Science Current Events | Science News | Brightsurf.com
 

Algae extract increases good cholesterol levels, Wayne State research finds

July 09, 2012
Detroit - A Wayne State University researcher has found that an extract from algae could become a key to regulating cardiovascular disease.

In a study funded by Health Enhancement Products of Bloomfield Hills, Mich., Smiti Gupta, Ph.D., assistant professor in the department of nutrition and food science in the College of Liberal Arts and Sciences, has found that dietary intake of ProAlgaZyme increased the level of high-density lipoprotein (HDL) in an animal model.

While medications for the control of high plasma cholesterol levels such as statins and numerous dietary supplements primarily function by lowering levels of low-density lipoproteins (LDL), or "bad cholesterol," Gupta's research explores the effects of raising levels of HDL, or "good cholesterol," which work in part by carrying cholesterol out of the arterial wall.

Results of her study, titled "ProAlgaZyme and its Sub-fractions Increase Plasma HDL-Cholesterol via Up Regulation of ApoA1, ABCA1 and SRB1 and Inhibition of CETP in Hypercholesterolemic Hamsters," were published recently in the Journal of Nutrition and Dietary Supplements.

"The cholesterol mechanism is crucial to heart disease," Gupta said. "Very few agents increase good cholesterol, but we found that this algae extract does. The ratio of total to HDL cholesterol improved significantly. This result, if replicated in humans, would be consistent with a decreased risk of heart disease."

ProAlgaZyme, a clear liquid, was administered as part of the drinking fluid over four weeks. In addition to increasing HDL levels, the group found that it also changed the expression of genes involved in the reverse cholesterol transport mechanism. And while they don't know exactly how it will function in humans, Gupta said other research suggests a similar outcome.

"Its biological effect over time and toxic effects, if any, need to be further investigated in a long-term study in an animal model before testing its effects in humans," she said. "But this is a step in the right direction, since increased HDL is considered an important therapeutic target for improvement of the lipid profile and thus reduction of the risk for cardiovascular disease."

Wayne State University - Office of the Vice President for Research


Related Cholesterol Current Events and Cholesterol News Articles


Poor diabetes control found in older Americans
Only one in three older Americans have their diabetes under control as measured by guidelines set by the American Diabetes Association, new Johns Hopkins Bloomberg School of Public Health research suggests.

Cholesterol metabolism in immune cells linked to HIV progression, may lead to new therapy
Enhanced cholesterol metabolism in certain immune cells may help some people infected with HIV naturally control disease progression, according to new research from the University of Pittsburgh Graduate School of Public Health.

Cholesterol metabolism in immune cells linked to HIV progression
Lower levels of cholesterol in certain immune cells--a result of enhanced cholesterol metabolism within those cells--may help explain why some HIV-infected people are able to naturally control disease progression.

Novel treatments emerging for human mitochondrial diseases
Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.

Hypertension, high cholesterol, other heart disease risk factors increasing In Asia
The prevalence of cardiovascular risk factors like hypertension, high cholesterol, and diabetes have been decreasing in the United States and Europe, however they appear to be on the rise in Asia, particularly Japan, according to a guest editor page published today in the Journal of the American College of Cardiology.

Study: Restaurant meals can be as bad for your waistline as fast food is
When Americans go out to eat, either at a fast-food outlet or a full-service restaurant, they consume, on average, about 200 more calories a day than when they stay home for meals, a new study reports.

To shed weight, go vegan
People on a vegetarian diet, and especially those following a vegan one that includes no animal products, see better results than dieters on other weight-reducing plans.

SLU scientists develop potential new class of cancer drugs in lab
In research published in Cancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting the Warburg Effect, a trait of cancer cell metabolism that scientists have been eager to exploit.

Nearly half of Hispanics unaware they have high cholesterol; less than a third treated
Nearly half of Hispanic adults were unaware they have high cholesterol, and less than a third receive any kind of cholesterol treatment, in a new study in Journal of the American Heart Association.

Nanoparticle 'wrapper' delivers chemical that stops fatty buildup in rodent arteries
In what may be a major leap forward in the quest for new treatments of the most common form of cardiovascular disease, scientists at Johns Hopkins report they have found a way to halt and reverse the progression of atherosclerosis in rodents by loading microscopic nanoparticles with a chemical that restores the animals' ability to properly handle cholesterol.
More Cholesterol Current Events and Cholesterol News Articles

The Great Cholesterol Myth: Why Lowering Your Cholesterol Won't Prevent Heart Disease-and the Statin-Free Plan That Will

The Great Cholesterol Myth: Why Lowering Your Cholesterol Won't Prevent Heart Disease-and the Statin-Free Plan That Will
by Jonny Bowden (Author), Stephen Sinatra (Author)


Heart disease is the #1 killer. However, traditional heart disease protocols--with their emphasis on lowering cholesterol--have it all wrong. Emerging science is showing that cholesterol levels are a poor predictor of heart disease and that standard prescriptions for lowering it, such as ineffective low-fat/high-carb diets and serious, side-effect-causing statin drugs, obscure the real causes of heart disease. Even doctors at leading institutions have been misled for years based on creative reporting of research results from pharmaceutical companies intent on supporting the $31-billion-a-year cholesterol-lowering drug industry.The Great Cholesterol Myth reveals the real culprits of heart disease, including:
Inflammation
Fibrinogen
Triglycerides
Homocysteine
Belly...

Cholesterol Down: Ten Simple Steps to Lower Your Cholesterol in Four Weeks--Without Prescription Drugs

Cholesterol Down: Ten Simple Steps to Lower Your Cholesterol in Four Weeks--Without Prescription Drugs
by Janet Brill (Author)


Take Control of Your Cholesterol— Without Drugs

If you are one of the nearly 100 million Americans struggling with high cholesterol, then Dr. Janet Brill offers you a revolutionary new plan for taking control of your health—without the risks of statin drugs. With Dr. Brill’s breakthrough Cholesterol Down Plan, you simply add nine “miracle foods” to your regular diet and thirty minutes of walking to your daily routine. That’s all. This straightforward and easy-to-follow program can lower your LDL (“bad”) cholesterol by as much as 47 percent in just four weeks.

Cholesterol Down explains Dr. Brill’s ten-point plan as well as the science behind it. You’ll learn how each miracle food affects LDL cholesterol and how the foods work together for maximum effect,...

The Cholesterol Solution Guide: Lower Your Cholesterol in 30 Days Without Drugs

The Cholesterol Solution Guide: Lower Your Cholesterol in 30 Days Without Drugs
by Michael E. Reese (Author)


Discover How Easy It Is To Lower Your Cholesterol in 30 DAYS This book will tell you what cholesterol is, its signs, symptoms, causes, and types, so that you will be aware of the need to reduce your LDL or bad cholesterol levels and increase the HDL or good cholesterol levels. This book contains proven steps and strategies on how to lower your cholesterol the natural way in just 30 days. ORDER Your Copy Today!

Cholesterol is Not the Culprit: A Guide to Preventing Heart Disease

Cholesterol is Not the Culprit: A Guide to Preventing Heart Disease
by Dr Fred Kummerow (Author)


You will find a lot in this book related to diet and heart disease; it is the number one cause of death in the U.S. and throughout much of the world and also the focus of the majority of my career. To me, researching diet and heart disease is like being the detective in a good mystery book who follows clue after clue and finally comes up with an unexpected answer. The detective is always trying to find out who and what killed the person. Some detectives view cholesterol as the killer in heart disease, but I show you why that's not so. I hope in reading this book, you'll not only learn what is healthy to eat, but also why it is healthy to do so. How the body uses food to make what we need to keep going is an incredible, almost magical, process. We, as well as all animals and plants, are...

Controlling Cholesterol For Dummies

Controlling Cholesterol For Dummies
by Carol Ann Rinzler (Author), Martin W. Graf (Contributor)


Need to get your cholesterol in check? You’ll find the latest information about cholesterol, including treatments, drug information, and dietary advice, in Controlling Cholesterol For Dummies, 2nd Edition, an easy-to-understand guide to cholesterol control. You’ll learn how to lower your numbers and maintain healthy cholesterol levels. You’ll also find out how to eat and exercise properly, use vitamins and supplements, and quit unhealthy habits. You’ll find out cholesterol’s positive functions and why too much can be a bad thing. You can also assess your cholesterol risk by taking your age, sex, ethnicity, and family history into consideration. Find out what you need to ask your doctor about stress tests, ECBT, and angiograms to check for plaque buildup. Design a...

Cholesterol Clarity: What The HDL Is Wrong With My Numbers?

Cholesterol Clarity: What The HDL Is Wrong With My Numbers?
by Jimmy Moore (Author), Eric C. Westman (Author)


Are you confused by what your cholesterol levels really say about your health?

Don't you wish someone could just spell it out in simple, easy-to-understand language and tell you what, if anything, you need to do about your cholesterol? Good news! That's precisely what Cholesterol Clarity is designed to do. Jimmy Moore, a prominent and highly respected health blogger and podcaster, has teamed up with Dr. Eric Westman, a practicing internist and nutrition researcher, to bring you one of the most unique books you'll ever read on this subject, featuring exclusive interviews with twenty-nine of the world's top experts from various fields to give you the complete lowdown on cholesterol. If you're worried about any confusing medical jargon in this book, don't be—this critical...

The Truth About Statins: Risks and Alternatives to Cholesterol-Lowering Drugs

The Truth About Statins: Risks and Alternatives to Cholesterol-Lowering Drugs
by Barbara H. Roberts M.D. (Author)


COULD STATIN DRUGS ACTUALLY HARM YOU?

Despite the rosy picture painted in the ads of a miracle cure for high cholesterol and its attendant heart disease, the reality of taking statins may be far less pretty. Dr. Barbara H. Roberts, director of the Women’s Cardiac Center at the Miriam Hospital in Rhode Island, discusses both the benefits and health risks of these popular drugs in this comprehensive guide that finally reveals the questionable science behind the research studies. This honest, patient-friendly appraisal of the most widely used medications in the world may shock you, but it may also save your life.

Offering clear-cut, easy-to-understand information in an easily accessible fashion, Dr. Roberts explains how to take the best possible care of your heart,...

American Heart Association Low-Fat, Low-Cholesterol Cookbook, 4th edition: Delicious Recipes to Help Lower Your Cholesterol

American Heart Association Low-Fat, Low-Cholesterol Cookbook, 4th edition: Delicious Recipes to Help Lower Your Cholesterol
by American Heart Association (Author)


Eat wisely, eat well.

The nation’s most trusted authority on heart-healthy living presents the fourth edition of this classic cookbook, with the most up-to-date information on heart health and nutrition—including the effects of saturated and trans fats and cholesterol—and 50 exciting new recipes.

American Heart Association Low-Fat, Low-Cholesterol Cookbook offers more than 200 delicious, easy-to-prepare dishes, including:

•Fresh Basil and Kalamata Hummus
•Elegant Beef Tenderloin
•Tilapia Tacos with Fresh Salsa
•Garlic Chicken Fillets in Balsamic Vinegar
•Peppery Beef with Blue Cheese Sauce
•Thai Coconut Curry with Vegetables
•Sweet Potatoes in Creamy Cinnamon Sauce
•Pumpkin-Pie Coffeecake
•Streusel-Topped Blueberry...

Cholesterol:The Great Cholesterol Hoax: Why Cholesterol Lowering Drugs Won't Help You Live One Day Longer And Drug Companies Know It (Cholesterol diet,Cholesterol ... Cholesterol lowering foods,heart disease)

Cholesterol:The Great Cholesterol Hoax: Why Cholesterol Lowering Drugs Won't Help You Live One Day Longer And Drug Companies Know It (Cholesterol diet,Cholesterol ... Cholesterol lowering foods,heart disease)


The Great Cholesterol Hoax: Why Cholesterol Lowering Drugs Won't Help You Live One Day Longer And Drug Companies Know It
Today only, get this amazingly informative and very popular book on cholesterol for just $3.33 Regularly priced at $6.99. Read on your PC, Mac, smart phone, tablet or Kindle device.

What if everything you've been told about cholesterol was lie, invented to benefit the drug makers?
You are about to discover the real truth behind America’s number #1 killer today that outweighs all cancers combined as the country’s biggest mass murderer to date. Over 600,000 people a year are killed by heart attacks.

Cholesterol medicine (statins) are now the world's most-prescribed form of medications. It is estimated that one in four Americans...

Low Cholesterol Diet: How To Lower Your Cholesterol Naturally to Prevent and Reverse Heart Disease (Low Fat Low Cholesterol Cookbook, Congenital Heart ... Disease for Dummies, Reversing Heart Disease)

Low Cholesterol Diet: How To Lower Your Cholesterol Naturally to Prevent and Reverse Heart Disease (Low Fat Low Cholesterol Cookbook, Congenital Heart ... Disease for Dummies, Reversing Heart Disease)
by MD Martha McDowell (Author)


Reduce Your Cholesterol Naturally for $9.99 only This book will be priced at $14.99 SOON. Don't lose the moment! This book is filled with healthy recipes and tips on how to reduce your cholesterol. When writing this book our main target was to help you to reduce your cholesterol naturally and not “torturing” you and your body with classic weight losing diet. Moreover cholesterol is not about limiting your meal; it’s about replacement of fats with healthy food products and changing your lifestyle. Reducing cholesterol naturally requires a complex approach to what you eat and do in your everyday life. The book will help and guide you through this process and will provide you with useful tips and diet recipes that will help you to decrease the level of cholesterol in your blood...

© 2015 BrightSurf.com