Science Current Events | Science News | Brightsurf.com
 

Verifying that sorghum is a new safe grain for people with celiac disease

April 04, 2013

Strong new biochemical evidence exists showing that the cereal grain sorghum is a safe food for people with celiac disease, who must avoid wheat and certain other grains, scientists are reporting. Their study, which includes molecular evidence that sorghum lacks the proteins toxic to people with celiac disease, appears in ACS' Journal of Agricultural and Food Chemistry.

Paola Pontieri and colleagues explain that those gluten proteins, present in wheat and barley, trigger an immune reaction in people with celiac disease that can cause abdominal pain and discomfort, constipation, diarrhea and other symptoms. The only treatment is lifelong avoidance of gluten. Sorghum, they note, has emerged as an alternative grain for people with celiac disease. In Western countries, sorghum traditionally has been an animal feed. But in Africa and India, it long has been a food for people. Recently, U.S. farmers have begun producing sorghum hybrids that are a white grain, known as "food-grade" sorghum. The researchers set out to make a detailed molecular determination of whether sorghum contains those toxic gluten proteins.

They describe evidence from an analysis of the recently published sorghum genome, the complete set of genes in the plant, and other sources, that verify the absence of gluten proteins. The authors also report that sorghum has high nutritional value. "Food-grade sorghums should be considered as an important option for all people, especially celiac patients," the report concluded.

###

The authors acknowledge funding from the Regione Campania, the Istituto Banco di Napoli - Fondazione and the Compagnia di San Paolo.

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

American Chemical Society


Related Celiac Disease Current Events and Celiac Disease News Articles


Feeding at-risk infants gluten increases risk of developing celiac disease
Intake of gluten up until two years of age increases risk of celiac disease at least two-fold in children with genetic risk factors for this disease, according a study published in Clinical Gastroenterology and Hepatology the official clinical practice journal of the American Gastroenterological Association.

No increased dementia risk found in diagnosed celiac patients
A new and comprehensive study by investigators at the Celiac Disease Center at Columbia University Medical Center has found that celiac patients are at no increased risk for dementia before or after their diagnosis of celiac disease.

Researchers gauge heritability of childhood-onset autoimmune diseases
Scientists have calculated more precise measurements of heritability--the influence of underlying genes--in nine autoimmune diseases that begin in childhood.

Gut microorganisms cause gluten-induced pathology in mouse model of celiac disease
Investigators interested in celiac disease, a chronic gastrointestinal disorder caused by an immunologic response to the ingestion of gluten, have wondered why only 2% to 5% of genetically susceptible individuals develop the disease.

Genetic overlapping in multiple autoimmune diseases may suggest common therapies
Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets for treating many of these diseases, in some cases with existing drugs already available for non-autoimmune disorders.

Spouses & relatives of celiac disease patients at risk for autoimmune diseases
Both spouses and first-degree relatives of patients with celiac disease are at increased risk of nonceliac autoimmune disease, according to a study in the July issue of Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. This risk represents a mixture of genetic, environmental and ascertainment bias mechanisms.

New study finds that many probiotics are contaminated with traces of gluten
More than half of popular probiotics contain traces of gluten, according to an analysis performed by investigators at the Celiac Disease Center at Columbia University Medical Center (CUMC). Tests on 22 top-selling probiotics revealed that 12 of them (or 55%) had detectable gluten.

Definitive tests for irritable bowel syndrome developed at Cedars-Sinai
Millions of people afflicted by irritable bowel syndrome can now be diagnosed quickly and accurately with two simple blood tests developed by a Cedars-Sinai gastroenterologist.

Increased risk of neuropathy in patients with celiac disease
Celiac disease, which results from a sensitivity to gluten, was associated with a 2.5-fold increased risk of neuropathy (nerve damage), according to an article published online by JAMA Neurology.

Uncovering the effects of cooking, digestion on gluten and wheat allergens in pasta
Researchers trying to understand wheat-related health problems have found new clues to how the grain's proteins, including gluten, change when cooked and digested.
More Celiac Disease Current Events and Celiac Disease News Articles

Celiac Disease (Revised and Updated Edition): A Hidden Epidemic

Celiac Disease (Revised and Updated Edition): A Hidden Epidemic
by Peter H.R., M.D. Green (Author), Rory Jones (Author)


The definitive book on celiac disease, one of the most common and underdiagnosed autoimmune diseases in America, available in paperback for the first time.Do you suffer from gastrointestinal complaints, fatigue, headaches, joint pain, anemia, and/or itchy skin conditions? Have you consulted numerous doctors, and been prescribed drugs and diets that have only temporarily alleviated some symptoms? If so, you may have celiac disease, a hereditary autoimmune condition that affects nearly one in every hundred people—97 percent of whom remain undiagnosed and untreated.The real answer to your medical problems may lie in this book. Dr. Peter H.R. Green, director of the Celiac Disease Center at Columbia University and internationally renowned expert on the disease, together with Rory Jones, an...

Jennifer's Way: My Journey with Celiac Disease--What Doctors Don't Tell You and How You Can Learn to Live Again

Jennifer's Way: My Journey with Celiac Disease--What Doctors Don't Tell You and How You Can Learn to Live Again
by Jennifer Esposito (Author)


Celiac disease afflicts as many as one in 133 Americans. Unfortunately, 83 percent of them are undiagnosed or misdiagnosed, suffering through years of pain and misunderstanding. Award-winning actress Jennifer Esposito was one of them, only receiving an official diagnosis after decades of mysterious illnesses and misdiagnoses. In Jennifer’s Way, Esposito shares her personal journey, from her childhood in Brooklyn and years as a young actress to her struggle for an accurate diagnosis and quest to take charge of her health. She also offers critical tips and strategies for managing daily life with a chronic condition.

“[Esposito’s] rags-to-riches story will keep readers turning pages…The second section of the book is a helpful guide to living with celiac...

The First Year: Celiac Disease and Living Gluten-Free: An Essential Guide for the Newly Diagnosed

The First Year: Celiac Disease and Living Gluten-Free: An Essential Guide for the Newly Diagnosed
by Jules E. Dowler Shepard (Author)


If you’ve just been diagnosed with celiac disease, you’re not alone: as many as 1 in 133 Americans have this autoimmune disorder characterized by an inability to digest gluten, a protein found in wheat and other grains. For ten years, Jules Shepard’s gastrointestinal symptoms went misdiagnosed. Finally diagnosed, she experienced a rollercoaster of emotions and illness the year following, as she discovered what she could and could not eat through trial and error.Now, in The First Year®: Celiac Disease and Living Gluten-Free, Shepard explains everything you need to learn and do upon your or a family member’s diagnosis.

- How celiac disease affects your entire body

- Eating gluten-free (and avoiding hidden glutens)

- Keeping your kitchen...

Jump Start Your Gluten-Free Diet! Living with Celiac / Coeliac Disease & Gluten Intolerance

Jump Start Your Gluten-Free Diet! Living with Celiac / Coeliac Disease & Gluten Intolerance
by Gluten Free Passport


The University of Chicago Celiac Disease Center is dedicated to raising awareness, increasing diagnosis rates and meeting the needs of people affected by celiac disease nationwide through education, research and advocacy.

Celiac disease, spelled Coeliac outside of North America, is an autoimmune disorder, which means the body “attacks itself”, rather than attacking a foreign substance as in an allergy. The medical treatment for celiac disease consists of strict adherence to a gluten-free diet.

With this guide you will understand the differences between celiac disease, intolerances and allergies. You will learn about the 300-plus signs and symptoms associated with celiac disease, genetic and antibody blood testing, diagnosis and required follow-up...

Celiac Disease For Dummies

Celiac Disease For Dummies
by Ian Blumer (Author), Sheila Crowe (Author)


Celiac Disease For Dummies is the ultimate reference for people with the disease and their family members. The book helps readers identify symptoms of the disease, and explains how doctors definitively diagnose celiac disease. It outlines how celiac disease affects the body, and what its consequences could be if untreated. The authors explain how celiac disease is treated, not only through the elimination of gluten from the diet, but with additional nutritional measures and alternative and complementary therapies. Written by two practicing physicians, the book also offers practical, helpful guidance for parents of children with celiac disease, whose treatment may be a particular challenge.

Gluten Free Living For Health: How to Live with Celiac or Coeliac Disease (Gluten Intolerance Guide)

Gluten Free Living For Health: How to Live with Celiac or Coeliac Disease (Gluten Intolerance Guide)
by Weight A Bit


Changing to a gluten free diet can be overwhelming. Cooking food that is both gluten free and tasty is also a big challenge. Often foods do not taste as expected, or turn out to be difficult to create. By giving the reader a boxed set they will be able to create a variety of foods in different styles. This will let them learn what kind of gluten free foods taste best to them and also which foods are quickest and easiest to make. The boxed set gives the reader more choices and information so that they have the best experience.

Mayo Clinic Going Gluten Free: Essential Guide to Managing Celiac Disease and Related Conditions

Mayo Clinic Going Gluten Free: Essential Guide to Managing Celiac Disease and Related Conditions
by Joseph A. Murray (Author)


New from Mayo Clinic-the essential guide to living gluten-free. Whether diagnosed with celiac disease or just deciding if a gluten-free diet is right for you, Mayo Clinic Going Gluten-Free will help you create and maintain a gluten-free lifestyle. Both authoritative and approachable, the book includes core medical information on celiac disease in addition to focusing on practical, everyday issues, such as:

--Determining if gluten-free is right for you
--Common signs, symptoms and myths of celiac
--Dealing with celiac if you are newly diagnosed
--Maintaining a gluten-free lifestyle while traveling, during the holidays, on-the-go and at college
--Helping your child manage a gluten-free diet
--Properly reading and understanding food labels
--A few recipes and...

Celiac Disease: A Guide to Living with Gluten Intolerance

Celiac Disease: A Guide to Living with Gluten Intolerance
by Sylvia Llewelyn Bower RN (Author), Mary Kay Sharrett SM RD LD CNSD (Author), Steve Plogsted PharmD (Author)


Fully Revised and Updated An indispensable guide on how to safely alter your diet, manage your symptoms, and adjust to living gluten-free Celiac disease is an autoimmune disorder characterized by an inability to digest gluten, a protein found in wheat and other grains that affects as many as 1 in 133 Americans. Written by a nurse, dietician, and clinical pharmacist, Celiac Disease, Second Edition provides everything you need to know to live a healthy wheat-free and gluten-free lifestyle including how to: recognize and treat the most common symptoms eat gluten-free and avoid hidden glutens, especially in common medications prepare your kitchen and prevent cross-contamination cook and bake gluten-free including delicious, easy-to-prepare recipes for breads, breakfasts, main courses,...

7 Worst Mistakes People Make with Celiac Disease and Gluten: (and stay sick forever)

7 Worst Mistakes People Make with Celiac Disease and Gluten: (and stay sick forever)
by Black Wave Publishing


Hundreds of millions of people are suffering from thousands of medical issues and there are thousands of symptoms overlapping each other. It's a busy world. Where to start?! Who has time (or wants to) read thousands of pages on digestive problems, autoimmune diseases, and this very vague thing called Celiac / Coeliac Disease? Forget "50 Shades", it's more like 500 shades. But if you have a hint of an issue and are beginning your research - here's an easy read kept especially short so you can do it quickly, and know where to look out for where people generally go wrong. It's like talking to a contractor BEFORE you start shopping for houses, this way you know what to look out for.

How can we possibly read thousands of in-depth books to figure out what's going with us?! (yes,...

The Everything Gluten-Free Slow Cooker Cookbook: Includes Butternut Squash with Walnuts and Vanilla, Peruvian Roast Chicken with Red Potatoes, Lamb ... Pumpkin Spice Lattes...and hundreds more!

The Everything Gluten-Free Slow Cooker Cookbook: Includes Butternut Squash with Walnuts and Vanilla, Peruvian Roast Chicken with Red Potatoes, Lamb ... Pumpkin Spice Lattes...and hundreds more!
by Carrie S. Forbes (Author)


All you need to make simple, delicious, and naturally gluten-free mealsSlow cookers are lifesavers for busy cooks. But if you follow a gluten-free diet - due to celiac disease, gluten intolerance, wheat allergies, or simply for health reasons - slow cooking can be a challenge. That's because many recipes don't thicken properly without flour, noodles, or some other wheat-containing derivative. Enter: The Everything Gluten-Free Slow Cooker Cookbook.Inside, you'll find delicious gluten-free recipes such as:Pull-Apart Cinnamon Raisin BiscuitsBreakfast RisottoPineapple Teriyaki DrumsticksBacon Corn ChowderSpicy Vegetarian ChiliChicken Alfredo PastaSausage and Shrimp JambalayaCurried Coconut ChickenBarbecue Western RibsBlueberry CobblerRight-Side-Up Pineapple Cake Complete with an array of...

© 2016 BrightSurf.com