Science Current Events | Science News | Brightsurf.com
 

Mayo Clinic: Add Bone Deterioration to Diabetes Complications

November 13, 2013
ROCHESTER, Minn. - The list of complications from type 2 diabetes is long: vascular and heart disease, eye problems, nerve damage, kidney disease, hearing problems and Alzheimer's disease. Physicians have long thought of osteoporosis as another outcome. Based on a Mayo Clinic study published in the Journal of Bone and Mineral Research, that's confirmed: You can definitely add skeletal problems to that list.

"This is the first demonstration - using direct measurement of bone strength in the body - of compromised bone material in patients with type 2 diabetes," says Sundeep Khosla, M.D. , Mayo Clinic endocrinologist and senior author of the study. "Clearly, the skeleton needs to be recognized as another important target of diabetes complications."

Previous studies in the field showed that patients with diabetes experienced fractures at levels of bone density above that of the regular population, hinting that something was different about the "quality" of their bone. The Mayo researchers validated that assumption in a clinical study of 60 postmenopausal women, 30 of whom had type 2 diabetes. Using a new tool (OsteoProbe®), the researchers performed micro indentation testing of the tibia (actually causing a microscopic crack) to measure bone material strength. Compared to the control group of women, aged 50 to 80, the group with type 2 diabetes had significantly lower bone material strength. There was no difference between the microarchitecture of the bone or bone density between the two groups. The study showed that diabetic women with lower bone material strength had also experienced higher levels of hyperglycemia over the previous 10 years, suggesting potential detrimental effects of poor glucose control on bone quality.

The resounding message: Conventional measurements underestimated the risk of fracture among patients with type 2 diabetes and loss of bone material strength, or bone quality, is a clear, downstream consequence of the disease. The new technology may help in studying other conditions where fractures occur at higher than expected bone density, says co-author and rheumatologist Shreyasee Amin, M.D. She says this will be especially relevant to many forms of autoimmune arthritis where glucocorticoids are used, such as in rheumatoid arthritis. The team says more research needs to be done, as this was a small study in a limited population. The studies were supported by the National Institutes of Health, including funding from Mayo's Clinical and Translational Science Award.

Other collaborators on the study include first author Joshua Farr, Ph.D.; Matthew Drake, M.D., Ph.D.; L. Joseph Melton III, M.D. and Louise McCready, all of Mayo Clinic. The authors have no financial interest in the OsteoProbe® technology.

Mayo Clinic


Related Diabetes Current Events and Diabetes News Articles


A scientific breakthrough helps explain how DNA is organized in our cells
A team of researchers at the IRCM led by François Robert, PhD, uncovered a critical role for two proteins in chromatin structure.

Study adds to evidence that increasing dietary fiber reduces the risk of developing diabetes
New research published today in Diabetologia (the journal of the European Association for the Study of Diabetes) indicates that consuming greater quantities of dietary fibre reduces the risk of developing type 2 diabetes.

Study identifies possible role for carbon monoxide in treating hemorrhagic stroke
Carbon monoxide is known by many as a poisonous gas that causes brain injury and other neurological symptoms, including memory loss and confusion.

Scientists identify origins of process that is key to diabetes
Oklahoma Medical Research Foundation scientists have pinpointed a cell that begins the process of scarring in fatty tissue.

Penn study links better 'good cholesterol' function with lower risk of later heart disease
HDL is the 'good cholesterol' that helps remove fat from artery walls, reversing the process that leads to heart disease.

Study suggests new way of preventing diabetes-associated blindness
Reporting on their study with lab-grown human cells, researchers at The Johns Hopkins University and the University of Maryland say that blocking a second blood vessel growth protein, along with one that is already well-known, could offer a new way to treat and prevent a blinding eye disease caused by diabetes.

Complex signaling between blood and stem cells controls regeneration in fly gut
Having a healthy gut may well depend on maintaining a complex signaling dance between immune cells and the stem cells that line the intestine.

Road traffic noise linked to heightened risk of mid-riff bulge
Road traffic noise is linked to a heightened risk of developing a mid-riff bulge, indicates research published online in Occupational & Environmental Medicine.

Obese male mice produce more disease-promoting immune cells than females
Obesity may be tougher on male immune systems than females, a new study in mice at the University of Michigan Medical School suggests.

ER doctors stress need for good communications with police
A good working relationship with police is essential for the smooth operation of a busy Emergency Department. Police are in and out of EDs regularly, supporting EMS, transporting patients and helping to provide a safe environment for hospital staff.
More Diabetes Current Events and Diabetes News Articles

The End of Diabetes: The Eat to Live Plan to Prevent and Reverse Diabetes

The End of Diabetes: The Eat to Live Plan to Prevent and Reverse Diabetes
by Joel Fuhrman (Author)


The New York Times bestselling author of Eat to Live and Super Immunity and one of the country’s leading experts on preventive medicine offers a scientifically proven, practical program to prevent and reverse diabetes—without drugs.At last, a breakthrough program to combat the rising diabetes epidemic and help millions of diabetics, as well as those suffering with high blood pressure and heart disease. Joel Fuhrman, M.D. Research director of the Nutritional Research Foundation, shows you how to live a long, healthy, and happy life—disease free. He offers a complete health transformation, starting with a diet with a high nutrient-per-calorie ratio that can be adapted for individual needs.Dr. Fuhrman makes clear that we don’t have to “control” diabetes. Patients can choose to...

Diabetic Living Diabetes Meals by the Plate: 90 Low-Carb Meals to Mix & Match

Diabetic Living Diabetes Meals by the Plate: 90 Low-Carb Meals to Mix & Match
by Diabetic Living Editors (Author)


An easy, graphic guide to planning delicious, diabetes-friendly meals   This innovative, graphic cookbook offers the easiest and most flavorful way to build complete meals that are diabetes-friendly and delicious. Sidestepping complex programs that turn meal-planning into work, the 90 complete meals in Diabetes Meals by the Plate follow the Plate Method—a simple approach to eating the right foods in proper amounts by filling your plate with one half nonstarchy vegetables, one quarter protein, and one quarter starch. A clever photo style showing every meal in its three components makes it easy to enjoy perfectly portioned plates of Balsamic Roasted Chicken and Vegetables with Garlic Toast, or Horseradish BBQ-Topped Mini Meat Loaves with Chopped Romaine Salad. All meals are 500 calories...

Diabetes For Dummies

Diabetes For Dummies
by Alan L. Rubin (Author)


The straight facts on treating diabetes successfully With diabetes now considered pandemic throughout the world, there have been an enormous advances in the field since the last edition of Diabetes For Dummies. Now significantly revised and updated, it includes the latest information on medications and monitoring equipment, updated diet and exercise plans, new findings about treating diabetes in the young and elderly, new ways to diagnose and treat long- and short-term complications, and more. Want to know how to manage diabetes? Trusted diabetes expert Dr. Alan Rubin gives you reassuring, authoritative guidance on putting together a state-of-the-art treatment program to treat diabetes successfully and live a full life. You'll learn about all the advances in monitoring glucose, the...

Mayo Clinic The Essential Diabetes Book

Mayo Clinic The Essential Diabetes Book
by Mayo Clinic (Author)


More people than ever before have diabetes. The disease affects an estimated 21 million adults and children in the US and many people with the disease don't have it under control. Unlike years ago, you have a good chance of living an active and healthy life with diabetes - provided you work with your health-care team to take the necessary steps to control your blood sugar. This title covers: the pre-diabetes stage - taking charge to prevent diabetes; types of diabetes; symptoms and risk factors; treatments and strategies for managing your blood sugar; avoiding serious complications; advances in insulin delivery and new medications; and, recipes

The Official Pocket Guide to Diabetic Exchanges: Choose Your Foods

The Official Pocket Guide to Diabetic Exchanges: Choose Your Foods
by American Diabetes Association (Author)


Completely updated to match the newest edition of Choose Your Foods: Exchange Lists for Diabetes Meal Planning, this pocket-sized bestseller is now better and more complete than ever.

Every day and at every meal, millions of people use the exchange list system to help them plan their meal, choose the healthiest foods, and estimate the right portions. By grouping similar foods into exchangeable portion sizes, people with diabetes can instantly create entire meals, specifically designed to help them control their blood glucose and lose weight. This proven system is the most popular approach to diabetes meal planning and has been used by dietitians, diabetes educators, and millions of people with diabetes for over 40 years.

This portable, pocket-sized version of the Choose Your...

Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes without Drugs

Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes without Drugs
by Neal D. Barnard (Author)


Until Dr. Barnard’s scientific breakthrough, most health professionals believed that once you developed diabetes, you were stuck with it—and could anticipate one complication after another, from worsening eyesight and nerve symptoms to heart and kidney problems. But as this groundbreaking work reveals, this simply is not true. In a series of studies—the most recent funded by the National Institutes of Health—Dr. Barnard has shown that it is possible to repair insulin function and reverse type 2 diabetes. By following his scientifically proven, life-changing program, diabetics can control blood sugar three times more effectively than with the standard diet; and cut back on and in some cases eliminate medications while reducing the risk of diabetes complications. "The long overdue...

The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed

The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed
by Gretchen Becker (Author), Allison B. Goldfine (Foreword)


After Gretchen Becker was diagnosed with type 2 diabetes in 1996, she educated herself on every aspect of this chronic condition — by reading medical and scientific books and journals, talking with doctors and listening to her own body. In 2001, she marshaled everything she had learned as a "patient-expert" into the first edition of this book, which she has now completely updated and revised. The First Year®—Type 2 Diabetes uniquely guides you step-by-step through your first year with diabetes, walking you through everything you need to learn and do each day of your first week after diagnosis, each subsequent week of the first month, and each subsequent month of the crucial first year. In clear, concise, accessible language, Becker covers a wide range of practical, medical, and...

What Do I Eat Now?: A Step-by-Step Guide to Eating Right with Type 2 Diabetes

What Do I Eat Now?: A Step-by-Step Guide to Eating Right with Type 2 Diabetes
by Patti Geil (Author), Tami A. Ross (Author)


The DIY approach to a diabetes diet!
What Do I Eat Now? is the single best resource for people with diabetes to learn how to eat right and eat healthy with diabetes. Each chapter explains a vital concept of diabetes nutrition in easy-to-understand language. “Tell Me What to Eat” meal plans and recipes at the end of each chapter get readers started on a lifetime of healthy eating. Don’t waste time trying to figure everything out from scratch when What Do I Eat Now? gives readers a step-by-step plan for understanding how to eat right. Learn as you go by cooking healthy, nutritious, and flavorful diabetic meals!

DIABETES: The Ultimate Diabetes Guide - The Best Tips and Advice You Need To Treat Diabetes Successfully!: DIABETES, Diabetes Diet

DIABETES: The Ultimate Diabetes Guide - The Best Tips and Advice You Need To Treat Diabetes Successfully!: DIABETES, Diabetes Diet


DIABETES
Learn the Best Advice on Diabetes Today!

"The Ultimate Diabetes Guide - The Best Tips and Advice You Need To Treat Diabetes Successfully!" contains proven steps and strategies on how to cope with Diabetes.

Diabetes Mellitus or Diabetes is a condition where a person has high levels of sugar in the blood. This can be caused by the pancreas being unable to produce enough insulin, or the cells of the body cannot do its job in transferring the sugar into it.

There are lots of people who are affected by Diabetes and there have been a lot of clinical studies done in order to help these people. This condition is very serious, and if left unattended, can lead to worse complications, and eventually, death. It is important for a person to...

American Diabetes Association Complete Guide to Diabetes: The Ultimate Home Reference from the Diabetes Experts (American Diabetes Association Comlete Guide to Diabetes)

American Diabetes Association Complete Guide to Diabetes: The Ultimate Home Reference from the Diabetes Experts (American Diabetes Association Comlete Guide to Diabetes)
by American Diabetes Association (Author)


The American Diabetes Association—the nation's leading health organization supporting diabetes research, information, and advocacy—has completely revised this comprehensive home reference to provide all the information a person needs to live an active, healthy life with diabetes. Now in its fifth edition, this extensive resource contains information on the best self-care techniques and the latest medical advances. For people with diabetes, this extraordinary guide will answer any question. Topics include the latest on self-care for type 1, type 2, and gestational diabetes; new types of insulin and medications; strategies for avoiding diabetes complications; expanded sections on meal planning and nutrition; and tips on working with the health care system and insurance...

© 2015 BrightSurf.com