University of Illinois at Chicago researchers.

High fidelity: SLU researcher finds keys to genome integrity
Maintaining the stability and the correct sequence of our genetic information is vital to the accurate transmission of our genetic code.

Standard nursing assessments improve ability to predict survival in cirrhosis patients
Patients hospitalized with advanced cirrhosis, a chronic and degenerative disease of the liver, are at increased risk of death.

Study tallies huge cost of hepatitis C drugs for RI prisons
A new study finds that effective new hepatitis C drugs are so expensive the state of Rhode Island would have to spend almost twice its entire prison health budget to treat all its chronically infected inmates.

New study indicates that exercise improves non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of frequency or intensity, benefits obese and overweight adults with NAFLD.

Protein may improve liver regeneration
Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal.

Newly enlisted T-cell 'policemen' can slow down run-away immune system, SLU scientist says
In research published in the March issue of Immunity, Saint Louis University scientists led by Daniel Hawiger, M.D., Ph.D., assistant professor of molecular microbiology and immunology, have discovered that potentially aggressive T-cells that might lead to auto-immune disease can instead be enlisted to help "police" over-active immune responses, via the molecule CD5.

BMC study: New Hepatitis C treatments cost-effective, but only for selected patients
A study led by Boston Medical Center (BMC) researchers demonstrates that while new therapies to treat Hepatitis C Virus (HCV) are highly effective, they are cost-effective and provide the greatest value in specific groups of HCV-infected patients.

Live donor liver transplantation found safe and effective for acute liver failure
When patients develop acute liver failure, severe complications arise rapidly after the first signs of liver disease, and patients' health can deteriorate rapidly.

Scientists grow 'mini-lungs' to aid the study of cystic fibrosis
Scientists at the University of Cambridge have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease.
More Liver Disease Current Events and Liver Disease News Articles

The First Year: Cirrhosis: An Essential Guide for the Newly Diagnosed

The First Year: Cirrhosis: An Essential Guide for the Newly Diagnosed
by James L. Dickerson (Author), Fredric Regenstein (Foreword)


More than 25 million Americans and 92 million worldwide suffer from liver disease and cirrhosis, a degenerative and potentially fatal condition in which liver cells are damaged and then replaced by scar tissue, impeding liver function. The disease is most commonly caused by excessive alcohol consumption, hepatitis, or complications from prescription drugs. Immediately after his diagnosis, James Dickerson set out to educate himself on all of his options — and found there is hope for recovery. Now, he offers The First Year: Cirrhosis, the first guide for patients and their families to understanding and managing this chronic condition. In clear, accessible language, the book walks readers step-by-step through everything they need to do each day of the first week after a cirrhosis...

Dr. Melissa Palmer's Guide To Hepatitis and Liver Disease

Dr. Melissa Palmer's Guide To Hepatitis and Liver Disease
by Melissa Palmer (Author)


In the United States alone, more than four million people are infected with the hepatitis C virus, and chronic liver disease is the twelfth leading cause of death.

In this revised and updated edition of her groundbreaking 2000 book, renowned hepatologist Dr. Melissa Palmer discusses all facets of liver disease, from symptoms and tests to treatment options and lifestyle changes. In addition, this comprehensive handbook reveals cutting-edge research on the dangers of hepatitis C, one of the world's fasting-growing microbial threats.

Fatty Liver Cure: The Natural Fatty Liver Cure Ultimate Guide! - Proven Diet Plan Strategies to Reverse And Prevent Fattly Liver Disease Through Nutrition, ... Natural Cures, Juicing, Smoothies Recipes)

Fatty Liver Cure: The Natural Fatty Liver Cure Ultimate Guide! - Proven Diet Plan Strategies to Reverse And Prevent Fattly Liver Disease Through Nutrition, ... Natural Cures, Juicing, Smoothies Recipes)


FATTY LIVER CURE ULTIMATE GUIDE!This "Fatty Liver Cure" book contains proven steps and strategies on how to prevent and manage fatty liver, a potentially fatal health condition, using natural techniques.Today only, get this Amazing Amazon book for this incredibly discounted price! Read on your PC, Mac, Smart Phone, Tablet or Kindle Device.While most people (including some medical professionals) are pessimistic about the prospects of having to deal with a fatty liver, it’s a comforting thought to know that it doesn’t have to be a dead-end disease. Thru the information I will share in this book, you’ll find out about the all-natural preventive and curative techniques you can use to properly manage fatty liver.There are all kinds of specific information you can learn in this book....

Fatty Liver You Can Reverse It

Fatty Liver You Can Reverse It
by Sandra Cabot M.D. (Author), Thomas Eanelli MD (Author)


This handbook examines the most common type of liver disease-fatty liver-and offers a comprehensive plan to reverse the condition and restore health. In addition to providing an extensive overview of the disease, its causes, and tools for diagnosing and determining the level of severity, the reference features a step-by-step path for healing. Among the information provided for those seeking to eradicate this disease, and reduce the incidence of blood clots, cancer, diabetes, heart attacks, and weight gain, is a description of basic dietary principles and natural therapies to heal damaged and fatty liver cells. An extensive personal essay-"Confessions of a Fat Man" by Thomas Fanelli MD-reveals a true-life example of one person's emotional battle with food addiction and fatty liver disease....

The Fatty Liver Cure: The Ultimate Principles To Reverse And Cure Fatty Liver  And Lose Weight NOW ! (Volume 1)

The Fatty Liver Cure: The Ultimate Principles To Reverse And Cure Fatty Liver And Lose Weight NOW ! (Volume 1)
by R. Huntington (Author)


*****LIMITED TIME OFFER***** The Fatty Liver Cure, The Ultimate Principles To Reverse A Fatty Liver And Lose Weight NOW ! *****3rd EDITION***** The Fatty Liver Cure provides proven and clear steps to cure your fatty liver for once and for all. There is absolute no need to go on a full fatty liver diet. Of all the organs, it is the liver which directly controls the development and performance of all the body cells. Due to its unique design, your liver may look as if it works normally through blood values that are balanced even if it has lost 60% of its initial effectiveness. This can deceive you and your doctor. Most of the health diseases originate from the liver. In this book you're about to discover proven strategies on how to cure and prevent a fatty liver. This one-of-a-kind...

Healing Hepatitis and Liver Disease Naturally: Detoxification. Liver gall bladder flush & Cleanse. Cure Hepatitis C and Hepatitis B. Lower blood cholesterol and stop cirrhosis

Healing Hepatitis and Liver Disease Naturally: Detoxification. Liver gall bladder flush & Cleanse. Cure Hepatitis C and Hepatitis B. Lower blood cholesterol and stop cirrhosis
by Peter Oyakhire (Author)


LIVE YOUR LIFE EXPECTANCY WITH CHRONIC LIVER DISEASE.

Studies show that all wellness traditions except western medicine offer detoxification and toxic waste management as a means of natural healing. Using the principles of natural healing and detoxification, Dr. Alexis Carrel, a Nobel Prize winner kept chicken heart alive for 38 years. He believed that cells could live indefinitely and that the secret of life is to feed nutrients to cells and to saturate the cells with Oxygen. If you can't get nutrients into the cells and you don't remove the toxins, the cells will be poisoned by their own waste products. He had found the secret to ageless body and timeless health.

Often overlooked is the pain associated with orthodox management of infective and degenerative liver diseases...

Liver Disease 101: What You Need to Know about Fatty Liver, Liver Detox and Liver Diet

Liver Disease 101: What You Need to Know about Fatty Liver, Liver Detox and Liver Diet


What do you really know about your Liver? If you really want to understand and do something about it, continue reading!

Today only, get this Amazon bestseller for just $0.99. Regularly priced at $4.99. Read on your PC, Mac, smart phone, tablet or Kindle device.


This book will help you better understand liver-related health issues and see how you can deal with it.

It has been written as a general overview outlining the main things you need to know about this subject. It's a short read and a great start for people who know little about the subject.

There are more than 100 different types of liver disease, which together affect millions of people around the world.

The liver is the second largest organ in the body. It...

Healing Fatty Liver Disease: A Complete Health and Diet Guide, Including 100 Recipes

Healing Fatty Liver Disease: A Complete Health and Diet Guide, Including 100 Recipes
by Dr. Maitreyi Raman (Author), Angela Sirounis (Author), Jennifer Shrubsole (Author)


Nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease in North America. Some people with excess fat in the liver simply have what's called a fatty liver. Although this is not normal, it's not serious if it doesn't lead to inflammation or damage. However, once there's a buildup of simple fat, the liver becomes vulnerable to injury which may result in inflammation and scarring of the liver. Others have what's called Nonalcoholic Steatohepatisis (NASH). Although it is similar to alcoholic liver disease, people with this type of fatty liver disease drink little or no alcohol. NASH can lead to permanent liver damage, as the liver may enlarge and, over time, liver cells may be replaced by scar tissue. This is called cirrhosis. Unfortunately...

Sleisenger and Fordtran's Gastrointestinal and Liver Disease- 2 Volume Set: Pathophysiology, Diagnosis, Management, 10e (Gastrointestinal & Liver Disease (Sleisinger/Fordtran))

Sleisenger and Fordtran's Gastrointestinal and Liver Disease- 2 Volume Set: Pathophysiology, Diagnosis, Management, 10e (Gastrointestinal & Liver Disease (Sleisinger/Fordtran))
by Mark Feldman MD (Author), Lawrence S. Friedman MD (Author), Lawrence J. Brandt MD (Author)


Now in its 10th edition, Sleisenger and Fordtran's Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments-with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos.Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence. Zero in on the key information you need to know with a...

Schiff's Diseases of the Liver

Schiff's Diseases of the Liver
by Eugene R. Schiff (Author), Willis C. Maddrey (Author), Michael F. Sorrell (Author)


For over 50 years covering 10 previous editions, Schiff's Diseases of the Liver has provided hepatologists with an outstanding evidence-based clinical reference work covering all aspects of liver disease, and is without doubt one of the world’s leading hepatology textbooks.  Now fully revised and updated, it will serve as your first-stop reference for today’s demanding clinical situations. With a strong clinical focus, Schiff’s Diseases of the Liver covers anatomy, pathology, testing, imaging, and effects of liver disease on other organs, before moving on to sections that address specific diseases and clinical syndromes.  Its enormous appeal has been due to the clarity of text, combined with the sheer thoroughness of its breadth of content. Key features include: An attractive...

© 2015 BrightSurf.com