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Report: Strategies to prevent noise-induced hearing loss, tinnitus in soldiers
September 07, 2012
DETROIT - Antioxidants, dietary supplements and high-tech brain imaging are among some of the novel strategies that may help detect, treat and even prevent noise-induced hearing loss and tinnitus among American troops, according to researchers at Henry Ford Hospital. A culmination of nearly 25 years of research on noise-induced hearing loss - a growing medical issue that affects more than 12 percent of American troops returning from conflicts around the globe - will be presented Sept. 9 at the American Academy of Otolaryngology-Head & Neck Surgery annual meeting in Washington, D.C. Led by Michael Seidman, M.D., the research team is the first to identify how acoustic trauma from machinery and explosive devices damages the inner ear cells and breaks down cell growth, much like age-related hearing loss. "Improvised explosive devices, aircraft and other weaponry being used by the military are frankly deafening our troops," says Dr. Seidman, director of the Division of Otologic/Neurotologic Surgery in the Department of Otolaryngology-Head & Neck Surgery at Henry Ford Hospital. "Noise-induced hearing loss doesn't just impact a person's ability to hear; it can cause balance issues, make it difficult to sleep and communicate, and even raise the risk for heart disease by increasing a person's blood pressure, lipids and blood sugar." As part of his presentation, Dr. Seidman will explain how noise-induced hearing loss, as well as tinnitus-related traumatic brain injury, occurs based on research from Wayne State University's Jinsheng Zhang, Ph.D. Dr. Zhang has developed a model of blast-induced tinnitus and hearing loss using a shock tube that generates a 194 decibel shock wave similar to many of the explosive devices being deployed against troops. Further, Dr. Seidman will discuss the use of nutraceuticals, such as acetyl-l-carnitine, alpha lipoic acid and resveratrol - a substance found in red wine and red grapes - to mitigate hearing-related issues. Based on initial results, Dr. Seidman says a nutraceutical with a resveratrol-based component may possibly hold the potential to not only prevent, but reverse hearing loss in certain circumstances for soldiers. This research is based on animal models, but will soon be tested with humans, to see if a pill could soon be developed to prevent acoustic trauma in troops. In addition, Dr. Seidman will highlight new research on tinnitus, a chronic ringing of the head or ears that affects more than 50 million patients. A study co-authored by Susan Bowyer, Ph.D., senior bioscientific researcher at Henry Ford Hospital, found that an imaging technique called magnetoencephalography (MEG) can determine the site of perception of tinnitus in the brain, which could in turn allow physicians to target the area with electrical or chemical therapies to lessen symptoms. Although is no cure for tinnitus, several interventions are available, including dietary modification, the use of specific herbs and supplements, sound therapies, centrally acting medications and electrical stimulation of the cochlea and brain using implantable electrodes and an implantable pulse generator. To date, Dr. Seidman has treated six patients with direct electrical stimulation to the brain, reducing the tinnitus in four of those patients. In all, the team's work on noise-induced hearing loss and tinnitus has led to more than 50 peer-reviewed publications and several patents. According to Dr. Seidman, more research and funding are needed in order to generate critical data to facilitate an understanding of the damage caused by acoustic trauma and develop strategies to mitigate that damage. Henry Ford Health System Related Hearing Loss Current Events and Hearing Loss News ArticlesWomen with chronic physical disabilities are no less likely to bear childrenLike the general public, health care professionals may hold certain stereotypes regarding sexual activity and childbearing among women with disabilities. Research on cilia heats up: Implications for hearing, vision loss and kidney diseaseExperiments at Johns Hopkins have unearthed clues about which protein signaling molecules are allowed into hollow, hair-like "antennae," called cilia, that alert cells to critical changes in their environments. Effect of different oxygen saturation levels on death or disability in extremely preterm infantsIn a randomized trial performed to help resolve the uncertainty about the optimal oxygen saturation therapy in extremely preterm infants, researchers found that targeting saturations of 85 percent to 89 percent compared with 91 percent to 95 percent had no significant effect on the rate of death or disability at 18 months. Concert cacophony: Short-term hearing loss protective, not damagingContrary to conventional wisdom, short-term hearing loss after sustained exposure to loud noise does not reflect damage to our hearing: instead, it is the body's way to cope. Researchers create map of 'shortcuts' between all human genesSome diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the single causative gene. Researchers advance fight against biggest hidden virusA virus that most people have probably never heard of, yet most of us carry, is the number 1 infectious cause of congenital birth defects. Researchers advance fight against leading infectious cause of congenital birth defectsA virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero development, 1 in 750 children are born with or develop permanent disabilities such as hearing loss or brain damage. But efforts to develop a first-ever CMV vaccine are gaining ground. Rapid hearing loss may be a symptom of rare Creutzfeldt-Jakob DiseaseRapid hearing loss in both ears may be a symptom of the rare but always-fatal Creutzfeldt-Jakob Disease and should be considered a reason for clinicians to test for the disorder. Research leads to better understanding of peripheral neuropathyOne in 25,000 people worldwide is affected by neurofibromatosis type 2 (NF2), a condition where the loss of a tumour suppressor called Merlin results in multiple tumours in the brain and nervous system. Now hear this: Stanford researchers identify forerunners of inner-ear cells that enable hearing Researchers at the Stanford University School of Medicine have identified a group of progenitor cells in the inner ear that can become the sensory hair cells and adjacent supporting cells that enable hearing. More Hearing Loss Current Events and Hearing Loss News Articles

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