Science Current Events | Science News | Brightsurf.com
 

Vitamin D: A double-edged sword in the fight against osteoporosis

April 24, 2012
Vitamin D is renowned for its role in creating strong bones and is a key regulator of serum calcium levels. Calcium is primarily obtained through diet and absorbed through the intestine and into the blood stream. In addition to building bone, calcium is required for a variety of important physiological processes. Vitamin D, which is detected by receptors in bone and intestinal cells, regulates the level of calcium in the blood stream and determines how much should be stored in the skeleton. Several recent clinical trials have examined the effects of vitamin D supplements on the prevention of bone fractures in the elderly; however, the results of these trials have not offered a consensus on the efficacy of these supplements.

In this month's issue of JCI, Dr. Geert Carmeliet and colleagues at the University of Leuven in Leuven, Belgium, investigated how vitamin D affects the skeleton when serum calcium levels are depleted. Using mice that lack the intestinal vitamin D receptor, the researchers showed that the mice still had normal serum calcium levels even when given a low-calcium diet. Additional experiments demonstrated that vitamin D stimulated bone cells to produce factors that removed calcium from bone in a process known as bone resorption in order to maintain normal serum calcium levels. Thus, while vitamin D is important for maintaining serum calcium levels, it can also promote bone density loss.

In an accompanying article, Dr. Cathleen Colón-Emeric and Dr. Kenneth Lyles of Duke University Medical Center in Durham, North Carolina, discuss the clinical implications of this investigation as well as how these findings may explain clinical trial results where vitamin D supplements failed to prevent fractures in elderly patients and, in some cases, were correlated with increased fracture rates.

Journal of Clinical Investigation


Related Osteoporosis Current Events and Osteoporosis News Articles


Proper Stem Cell Function Requires Hydrogen Sulfide
Stem cells in bone marrow need to produce hydrogen sulfide in order to properly multiply and form bone tissue, according to a new study from the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry.

Osteoporosis risk heightened among sleep apnea patients
A diagnosis of obstructive sleep apnea may raise the risk of osteoporosis, particularly among women or older individuals.

Osteoporosis drugs appear to impede cell membrane repair
A class of drugs widely used to treat osteoporosis appears to impede a cell's ability to repair a protective outer membrane that helps determine what enters and exits, researchers report.

Calcium supplementation does not increase coronary heart disease concludes new study
The results of a study presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases do not support the hypothesis that calcium supplementation, with or without vitamin D, increases coronary heart disease or all-cause mortality risk in elderly women.

Ankle fractures could be significant risk factor for subsequent fracture
A study by researchers at the University of Geneva concludes that prevalent ankle fractures should be considered as osteoporotic fractures and taken into account in fracture-risk assessment.

Swedish researchers show impact of long-term vitamin D insufficiency on fracture risk
A study presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases shows that long-term low levels of vitamin D intake are associated with higher 10-year fracture risk in elderly women.

Economic evaluation of an osteoporosis screening campaign using FRAX
In new research presented at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases today, investigators showed that an osteoporosis screening strategy using FRAX as a pre-screening tool is cost-effective if the follow up of the screening and medication adherence are optimized.

Vibration may help heal chronic wounds
Wounds may heal more quickly if exposed to low-intensity vibration, report researchers at the University of Illinois at Chicago.

A technique has been patented that opens the door to the development of new drugs against osteoporosis
Scientists from the University of Granada have developed a methodology that allows phosphate ions to be measured - in real time and none-invasively - in the interior of osteoblasts, the precursors of bone cells.

Quality of life improves with minimally invasive surgery for low back pain
Beaumont research findings published in the February online issue of Spine shows that patients who have a low back surgery called minimally invasive transforaminal lumbar interbody fusion, end up better off in many ways than patients who have more invasive surgery to alleviate debilitating pain.
More Osteoporosis Current Events and Osteoporosis News Articles

The Osteoporosis Diet: The Complete Guide To Osteoporosis Nutrition, Supplements, & Exercise To Reverse Bone Loss Without Drugs

The Osteoporosis Diet: The Complete Guide To Osteoporosis Nutrition, Supplements, & Exercise To Reverse Bone Loss Without Drugs


Are you looking for a natural approach to osteoporosis treatment?

The Osteoporosis Diet was written for those who are looking for a non-drug approach to prevent and treat osteoporosis or osteopenia.

If you're looking for a way to enjoy osteoporosis protection for life, without the need to resort to potentially toxic drugs such as: Fosamax, Boniva, Reclast, and other newer and equally toxic drugs, then The Osteoporosis Diet is the solution.

In the book you'll learn:

1. The form of calcium you will NEVER want to take. Hint: Odds are you take it right now and your doctor probably recommended it! Choose the right calcium, get strong bones. Choose the wrong calcium, lose your skeleton.

2. What it takes to make major increases in your...

The Wellness Doctor's Guide to Preventing and Reversing Osteoporosis (The Wellness Doctor Series)

The Wellness Doctor's Guide to Preventing and Reversing Osteoporosis (The Wellness Doctor Series)


Lifestyle...is the best medicine!

Osteoporosis is a completely preventable and even reversible condition! Volume 1 of the Wellness Doctor's Series will show you how!

This book is a guided road map with the dietary, exercise and supplementation specifics needed to prevent, treat and even reverse osteoporosis.

Contents include:

• Understanding Osteoporosis: what causes it, how to reverse it, what are the myths...

• What to eat for super strong bones: what foods should be eaten and what foods should be avoided, bone building teas, what to limit or avoid...

• What supplements do you need to build healthy bones: what nutrient supplements deliver on building super strong bones, what is the right dose, combination...
Your Bones: How You Can Prevent Osteoporosis and Have Strong Bones for Life - Naturally

Your Bones: How You Can Prevent Osteoporosis and Have Strong Bones for Life - Naturally
by Lara Pizzorno (Author), Jonathan V., M.D. Wright (Contributor)


Your Bones contains everything you need to know for healthy bones in one book, providing scientifically based advice which highlights natural prevention and treatment strategies. This UPDATED AND EXPANDED edition includes many new studies on the dangers of the bisphosphonate drugs and an in depth discussion of two new drugs with potential adverse effects. Also new: more information on bone-busting patent medicines, calcium supplementation options, strontium, vitamin K2, and zinc as well as a section on bone-building exercise.

The Whole-Body Approach to Osteoporosis: How to Improve Bone Strength and Reduce Your Fracture Risk (The New Harbinger Whole-Body Healing Series)

The Whole-Body Approach to Osteoporosis: How to Improve Bone Strength and Reduce Your Fracture Risk (The New Harbinger Whole-Body Healing Series)
by R. Keith McCormick (Author)


No pill will cure you of osteoporosis. While medication can sometimes help, it won't fully address the underlying causes of your osteoporosis or osteopenia. To restore bone health, you'll need a targeted program combining the best bone-building strategies from traditional and holistic medicine. The Whole-Body Approach to Osteoporosis distills these complex strategies into a whole-body plan you can begin today to dramatically improve your bone strength and overall vitality.This comprehensive guide includes information on: What to eat for stronger bones Choosing bone-building supplements and osteoporosis medications Foods and medications that may be contributing to bone loss Signs and symptoms that can help you monitor your bone health How lab tests can help you...

Osteoporosis: How To Treat Osteoporosis- How To Prevent Osteoporosis- Along With Nutrition Diet And Exercise For Osteoporosis (osteoporosis treatment, ... strengthen bone density for osteoporosis)

Osteoporosis: How To Treat Osteoporosis- How To Prevent Osteoporosis- Along With Nutrition Diet And Exercise For Osteoporosis (osteoporosis treatment, ... strengthen bone density for osteoporosis)


Get Help For Osteoporosis Now!

A must have book if you or someone else you know is suffering from Osteoporosis! Take steps now to help alleviate the damaging effects of osteoporosis or help prevent it from ever occurring! Proven strategies that really make a difference! Get relief for osteoporosis and take steps that can dramatically improve the quality of your life. Be sure and get this valuable resource.

Here Is A Preview Of What You'll Learn...
An Overview of Osteoporosis and How It Can DevelopHow To Prevent Osteoporosis All Natural Methods To Treat Osteoporosis Modern Medical Breakthroughs For Osteoporosis Exercises for OsteoporosisHerbal Remedies for OsteoporosisThe Best Supplements To Take for OsteoporosisMuch, much more!

The contents...

Yoga for Osteoporosis: The Complete Guide

Yoga for Osteoporosis: The Complete Guide
by Loren Fishman (Author), Ellen Saltonstall (Author)


A comprehensive, user-friendly medical yoga program designed for the management and prevention of osteoporosis, with more than four hundred illustrations. Osteoporosis leads to painful fractures due to loss of bone mass; yoga strengthens bones without endangering joints: it stands to reason that yoga is the perfect therapy for osteoporosis. Forty-four million Americans suffer from low bone mass, and osteoporosis is responsible for more than 1.5 million fractures annually. Drugs and surgeries can alleviate pain, but study after study has shown that exercise is the best treatment, specifically low-impact, bone-strengthening exercises—hence, yoga.

In this comprehensive and thoroughly illustrated guide, Loren Fishman and Ellen Saltonstall, who between them have seven decades of...

The Myth of Osteoporosis - Revised Edition

The Myth of Osteoporosis - Revised Edition
by Gillian Sanson (Author)


This revised edition provides important information about the latest studies and the newest drugs on the market. Gill Sanson's book is a well-researched breath of fresh air that will help women everywhere better trust the wisdom of their bodies. -- Christiane Northrup, M.D. The Myth of Osteoporosis is a research-based work that provides clear insight into the myths of osteoporosis. These myths motivate both patient and physician into a lifetime of unnecessary testing and drug therapy therapy that can in fact be life-threatening. Gillian Sanson's well-documented explanation of these myths can spare women great anxiety. She takes the fear out of aging and restores women's sense of control over their bodies. She gives women good reasons for challenging the common way that osteoporosis is...

Osteoporosis For Dummies

Osteoporosis For Dummies
by Carolyn Riester O'Connor (Author), Sharon Perkins RN (Author)


Facts and advice to help people understand and prevent osteoporosisThere are an estimated 55 million Americans over the age of 50 who have low bone mass. This easy-to-understand guide helps readers assess their risk and find a practical approach to the diagnosis, treatment, and prevention of osteoporosis. It covers bone density tests and a wide range of treatment options for osteoporosis-from hormone replacement therapy and acupuncture to calcium-rich foods, supplements, and exercise-and offers pointers on preventing broken hips and other common fractures.

Walk Tall! An Exercise Program for the Prevention & Treatment of Back Pain, Osteoporosis and the Postural Changes of Aging, 2nd Edition

Walk Tall! An Exercise Program for the Prevention & Treatment of Back Pain, Osteoporosis and the Postural Changes of Aging, 2nd Edition
by Sara Meeks (Author), PT MS GCS (Author), Triad Publishing Company (Editor)


An exercise program for the prevention & treatment of back pain, osteoporosis and the postural changes of aging.

Building Bone Vitality: A Revolutionary Diet Plan to Prevent Bone Loss and Reverse Osteoporosis--Without Dairy Foods, Calcium, Estrogen, or Drugs

Building Bone Vitality: A Revolutionary Diet Plan to Prevent Bone Loss and Reverse Osteoporosis--Without Dairy Foods, Calcium, Estrogen, or Drugs
by Amy Lanou (Author), Michael Castleman (Author)


Calcium pills don't work. Dairy products don't strengthen bones. Drugs may be dangerous. For years, doctors have been telling us to drink milk, eat dairy products, and take calcium pills to improve our bone vitality. The problem is, they’re wrong. This groundbreaking guide uses the latest clinical studies and the most upto- date medical information to help you strengthen your bones, reduce the risk of fractures, and prevent osteoporosis. You’ll learn why there’s no proof of calcium’s effectiveness, despite what doctors say, and why a low-acid diet is the only effective way to prevent bone loss. "This clear, convincing explanation of osteoporosis will change the way the world thinks about bone health. Lanou and Castleman prove beyond doubt that milk and dairy are the problem, not...

© 2014 BrightSurf.com