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Sunlight reduces risk of lymph gland cancer
January 28, 2005A new study from Karolinska Institutet and Uppsala University shows that, contrary to previous belief, sunlight reduces the chances of developing tumours in the lymphatic glands (malignant lymphoma). The study is to be published in the next number of The Journal of the National Cancer Institute.
The number of new cases of lymphoma per year has tripled over the past 40 years, and the reasons are largely still a mystery. One hypothesis is that frequent exposure to the sun might increase the risk of developing this kind of cancer, especially the more common non-Hodgkin's form, but also the Hodgkin's type as well. However, a fresh study by research scientists at Karolinska Institutet and Uppsala University together with researchers from Denmark shows, on the contrary, that frequent exposure to ultraviolet rays, not only from the sun but also from sun lamps and solariums, seems to reduce the chances of developing Lymphoma, particularly non-Hodgkin's, by some 30-40 per cent.
"We find a similar correlation if we analyse responses by country or by skin-type," says Karin Ekström Smedby, postgraduate at KI's Department of Medical Epidemiology and Biostatistics. "This reduces the risk of systematic error and increases the credibility of our study."
The study was based on telephone interviews with more than 3,000 patients who were newly diagnosed as having malignant lymphoma, either non-Hodgkin's or Hodgkin's, between 1999 and 2002 in Sweden and Denmark, and just over 3,000 randomly chosen healthy members of the public. Participants were also asked about previous forms of diagnosed cancer.
Mechanisms unclear
It is already known that frequent exposure to the sun can increase the risk of skin cancer. If the results of this study can be replicated and complemented with additional data, Ms Ekström Smedby believes that advice about sunbathing might have to be amended.
"But we haven't looked into the mechanisms behind the effect of sunlight on lymphoma," she says. "More research is needed before we can give advice about the dangers and benefits of sunbathing in a wider perspective."
Researchers will now continue with other studies to identify the possible biological mechanisms behind this relationship.
Vetenskapsrådet (The Swedish Research Council)
The study was based on telephone interviews with more than 3,000 patients who were newly diagnosed as having malignant lymphoma, either non-Hodgkin's or Hodgkin's, between 1999 and 2002 in Sweden and Denmark, and just over 3,000 randomly chosen healthy members of the public. Participants were also asked about previous forms of diagnosed cancer.
Mechanisms unclear
It is already known that frequent exposure to the sun can increase the risk of skin cancer. If the results of this study can be replicated and complemented with additional data, Ms Ekström Smedby believes that advice about sunbathing might have to be amended.
"But we haven't looked into the mechanisms behind the effect of sunlight on lymphoma," she says. "More research is needed before we can give advice about the dangers and benefits of sunbathing in a wider perspective."
Researchers will now continue with other studies to identify the possible biological mechanisms behind this relationship.
Vetenskapsrådet (The Swedish Research Council)
Lymphoma Current Events and Lymphoma News RSSNew cancer target for non-Hodgkin's lymphoma
Physician-scientists from Weill Cornell Medical College have discovered a molecular mechanism that may prove to be a powerful target for the treatment of non-Hodgkin's lymphoma, a type of cancer that affects lymphocytes, or white blood cells.
Drugs to treat anemia in cancer patients linked to thromboembolism
Medications frequently given to cancer patients to reduce their risk of anemia are associated with an increased risk of deep vein thrombosis or pulmonary embolism, according to new research led by Dawn Hershman, M.D, M.S., co-director of the breast cancer program at the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center.
Researchers find new way to attack inflammation in Graves' eye disease
A small group of patients with severe Graves' eye disease experienced rapid improvement of their symptoms - and improved vision - following treatment with the drug rituximab.
Approved lymphoma drug shows promise in early tests against bone cancer
A drug already approved for the treatment of lymphoma may also slow the growth of the most deadly bone cancer in children and teens, according to an early-stage study published online today in the International Journal of Cancer.
Immunotherapy demonstrates long-term success in treating lymphoma
Targeted immunotherapy has been an attractive new therapeutic area for a number of cancers because it has the potential to destroy tumor cells without damaging surrounding normal tissue. New study results demonstrate high success rates using specialized white blood cells to prevent or treat lymphoma associated with the Epstein-Barr virus (EBV-lymphoma) in patients who have received a hematopoietic stem cell transplant (HSCT).
Exercise is good medicine for lymphoma patients
A healthy dose of exercise is good medicine, even for lymphoma patients receiving chemotherapy, University of Alberta researchers have found.
Childhood cancer survivors experience suicidal thoughts decades after diagnosis
Adult survivors of childhood cancer have an increased risk for suicidal thoughts, even decades after their cancer treatments ended, according to a study led by Dana-Farber Cancer Institute scientists.
New therapy for vasculitis will help patients avoid infertility and cancer
Researchers have identified that Rituxan, a drug previously approved for the treatment of non-Hodgkin's B cell lymphoma and rheumatoid arthritis, can treat severe ANCA-associated vasculitis as effectively as cyclophosphamide, the current standard therapy.
Studying cancer in pet dogs to find new treatments for human patients
A team of scientists at the National Cancer Institute (NCI) in Bethesda, USA, says that studying pet dogs with cancer could yield valuable information on how to diagnose and treat human cancers.
Scientists identify genetic cause of previously undefined primary immune deficiency disease
Researchers at the National Institutes of Health have identified a genetic mutation that accounts for a perplexing condition found in people with an inherited immunodeficiency.
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