Science Current Events | Science News | Brightsurf.com
 

Mayo Clinic: Add Bone Deterioration to Diabetes Complications

November 13, 2013
ROCHESTER, Minn. - The list of complications from type 2 diabetes is long: vascular and heart disease, eye problems, nerve damage, kidney disease, hearing problems and Alzheimer's disease. Physicians have long thought of osteoporosis as another outcome. Based on a Mayo Clinic study published in the Journal of Bone and Mineral Research, that's confirmed: You can definitely add skeletal problems to that list.

"This is the first demonstration - using direct measurement of bone strength in the body - of compromised bone material in patients with type 2 diabetes," says Sundeep Khosla, M.D. , Mayo Clinic endocrinologist and senior author of the study. "Clearly, the skeleton needs to be recognized as another important target of diabetes complications."

Previous studies in the field showed that patients with diabetes experienced fractures at levels of bone density above that of the regular population, hinting that something was different about the "quality" of their bone. The Mayo researchers validated that assumption in a clinical study of 60 postmenopausal women, 30 of whom had type 2 diabetes. Using a new tool (OsteoProbe®), the researchers performed micro indentation testing of the tibia (actually causing a microscopic crack) to measure bone material strength. Compared to the control group of women, aged 50 to 80, the group with type 2 diabetes had significantly lower bone material strength. There was no difference between the microarchitecture of the bone or bone density between the two groups. The study showed that diabetic women with lower bone material strength had also experienced higher levels of hyperglycemia over the previous 10 years, suggesting potential detrimental effects of poor glucose control on bone quality.

The resounding message: Conventional measurements underestimated the risk of fracture among patients with type 2 diabetes and loss of bone material strength, or bone quality, is a clear, downstream consequence of the disease. The new technology may help in studying other conditions where fractures occur at higher than expected bone density, says co-author and rheumatologist Shreyasee Amin, M.D. She says this will be especially relevant to many forms of autoimmune arthritis where glucocorticoids are used, such as in rheumatoid arthritis. The team says more research needs to be done, as this was a small study in a limited population. The studies were supported by the National Institutes of Health, including funding from Mayo's Clinical and Translational Science Award.

Other collaborators on the study include first author Joshua Farr, Ph.D.; Matthew Drake, M.D., Ph.D.; L. Joseph Melton III, M.D. and Louise McCready, all of Mayo Clinic. The authors have no financial interest in the OsteoProbe® technology.

Mayo Clinic


Related Diabetes Current Events and Diabetes News Articles


Preventing metabolic disease may start in the womb... of your grandmother
No one wants to have child who is born underweight, but for numerous reasons, this may be unavoidable.

Genetically speaking, mammals are more like their fathers
You might resemble or act more like your mother, but a novel research study from UNC School of Medicine researchers reveals that mammals are genetically more like their dads.

Joslin scientists find direct link between insulin resistance and behavioral disorders
People with diabetes are more prone to anxiety and depression than those with other chronic diseases that require similar levels of management. The reasons for this aren't well understood, but Joslin Diabetes Center researchers have discovered one potential explanation.

Study shows strong link between adolescent obesity and high blood pressure
A recent study published in the American Journal of Hypertension has found that body mass index (BMI) in healthy adolescents has a statistically significant association with both systolic blood pressures (SBP) and diastolic blood pressures (DBP), and highlights the significance of the global trend of rapidly increasing adolescent obesity.

Gold standard management of the diabetic cat
The International Society of Feline Medicine (ISFM), the veterinary division of International Cat Care, has convened an expert panel of veterinary clinicians and academics to produce practical guidance to help veterinary teams deliver optimal management for the increasing numbers of diabetic cats that are presenting to practices.

Neurons controlling appetite made from skin cells
Researchers have for the first time successfully converted adult human skin cells into neurons of the type that regulate appetite, providing a patient-specific model for studying the neurophysiology of weight control and testing new therapies for obesity.

Cesarean section rates in Portugal decline by 10 percent
A new study reports a significant decline in the rate of cesarean section (C-section) births in Portugal. Findings published in Acta Obstetricia et Gynecologica Scandinavica, a journal of the Nordic Federation of Societies of Obstetrics and Gynecology, indicate a 10% reduction in overall C-section rates between 2009 and 2014, with a 14% reduction in state-hospitals during the same time period.

Treadmill performance predicts mortality
Analyzing data from 58,000 heart stress tests, Johns Hopkins cardiologists report they have developed a formula that estimates one's risk of dying over a decade based on a person's ability to exercise on a treadmill at an increasing speed and incline.

With kids' antipsychotic treatment on the rise, study looks at prescriber decision-making
More kids nationwide are taking medications designed to treat such mental illnesses as schizophrenia and bipolar disorder, and pediatricians and psychiatrists at the University of Vermont want to know why.

Statin use associated with reduced risk of liver cancer among those in the UK
In a nested-case control study of individuals living in the UK, a part of the world with a relatively low incidence of liver cancer, statin use is associated with a decreased risk of liver cancer.
More Diabetes Current Events and Diabetes News Articles

The End of Diabetes: The Eat to Live Plan to Prevent and Reverse Diabetes

The End of Diabetes: The Eat to Live Plan to Prevent and Reverse Diabetes
by Joel Fuhrman (Author)


The New York Times bestselling author of Eat to Live and Super Immunity and one of the country’s leading experts on preventive medicine offers a scientifically proven, practical program to prevent and reverse diabetes—without drugs.At last, a breakthrough program to combat the rising diabetes epidemic and help millions of diabetics, as well as those suffering with high blood pressure and heart disease. Joel Fuhrman, M.D. Research director of the Nutritional Research Foundation, shows you how to live a long, healthy, and happy life—disease free. He offers a complete health transformation, starting with a diet with a high nutrient-per-calorie ratio that can be adapted for individual needs.Dr. Fuhrman makes clear that we don’t have to “control” diabetes. Patients can choose to...

Mayo Clinic The Essential Diabetes Book

Mayo Clinic The Essential Diabetes Book
by Mayo Clinic (Author)


More people than ever before have diabetes. The disease affects an estimated 21 million adults and children in the US and many people with the disease don't have it under control. Unlike years ago, you have a good chance of living an active and healthy life with diabetes - provided you work with your health-care team to take the necessary steps to control your blood sugar. This title covers: the pre-diabetes stage - taking charge to prevent diabetes; types of diabetes; symptoms and risk factors; treatments and strategies for managing your blood sugar; avoiding serious complications; advances in insulin delivery and new medications; and, recipes

Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes without Drugs

Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes without Drugs
by Neal D. Barnard (Author)


Until Dr. Barnard’s scientific breakthrough, most health professionals believed that once you developed diabetes, you were stuck with it—and could anticipate one complication after another, from worsening eyesight and nerve symptoms to heart and kidney problems. But as this groundbreaking work reveals, this simply is not true. In a series of studies—the most recent funded by the National Institutes of Health—Dr. Barnard has shown that it is possible to repair insulin function and reverse type 2 diabetes. By following his scientifically proven, life-changing program, diabetics can control blood sugar three times more effectively than with the standard diet; and cut back on and in some cases eliminate medications while reducing the risk of diabetes complications. "The long overdue...

Diabetes: The Ultimate Diabetes Guide - The Best Tips and Advice You Need To Treat Diabetes Successfully!

Diabetes: The Ultimate Diabetes Guide - The Best Tips and Advice You Need To Treat Diabetes Successfully!


Learn the Best Advice on Diabetes Today!
Today only, get this Kindle e-book for only $2.99, regularly priced at $8.49. Read on your PC, Mac, smart phone, tablet or Kindle device.

This book contains proven steps and strategies on how to cope with Diabetes.

Diabetes Mellitus or Diabetes is a condition where a person has high levels of sugar in the blood. This can be caused by the pancreas being unable to produce enough insulin, or the cells of the body cannot do its job in transferring the sugar into it.

There are lots of people who are affected by Diabetes and there have been a lot of clinical studies done in order to help these people. This condition is very serious, and if left unattended, can lead to worse complications, and eventually,...

Diabetes For Dummies

Diabetes For Dummies
by Alan L. Rubin (Author)


The straight facts on treating diabetes successfully With diabetes now considered pandemic throughout the world, there have been an enormous advances in the field since the last edition of Diabetes For Dummies. Now significantly revised and updated, it includes the latest information on medications and monitoring equipment, updated diet and exercise plans, new findings about treating diabetes in the young and elderly, new ways to diagnose and treat long- and short-term complications, and more. Want to know how to manage diabetes? Trusted diabetes expert Dr. Alan Rubin gives you reassuring, authoritative guidance on putting together a state-of-the-art treatment program to treat diabetes successfully and live a full life. You'll learn about all the advances in monitoring glucose, the...

The Official Pocket Guide to Diabetic Exchanges: Choose Your Foods

The Official Pocket Guide to Diabetic Exchanges: Choose Your Foods
by American Diabetes Association (Author)


Completely updated to match the newest edition of Choose Your Foods: Exchange Lists for Diabetes Meal Planning, this pocket-sized bestseller is now better and more complete than ever.

Every day and at every meal, millions of people use the exchange list system to help them plan their meal, choose the healthiest foods, and estimate the right portions. By grouping similar foods into exchangeable portion sizes, people with diabetes can instantly create entire meals, specifically designed to help them control their blood glucose and lose weight. This proven system is the most popular approach to diabetes meal planning and has been used by dietitians, diabetes educators, and millions of people with diabetes for over 40 years.

This portable, pocket-sized version of the Choose Your...

What Do I Eat Now?: A Step-by-Step Guide to Eating Right with Type 2 Diabetes

What Do I Eat Now?: A Step-by-Step Guide to Eating Right with Type 2 Diabetes
by Patti Geil (Author), Tami A. Ross (Author)


The DIY approach to a diabetes diet!
What Do I Eat Now? is the single best resource for people with diabetes to learn how to eat right and eat healthy with diabetes. Each chapter explains a vital concept of diabetes nutrition in easy-to-understand language. “Tell Me What to Eat” meal plans and recipes at the end of each chapter get readers started on a lifetime of healthy eating. Don’t waste time trying to figure everything out from scratch when What Do I Eat Now? gives readers a step-by-step plan for understanding how to eat right. Learn as you go by cooking healthy, nutritious, and flavorful diabetic meals!

The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed

The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed
by Gretchen Becker (Author), Allison B. Goldfine (Foreword)


After Gretchen Becker was diagnosed with type 2 diabetes in 1996, she educated herself on every aspect of this chronic condition — by reading medical and scientific books and journals, talking with doctors and listening to her own body. In 2001, she marshaled everything she had learned as a "patient-expert" into the first edition of this book, which she has now completely updated and revised. The First Year®—Type 2 Diabetes uniquely guides you step-by-step through your first year with diabetes, walking you through everything you need to learn and do each day of your first week after diagnosis, each subsequent week of the first month, and each subsequent month of the crucial first year. In clear, concise, accessible language, Becker covers a wide range of practical, medical, and...

The American Diabetes Association Diabetes Comfort Food Cookbook

The American Diabetes Association Diabetes Comfort Food Cookbook
by Robyn Webb (Author)


While fancy and sophisticated foods continue to grow in popularity, ask most people what their favorite foods are and the answer will invariably be classic comfort foods: lasagna, meat loaf, mac and cheese, and cake. Unfortunately, most people think that having diabetes means the days of enjoying these hearty classics are long gone, and that their favorite foods are a thing of the past. Author Robyn Webb shows that healthy eating doesn't have to mean giving up on favorite foods! Diabetes can be overwhelming, but it doesn't mean reinventing the wheel when it comes to cooking. Just a tweak here and there and familiar foods can remain favorites, guilt-free, and enjoyed every day.

The American Diabetes Association Diabetes Comfort Food Cookbook creates a “go-to” collection of...

The Mayo Clinic Diabetes Diet: The #1 New York Bestseller adapted for people with diabetes

The Mayo Clinic Diabetes Diet: The #1 New York Bestseller adapted for people with diabetes
by the weight-loss experts at Mayo Clinic (Author)


The #1 New York Times bestseller adapted for people with diabetes, now in paperback—with 16 brand-new pages, full of menus designed to kick-start your weight loss and control your blood sugar. From Mayo Clinic, a leading authority in health and nutrition, comes The Mayo Clinic Diabetes Diet, adapted for people with pre-diabetes and type 2 diabetes from the #1 New York Times bestseller, The Mayo Clinic Diet. This reliable plan is what you need to lose weight to help you control your blood sugar. The medical specialists at Mayo Clinic have created The Mayo Clinic Diabetes Diet as a two-phase plan—Lose It! and Live It! The Diet helps at-risk people prevent and control diabetes by losing weight quickly and safely, and then maintaining that weight loss.  

The Lose It! phase is a...

© 2015 BrightSurf.com