Science Current Events | Science News | Brightsurf.com
 

Algae extract increases good cholesterol levels, Wayne State research finds

July 09, 2012
Detroit - A Wayne State University researcher has found that an extract from algae could become a key to regulating cardiovascular disease.

In a study funded by Health Enhancement Products of Bloomfield Hills, Mich., Smiti Gupta, Ph.D., assistant professor in the department of nutrition and food science in the College of Liberal Arts and Sciences, has found that dietary intake of ProAlgaZyme increased the level of high-density lipoprotein (HDL) in an animal model.

While medications for the control of high plasma cholesterol levels such as statins and numerous dietary supplements primarily function by lowering levels of low-density lipoproteins (LDL), or "bad cholesterol," Gupta's research explores the effects of raising levels of HDL, or "good cholesterol," which work in part by carrying cholesterol out of the arterial wall.

Results of her study, titled "ProAlgaZyme and its Sub-fractions Increase Plasma HDL-Cholesterol via Up Regulation of ApoA1, ABCA1 and SRB1 and Inhibition of CETP in Hypercholesterolemic Hamsters," were published recently in the Journal of Nutrition and Dietary Supplements.

"The cholesterol mechanism is crucial to heart disease," Gupta said. "Very few agents increase good cholesterol, but we found that this algae extract does. The ratio of total to HDL cholesterol improved significantly. This result, if replicated in humans, would be consistent with a decreased risk of heart disease."

ProAlgaZyme, a clear liquid, was administered as part of the drinking fluid over four weeks. In addition to increasing HDL levels, the group found that it also changed the expression of genes involved in the reverse cholesterol transport mechanism. And while they don't know exactly how it will function in humans, Gupta said other research suggests a similar outcome.

"Its biological effect over time and toxic effects, if any, need to be further investigated in a long-term study in an animal model before testing its effects in humans," she said. "But this is a step in the right direction, since increased HDL is considered an important therapeutic target for improvement of the lipid profile and thus reduction of the risk for cardiovascular disease."

Wayne State University - Office of the Vice President for Research


Related Cholesterol Current Events and Cholesterol News Articles


Dialysis patients may have faulty 'good' cholesterol
Kidney disease patients on dialysis often have impaired high-density lipoprotein (HDL) or "good" cholesterol, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

Antidepressants linked with improved cardiovascular outcomes
A new study scheduled for presentation at a meeting of the American College of Cardiology found that screening for and treating depression could help to reduce the risk of heart disease in patients with moderate to severe depression.

Study bolsters link between heart disease, excessive sitting
Coronary artery disease is the most common type of heart disease and the leading cause of death in the United States.

New study links antidepressants with improved cardiovascular outcomes
A new study by researchers at the Intermountain Medical Center Heart Institute has found that screening for and treating depression could help to reduce the risk of heart disease in patients with moderate to severe depression.

New studies fail to find cardiovascular risk with testosterone therapy
Two studies scheduled for presentation at the American College of Cardiology's 64th Annual Scientific Session in San Diego failed to find a connection between testosterone therapy in men and heart problems, contradicting research that prompted the U.S. Food and Drug Administration to investigate its safety.

Mediterranean diet cuts heart disease risk by nearly half
Adults who closely followed the Mediterranean diet were 47 percent less likely to develop heart disease over a 10-year period compared to similar adults who did not closely follow the diet.

Friends may make the difference in keeping children active
Children being physically active with a friend may accomplish more than hearing encouragement or being active with a parent, according to a new study presented at the American Heart Association's Epidemiology/Lifestyle Scientific Sessions 2015.

Study shows who benefits most from statins
New research suggests that widely used statin therapy provides the most benefit to patients with the highest genetic risk of heart attack.

Preventing metabolic disease may start in the womb... of your grandmother
No one wants to have child who is born underweight, but for numerous reasons, this may be unavoidable.

Study shows strong link between adolescent obesity and high blood pressure
A recent study published in the American Journal of Hypertension has found that body mass index (BMI) in healthy adolescents has a statistically significant association with both systolic blood pressures (SBP) and diastolic blood pressures (DBP), and highlights the significance of the global trend of rapidly increasing adolescent obesity.
More Cholesterol Current Events and Cholesterol News Articles

The Great Cholesterol Myth: Why Lowering Your Cholesterol Won't Prevent Heart Disease-and the Statin-Free Plan That Will

The Great Cholesterol Myth: Why Lowering Your Cholesterol Won't Prevent Heart Disease-and the Statin-Free Plan That Will
by Jonny Bowden (Author), Stephen Sinatra (Author)


Heart disease is the #1 killer. However, traditional heart disease protocols--with their emphasis on lowering cholesterol--have it all wrong. Emerging science is showing that cholesterol levels are a poor predictor of heart disease and that standard prescriptions for lowering it, such as ineffective low-fat/high-carb diets and serious, side-effect-causing statin drugs, obscure the real causes of heart disease. Even doctors at leading institutions have been misled for years based on creative reporting of research results from pharmaceutical companies intent on supporting the $31-billion-a-year cholesterol-lowering drug industry.The Great Cholesterol Myth reveals the real culprits of heart disease, including:
Inflammation
Fibrinogen
Triglycerides
Homocysteine
Belly...

Cholesterol Down: Ten Simple Steps to Lower Your Cholesterol in Four Weeks--Without Prescription Drugs

Cholesterol Down: Ten Simple Steps to Lower Your Cholesterol in Four Weeks--Without Prescription Drugs
by Janet Brill (Author)


Take Control of Your Cholesterol— Without Drugs

If you are one of the nearly 100 million Americans struggling with high cholesterol, then Dr. Janet Brill offers you a revolutionary new plan for taking control of your health—without the risks of statin drugs. With Dr. Brill’s breakthrough Cholesterol Down Plan, you simply add nine “miracle foods” to your regular diet and thirty minutes of walking to your daily routine. That’s all. This straightforward and easy-to-follow program can lower your LDL (“bad”) cholesterol by as much as 47 percent in just four weeks.

Cholesterol Down explains Dr. Brill’s ten-point plan as well as the science behind it. You’ll learn how each miracle food affects LDL cholesterol and how the foods work together for maximum effect,...

Cholesterol Clarity: What The HDL Is Wrong With My Numbers?

Cholesterol Clarity: What The HDL Is Wrong With My Numbers?
by Jimmy Moore (Author), Eric C. Westman (Author)


Are you confused by what your cholesterol levels really say about your health?

Don't you wish someone could just spell it out in simple, easy-to-understand language and tell you what, if anything, you need to do about your cholesterol? Good news! That's precisely what Cholesterol Clarity is designed to do. Jimmy Moore, a prominent and highly respected health blogger and podcaster, has teamed up with Dr. Eric Westman, a practicing internist and nutrition researcher, to bring you one of the most unique books you'll ever read on this subject, featuring exclusive interviews with twenty-nine of the world's top experts from various fields to give you the complete lowdown on cholesterol. If you're worried about any confusing medical jargon in this book, don't be—this critical...

Cholesterol:The Great Cholesterol Hoax: Why Cholesterol Lowering Drugs Won't Help You Live One Day Longer And Drug Companies Know It (Cholesterol diet,Cholesterol ... Cholesterol lowering foods,heart disease)

Cholesterol:The Great Cholesterol Hoax: Why Cholesterol Lowering Drugs Won't Help You Live One Day Longer And Drug Companies Know It (Cholesterol diet,Cholesterol ... Cholesterol lowering foods,heart disease)


The Great Cholesterol Hoax: Why Cholesterol Lowering Drugs Won't Help You Live One Day Longer And Drug Companies Know It
Today only, get this amazingly informative and very popular book on cholesterol for just $3.23. Regularly priced at $4.99. Read on your PC, Mac, smart phone, tablet or Kindle device.

What if everything you've been told about cholesterol was lie, invented to benefit the drug makers?
You are about to discover the real truth behind America’s number #1 killer today that outweighs all cancers combined as the country’s biggest mass murderer to date. Over 600,000 people a year are killed by heart attacks.

Cholesterol medicine (statins) are now the world's most-prescribed form of medications. It is estimated that one in four Americans...

Cholesterol is Not the Culprit: A Guide to Preventing Heart Disease

Cholesterol is Not the Culprit: A Guide to Preventing Heart Disease
by Dr Fred Kummerow (Author)


You will find a lot in this book related to diet and heart disease; it is the number one cause of death in the U.S. and throughout much of the world and also the focus of the majority of my career. To me, researching diet and heart disease is like being the detective in a good mystery book who follows clue after clue and finally comes up with an unexpected answer. The detective is always trying to find out who and what killed the person. Some detectives view cholesterol as the killer in heart disease, but I show you why that's not so. I hope in reading this book, you'll not only learn what is healthy to eat, but also why it is healthy to do so. How the body uses food to make what we need to keep going is an incredible, almost magical, process. We, as well as all animals and plants, are...

The Cholesterol Solution Guide: Lower Your Cholesterol in 30 Days Without Drugs

The Cholesterol Solution Guide: Lower Your Cholesterol in 30 Days Without Drugs
by Michael E. Reese (Author)


Discover How Easy It Is To Lower Your Cholesterol in 30 DAYS This book will tell you what cholesterol is, its signs, symptoms, causes, and types, so that you will be aware of the need to reduce your LDL or bad cholesterol levels and increase the HDL or good cholesterol levels. This book contains proven steps and strategies on how to lower your cholesterol the natural way in just 30 days. ORDER Your Copy Today!

Cholesterol Diet: The Ultimate Solution to Lower Your Cholesterol Without Drug (Weight Loss Motivation Strategies, Cholesterol Solution, Lower Cholesterol Naturally, Heart Disease Prevention)

Cholesterol Diet: The Ultimate Solution to Lower Your Cholesterol Without Drug (Weight Loss Motivation Strategies, Cholesterol Solution, Lower Cholesterol Naturally, Heart Disease Prevention)
by Weight Loss Motivation - Healthy Weight Loss Diet


The Ultimate Solution to Lower Your Cholesterol Without Drug
Cholesterol is an important substance that your body need. There are 3 types of cholesterol – the bad cholesterol (LDL), good cholesterol (HDL) and triglycerides. If your bad cholesterol level is higher than the normal level in your bloodstream, it causes blockage of your arteries. However, there are things that you can do to manage cholesterol levels and lower your risk.

High cholesterol is one of the health problems that are affecting millions of people all over the world. It is considered as one of the major risk factors for heart disease. You will have difficulties in dealing with it if you are not aware what cholesterol is. There are lots of myths and misconceptions about cholesterol, which worsen...

The Truth About Statins: Risks and Alternatives to Cholesterol-Lowering Drugs

The Truth About Statins: Risks and Alternatives to Cholesterol-Lowering Drugs
by Barbara H. Roberts M.D. (Author)


COULD STATIN DRUGS ACTUALLY HARM YOU?

Despite the rosy picture painted in the ads of a miracle cure for high cholesterol and its attendant heart disease, the reality of taking statins may be far less pretty. Dr. Barbara H. Roberts, director of the Women’s Cardiac Center at the Miriam Hospital in Rhode Island, discusses both the benefits and health risks of these popular drugs in this comprehensive guide that finally reveals the questionable science behind the research studies. This honest, patient-friendly appraisal of the most widely used medications in the world may shock you, but it may also save your life.

Offering clear-cut, easy-to-understand information in an easily accessible fashion, Dr. Roberts explains how to take the best possible care of your heart,...

Ignore the Awkward.: How the Cholesterol Myths Are Kept Alive

Ignore the Awkward.: How the Cholesterol Myths Are Kept Alive
by Uffe Ravnskov (Author)


The cholesterol campaign is the greatest medical scandal in modern time. If you have read the author's previous books ´The Cholesteol Myths´ (out of print) or 'Fat and Cholesterol are GOOD for You', you should know that for certain. For instance, according to more than 25 scientific studies old people with high cholesterol live the longest. Another shocking fact is that the authors of a recent American study of more than 130,000 patients with acute myocardial infarction found that on average, their cholesterol was lower than normally. Their finding has already been confirmed by others. What they also found was that three years later, mortality was twice as high among those whose cholesterol was the lowest. Their conclusion? We must lower cholesterol even more! But there is much, much...

Cholesterol: The Ultimate Cholesterol Solution: Lower Your Cholesterol Naturally In Less Than 4 Weeks (Cholesterol Diet, Cholesterol Recipes, Cholesterol Down, Meals Plan)

Cholesterol: The Ultimate Cholesterol Solution: Lower Your Cholesterol Naturally In Less Than 4 Weeks (Cholesterol Diet, Cholesterol Recipes, Cholesterol Down, Meals Plan)


Discover How To Lower Cholesterol in Less Than 4 Weeks Without Drugs
* * *LIMITED TIME OFFER! 50% OFF! (Regular Price $5.99)* * *

By Reading This Book You Will Learn How to Lower Cholesterol With a 7-Day Meal Plan
Read on your PC, Mac, smart phone, tablet or Kindle device.

Cholesterol is a fatty substance which is not soluble in water and therefore isn’t found normally in our blood being insoluble in it. They are transported through the bloodstream with lipoproteins which act as a carrier.
Even if the bad cholesterol is naturally present within a human body, the concentration of this can increase exponentially by the food that we eat. Food which are high in cholesterol, saturates and trans fat are the major contributors to the increased HDL...

© 2015 BrightSurf.com