Science Current Events | Science News | Brightsurf.com
 

Mayo Clinic: Add Bone Deterioration to Diabetes Complications

November 13, 2013
ROCHESTER, Minn. - The list of complications from type 2 diabetes is long: vascular and heart disease, eye problems, nerve damage, kidney disease, hearing problems and Alzheimer's disease. Physicians have long thought of osteoporosis as another outcome. Based on a Mayo Clinic study published in the Journal of Bone and Mineral Research, that's confirmed: You can definitely add skeletal problems to that list.

"This is the first demonstration - using direct measurement of bone strength in the body - of compromised bone material in patients with type 2 diabetes," says Sundeep Khosla, M.D. , Mayo Clinic endocrinologist and senior author of the study. "Clearly, the skeleton needs to be recognized as another important target of diabetes complications."

Previous studies in the field showed that patients with diabetes experienced fractures at levels of bone density above that of the regular population, hinting that something was different about the "quality" of their bone. The Mayo researchers validated that assumption in a clinical study of 60 postmenopausal women, 30 of whom had type 2 diabetes. Using a new tool (OsteoProbe®), the researchers performed micro indentation testing of the tibia (actually causing a microscopic crack) to measure bone material strength. Compared to the control group of women, aged 50 to 80, the group with type 2 diabetes had significantly lower bone material strength. There was no difference between the microarchitecture of the bone or bone density between the two groups. The study showed that diabetic women with lower bone material strength had also experienced higher levels of hyperglycemia over the previous 10 years, suggesting potential detrimental effects of poor glucose control on bone quality.

The resounding message: Conventional measurements underestimated the risk of fracture among patients with type 2 diabetes and loss of bone material strength, or bone quality, is a clear, downstream consequence of the disease. The new technology may help in studying other conditions where fractures occur at higher than expected bone density, says co-author and rheumatologist Shreyasee Amin, M.D. She says this will be especially relevant to many forms of autoimmune arthritis where glucocorticoids are used, such as in rheumatoid arthritis. The team says more research needs to be done, as this was a small study in a limited population. The studies were supported by the National Institutes of Health, including funding from Mayo's Clinical and Translational Science Award.

Other collaborators on the study include first author Joshua Farr, Ph.D.; Matthew Drake, M.D., Ph.D.; L. Joseph Melton III, M.D. and Louise McCready, all of Mayo Clinic. The authors have no financial interest in the OsteoProbe® technology.

Mayo Clinic


Related Diabetes Current Events and Diabetes News Articles


Applying new cholesterol guidelines to a patient population reduces heart attacks, strokes, study finds
A study from UT Southwestern researchers found that recently introduced cholesterol guidelines would significantly reduce new cardiovascular events, when compared to treatment based on previous cholesterol guidelines.

Proteins critical to wound healing identified
Mice missing two important proteins of the vascular system develop normally and appear healthy in adulthood, as long as they don't become injured. If they do, their wounds don't heal properly, a new study shows.

Blood pressure medication does not cause more falls
It's time to question the common belief that patients receiving intensive blood pressure treatment are prone to falling and breaking bones.

Do gut bacteria rule our minds?
It sounds like science fiction, but it seems that bacteria within us - which outnumber our own cells about 100-fold - may very well be affecting both our cravings and moods to get us to eat what they want, and often are driving us toward obesity.

Poor health literacy poses risks for pacemaker and defibrillator patients
Patients who rely on pacemakers and defibrillators to maintain a normal heart rhythm run the risk of serious health complications if they don't fully understand how the devices work and what to do when they experience an irregular heartbeat.

Message to parents: Babies don't 'start from scratch'
There's now overwhelming evidence that a child's future health is influenced by more than just their parents' genetic material, and that children born of unhealthy parents will already be pre-programmed for greater risk of poor health, according to University of Adelaide researchers.

A husband's declining health could put Taiwanese women at risk for health issues
The death of a spouse undoubtedly brings with it stress, anxiety and uncertainty. Now, a report by Princeton University's Woodrow Wilson School of Public and International Affairs quantifies this stress, showing how a husband's declining health could put Taiwanese women at risk for health issues.

Severity of sleep apnea impacts risk of resistant high blood pressure
A new study shows a strong association between severe, untreated obstructive sleep apnea and the risk of elevated blood pressure despite the use of high blood pressure medications.

Single enzyme is necessary for development of diabetes
An enzyme called 12-LO promotes the obesity-induced oxidative stress in the pancreatic cells that leads to pre-diabetes, and diabetes.

Scientists make major breakthrough in understanding leukemia
Scientists from Queen Mary University of London (QMUL) have discovered mutations in genes that lead to childhood leukaemia of the acute lymphoblastic type - the most common childhood cancer in the world.
More Diabetes Current Events and Diabetes News Articles

The End of Diabetes: The Eat to Live Plan to Prevent and Reverse Diabetes

The End of Diabetes: The Eat to Live Plan to Prevent and Reverse Diabetes
by Joel Fuhrman (Author)


The New York Times bestselling author of Eat to Live and Super Immunity and one of the country’s leading experts on preventive medicine offers a scientifically proven, practical program to prevent and reverse diabetes—without drugs.At last, a breakthrough program to combat the rising diabetes epidemic and help millions of diabetics, as well as those suffering with high blood pressure and heart disease. Joel Fuhrman, M.D. Research director of the Nutritional Research Foundation, shows you how to live a long, healthy, and happy life—disease free. He offers a complete health transformation, starting with a diet with a high nutrient-per-calorie ratio that can be adapted for individual needs.Dr. Fuhrman makes clear that we don’t have to “control” diabetes. Patients can choose to...

The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed

The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed
by Gretchen Becker (Author), Allison B. Goldfine (Foreword)


After Gretchen Becker was diagnosed with type 2 diabetes in 1996, she educated herself on every aspect of this chronic condition — by reading medical and scientific books and journals, talking with doctors and listening to her own body. In 2001, she marshaled everything she had learned as a "patient-expert" into the first edition of this book, which she has now completely updated and revised. The First Year®—Type 2 Diabetes uniquely guides you step-by-step through your first year with diabetes, walking you through everything you need to learn and do each day of your first week after diagnosis, each subsequent week of the first month, and each subsequent month of the crucial first year. In clear, concise, accessible language, Becker covers a wide range of practical, medical, and...

Mayo Clinic The Essential Diabetes Book

Mayo Clinic The Essential Diabetes Book
by Mayo Clinic (Author)


More people than ever before have diabetes. The disease affects an estimated 21 million adults and children in the US and many people with the disease don't have it under control. Unlike years ago, you have a good chance of living an active and healthy life with diabetes - provided you work with your health-care team to take the necessary steps to control your blood sugar. This title covers: the pre-diabetes stage - taking charge to prevent diabetes; types of diabetes; symptoms and risk factors; treatments and strategies for managing your blood sugar; avoiding serious complications; advances in insulin delivery and new medications; and, recipes

The Official Pocket Guide to Diabetic Exchanges: Choose Your Foods

The Official Pocket Guide to Diabetic Exchanges: Choose Your Foods
by ADA American Diabetes Association (Author)


Completely updated to match the newest edition of Choose Your Foods: Exchange Lists for Diabetes Meal Planning, this pocket-sized bestseller is now better and more complete than ever.

Every day and at every meal, millions of people use the exchange list system to help them plan their meal, choose the healthiest foods, and estimate the right portions. By grouping similar foods into exchangeable portion sizes, people with diabetes can instantly create entire meals, specifically designed to help them control their blood glucose and lose weight. This proven system is the most popular approach to diabetes meal planning and has been used by dietitians, diabetes educators, and millions of people with diabetes for over 40 years.

This portable, pocket-sized version of the Choose Your...

Diabetes For Dummies

Diabetes For Dummies
by Alan L. Rubin (Author)


The straight facts on treating diabetes successfullyWith diabetes now considered pandemic throughout the world, there have been an enormous advances in the field since the last edition of Diabetes For Dummies. Now significantly revised and updated, it includes the latest information on medications and monitoring equipment, updated diet and exercise plans, new findings about treating diabetes in the young and elderly, new ways to diagnose and treat long- and short-term complications, and more.Want to know how to manage diabetes? Trusted diabetes expert Dr. Alan Rubin gives you reassuring, authoritative guidance on putting together a state-of-the-art treatment program to treat diabetes successfully and live a full life. You'll learn about all the advances in monitoring glucose, the latest...

Diabetes Diet: The 101 Best Diabetic Foods

Diabetes Diet: The 101 Best Diabetic Foods
by Health Research Staff (Author)


Stuck in a meal rut and tired of the same old foods?

If you?re someone who is dealing with diabetes, there?s no question that you must be paying attention to what you eat each day. The foods you put into your body are going to have a very strong influence on not only how well you feel, but on how well you handle this condition altogether.

By making smart food choices, you can maintain control over your diabetes and live the lifestyle that you want to lead.

The following 101 foods will do just that. We?ve selected the top picks that you should include in your diet plan regularly so you no longer have to wonder what to eat.

This list is meant to encourage you to broaden your eating choices. This prevents the boredom that many experience by getting stuck on...

Diabetes: The Ultimate Diabetes Guide - The Best Tips and Advice You Need To Treat Diabetes Successfully!

Diabetes: The Ultimate Diabetes Guide - The Best Tips and Advice You Need To Treat Diabetes Successfully!


Learn the Best Advice on Diabetes Today!
Today only, get this Kindle e-book for only $2.99, regularly priced at $8.49. Read on your PC, Mac, smart phone, tablet or Kindle device.

This book contains proven steps and strategies on how to cope with Diabetes.

Diabetes Mellitus or Diabetes is a condition where a person has high levels of sugar in the blood. This can be caused by the pancreas being unable to produce enough insulin, or the cells of the body cannot do its job in transferring the sugar into it.

There are lots of people who are affected by Diabetes and there have been a lot of clinical studies done in order to help these people. This condition is very serious, and if left unattended, can lead to worse complications, and eventually,...

Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes without Drugs

Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes without Drugs
by Neal D. Barnard (Author)


Until Dr. Barnard’s scientific breakthrough, most health professionals believed that once you developed diabetes, you were stuck with it—and could anticipate one complication after another, from worsening eyesight and nerve symptoms to heart and kidney problems. But as this groundbreaking work reveals, this simply is not true. In a series of studies—the most recent funded by the National Institutes of Health—Dr. Barnard has shown that it is possible to repair insulin function and reverse type 2 diabetes. By following his scientifically proven, life-changing program, diabetics can control blood sugar three times more effectively than with the standard diet; and cut back on and in some cases eliminate medications while reducing the risk of diabetes complications. "The long overdue...

The American Diabetes Association Diabetes Comfort Food Cookbook

The American Diabetes Association Diabetes Comfort Food Cookbook
by Robyn Webb (Author)


While fancy and sophisticated foods continue to grow in popularity, ask most people what their favorite foods are and the answer will invariably be classic comfort foods: lasagna, meat loaf, mac and cheese, and cake. Unfortunately, most people think that having diabetes means the days of enjoying these hearty classics are long gone, and that their favorite foods are a thing of the past. Author Robyn Webb shows that healthy eating doesn't have to mean giving up on favorite foods! Diabetes can be overwhelming, but it doesn't mean reinventing the wheel when it comes to cooking. Just a tweak here and there and familiar foods can remain favorites, guilt-free, and enjoyed every day.

The American Diabetes Association Diabetes Comfort Food Cookbook creates a “go-to” collection of...

What Do I Eat Now?: A Step-by-Step Guide to Eating Right with Type 2 Diabetes

What Do I Eat Now?: A Step-by-Step Guide to Eating Right with Type 2 Diabetes
by Patti Geil (Author), Tami A. Ross (Author)


The DIY approach to a diabetes diet!
What Do I Eat Now? is the single best resource for people with diabetes to learn how to eat right and eat healthy with diabetes. Each chapter explains a vital concept of diabetes nutrition in easy-to-understand language. “Tell Me What to Eat” meal plans and recipes at the end of each chapter get readers started on a lifetime of healthy eating. Don’t waste time trying to figure everything out from scratch when What Do I Eat Now? gives readers a step-by-step plan for understanding how to eat right. Learn as you go by cooking healthy, nutritious, and flavorful diabetic meals!

© 2014 BrightSurf.com