Rutgers Study: Vitamin E in Diet Protects Against Many CancersApril 24, 2012
Next time you need to choose between vegetable oil and margarine in that favorite recipe, think about your health and reach for the oil.
While the question of whether vitamin E prevents or promotes cancer has been widely debated in scientific journals and in the news media, scientists at the Center for Cancer Prevention Research, at Rutgers Ernest Mario School of Pharmacy, and the Cancer Institute of New Jersey, believe that two forms of vitamin E - gamma and delta-tocopherols - found in soybean, canola and corn oils as well as nuts do prevent colon, lung, breast and prostate cancers.
"There are studies suggesting that vitamin E actually increases the risk of cancer and decreases bone density," says Chung S. Yang, director of the center. "Our message is that the vitamin E form of gamma-tocopherols, the most abundant form of vitamin E in the American diet, and delta-tocopherols, also found in vegetable oils, are beneficial in preventing cancers while the form of vitamin E, alpha- tocopherol, the most commonly used in vitamin E supplements, has no such benefit."
Yang and colleagues, Nanjoo Suh and Ah-Ng Tony Kong, summarized their findings recently in Cancer Prevention Research, a journal of the American Association for Cancer Research. In a Commentary, "Does Vitamin E Prevent or Promote Cancer?" the Rutgers scientists discuss animal studies done at Rutgers as well as human epidemiological studies that have examined the connection between vitamin E and cancer.
Yang says Rutgers scientists conducting animal studies for colon, lung, breast and prostate cancer found that the forms of vitamin E in vegetable oils, gamma and delta-tocopherols, prevent cancer formation and growth in animal models.
"When animals are exposed to cancer-causing substances, the group that was fed these tocopherols in their diet had fewer and smaller tumors," Yang says. "When cancer cells were injected into mice these tocopherols also slowed down the development of tumors."
In researching colon cancer, Yang pointed to another recently published paper in Cancer Prevention Research indicating that the delta-tocopherol form of vitamin E was more effective than other forms of vitamin E in suppressing the development of colon cancer in rats.
This is good news for cancer research. Recently, in one of the largest prostate cancer clinical trials in the United States and Canada, scientists found that the most commonly used form of vitamin E supplements, alpha-tocopherol, not only did not prevent prostate cancer, but its use significantly increased the risk of this disease among healthy men.
This is why, Yang says, it is important to distinguish between the different forms of vitamin E and conduct more research on its cancer preventive and other biological effects.
"For people who think that they need to take vitamin E supplements," Yang says, "taking a mixture of vitamin E that resembles what is in our diet would be the most prudent supplement to take."
Rutgers, The State University of New Jersey
Related Vitamin E Current Events and Vitamin E News Articles
New study finds clear differences between organic and non-organic milk and meat
In the largest study of its kind, an international team of experts led by Newcastle University, UK, has shown that both organic milk and meat contain around 50% more beneficial omega-3 fatty acids than conventionally produced products.
Obese people need more vitamin E, but actually get less
A recent study suggests that obese people with metabolic syndrome face an unexpected quandary when it comes to vitamin E - they need more than normal levels of the vitamin because their weight and other problems are causing increased oxidative stress, but those same problems actually cause their effective use of vitamin E to be reduced.
Antioxidants cause malignant melanoma to metastasize faster
Fresh research at Sahlgrenska Academy has found that antioxidants can double the rate of melanoma metastasis in mice.
DNA/RNA heteroduplex oligonucleotide: The third class oligonucleotides
Heteroduplex oligonucleotide (HDO) is a brand new oligonucleotide drug, pioneered by researchers of Tokyo Medical and Dental University, Osaka University and ISIS. HDO is found to be significantly potent at reducing expression of the target RNA, and also improves the phenotype in disease models effectively.
Controlling inflammation to reduce chronic disease risk
An unresolved inflammatory response is likely to be involved from the early stages of disease development.
Scientists figure out how vitamin E keeps muscles healthy
Body builders have it right: vitamin E does help build strong muscles, and scientists appear to have figured out one important way it does it.
Link between vitamin E and exposure to air pollution
A new study from King's College London and the University of Nottingham has found an association between the amount of vitamin E in the body, exposure to particulate pollution and lung function.
Pooled analysis confirms vitamin E as a treatment for non-alcoholic steatohepatitis
Results revealed today at The International Liver Congress™ 2015 show that vitamin E (d-alpha-tocopherol) is an effective treatment for non-alcoholic steatohepatitis (NASH).
Dwindling bird populations in Fukushima
This is the time of year when birds come out and really spread their wings, but since a disastrous day just before spring's arrival four years ago, Japan's Fukushima province has not been friendly to the feathered.
Obesity associated with prostate cancer risk in African-American men
Obesity was associated with an increased risk for prostate cancer in African American men and that risk grew by nearly four times as body-mass index (BMI) increased, according to an article published online by JAMA Oncology.
More Vitamin E Current Events and Vitamin E News Articles