IntegraGen to take a leading role in unraveling the genetics of obesity in a EUR14.5M EU funded programJanuary 28, 2005IntegraGen, the personalized medicines company, is to take a significant role in the DiOgenes (Diet, Obesity and Genes) project. IntegraGen is one of a consortium of 30 EU organizations that has been awarded EUR14.5M to carry out a coordinated investigation into a broad range of factors influencing weight gain, from diet intervention to gene nutrient interactions. IntegraGen will, in collaboration with the INSERM consortium on the Functional Genomics of Obesity, be responsible for the genetic aspects of the project. Dr Jörg Hager, CSO of IntegraGen commented: "As a leader in the field of complex disease genetics, IntegraGen can play a key role in this project that seeks to explore the interaction of diet and genes on weight gain. Obesity is a health issue of increasing concern for Western societies. IntegraGen has already established a long heritage of ground-breaking work in the field of obesity genetics, having already identified five genes associated with the condition. We are looking forward to bringing our expertise to this innovative project." DiOgenes aims to respond to the challenge of obesity by involving a wide-range of different scientific and medical disciplines in a co-ordinated investigative project to gain a better understanding of obesity and its alleviation by dietary means. IntegraGen will be involved in an investigation of gene nutrient interactions that will enable the prediction of individual responses to nutrients and their impact on body weight. Ultimately, this will contribute to the development of personalized diet-based regimes. A DNA bank of over 13,000 individuals will form the basis of initial studies, with further analysis carried out on samples provided from longitudinal, multi-country, dietary studies.
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