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Worldwide clinical trials for new technique for early detection of eye disease
October 12, 2004A unique new non-invasive technique for high resolution optical imaging of the eye is receiving global acclaim. The technique, pioneered by the University of Kent, is funded by the Toronto-based company, Ophthalmic Technology Inc (OTI). The University's Applied Optics Group is currently working with university hospitals in New York (USA), Osaka (Japan), Asahikawa (Japan), Amsterdam (Netherlands) and Milan (Italy) to carry out preliminary clinical trials. By combining two high-resolution imaging technologies, the new technique provides doctors with 3-D images of the retina, macula and the optic nerve. Such high resolution images provide clinicians with capabilities for early diagnosis and treatment of common ocular diseases such as glaucoma, diabetes and age-related macula degeneration. OTI is planning in the near future to extend the clinical research to other leading university medical centres in Japan, USA and Europe.
The Kent team, based in the School of Physical Sciences, is the only research group in the world carrying out this type of work. Co-ordinated by Professor Adrian Podoleanu, it operates out of two laboratories. One is in the UK at the University's Canterbury campus and the other is in the United States at the New York Medical College, where Adrian Podoleanu is a Visiting Professor. Other members of the team include Professor David Jackson, Dr John Rogers, a former Kent PhD student now the director of OCT Research at OTI and lecturer George Dobre.
Adrian Podoleanu explained: 'At Kent we created a very cost effective imaging system which simultaneously produces optical coherence tomography (OCT) and scanning laser ophthalmoscope (SLO) images. Its early potential was immediately realised by OTI, who commissioned the assembly of several prototypes to be tested in different clinics worldwide before embarking on commercial exploitation of the invention'.
The first clinic to test the new instrument was at the New York Eye and Ear Infirmary. Since the first installation, OTI, The Applied Optics group in Kent and the Retina Research Lab in New York work together to further improve and enhance the performance of the technology.
Dr Richard Rosen, Director of the Retinal Imaging Laboratory, was so impressed by the results that he and his researchers have been working closely with the team ever since and are currently involved with the clinical trials.
He said: 'The simultaneous presentation of images drawn from two technologies, developed by the Kent group has opened several exciting avenues in imaging the eye, giving us access to a world of minute details not possible to be visualised by the more conventional imaging technologies'.
The clinical investigators together with the Kent team have jointly published in international medical publications and presented at clinical and scientific conferences over 50 publications and presentations related to this research.
Kent, University of
The first clinic to test the new instrument was at the New York Eye and Ear Infirmary. Since the first installation, OTI, The Applied Optics group in Kent and the Retina Research Lab in New York work together to further improve and enhance the performance of the technology.
Dr Richard Rosen, Director of the Retinal Imaging Laboratory, was so impressed by the results that he and his researchers have been working closely with the team ever since and are currently involved with the clinical trials.
He said: 'The simultaneous presentation of images drawn from two technologies, developed by the Kent group has opened several exciting avenues in imaging the eye, giving us access to a world of minute details not possible to be visualised by the more conventional imaging technologies'.
The clinical investigators together with the Kent team have jointly published in international medical publications and presented at clinical and scientific conferences over 50 publications and presentations related to this research.
Kent, University of
Aging Current Events and Aging News RSSApproved lymphoma drug shows promise in early tests against bone cancer
A drug already approved for the treatment of lymphoma may also slow the growth of the most deadly bone cancer in children and teens, according to an early-stage study published online today in the International Journal of Cancer.
Researchers explore new ways to prevent spinal cord damage using a vitamin B3 precursor
Substances naturally produced by the human body may one day help prevent paralysis following a spinal cord injury, according to researchers at Weill Cornell Medical College. A recent $2.5 million grant from the New York State Spinal Cord Injury Research Board will fund their research investigating this possibility.
Estrogen therapy likely must be given soon after menopause to provide stroke protection
For estrogen replacement to provide stroke protection, it likely must be given soon after levels drop because of menopause or surgical removal of the ovaries, scientists report in the Journal of Neuroscience.
Expert Predicts Possible Shift in Senior Voting Bloc
The majority of people aged 65 and over cast ballots for John McCain in 2008, but older voters will not necessarily favor Republicans in future presidential elections, according to an article in the latest issue of The Gerontologist (Vol. 49, No. 5).
Reduction in glycotoxins from heat-processing of foods reduces risk of chronic disease
Researchers from Mount Sinai School of Medicine report that cutting back on the consumption of processed and fried foods, which are high in toxins called Advanced Glycation End products (AGEs), can reduce inflammation and actually help restore the body's natural defenses regardless of age or health status.
Study: depression can lead to inflated reports of physical symptoms
New research shows people who feel depressed tend to recall having more physical symptoms than they actually experienced. The study indicates that depression -- not neuroticism -- is the cause of such over-reporting.
Older Patients with Dementia at Increased Risk for Flu Mortality
An epidemiological study on pneumonia and influenza (P&I) in adults age 65 and over reports that patients with dementia are diagnosed with flu less frequently, have shorter hospital stays, and have a fifty percent higher rate of death than those without dementia.
URI research couple's method targets cancerous tumors
Two University of Rhode Island associate professors, biophysicists Yana Reshetnyak and Oleg Andreev, have discovered a technology that can detect cancerous tumors and deliver treatment to them without the harming the healthy cells surrounding them, thereby significantly reducing side effects.
Common weed could provide clues on aging and cancer
A common weed and human cancer cells could provide some very uncommon details about DNA structure and its relationship with telomeres and how they affect cellular aging and cancer, according to a team led by scientists from Texas A&M University and the University of Cincinnati (UC).
Changing behavior helps patients take medication as prescribed
Taking medication as the doctor prescribes is crucial to improving health. However, 26 to 59 percent of older adults do not adhere to instructions, according to a 2003 study published in Drugs and Aging.
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