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'Biggest ever' study of its kind may advance the treatment, diagnosis and prevention of Schizophrenia
August 12, 2004Scientists at the Babraham Institute have made significant advances in understanding schizophrenia. Schizophrenia is a mental illness which has been estimated to affect over 1% of the population and costs the NHS over £2.5 billion per year. Babraham scientists have pinpointed a breakdown in mitochondria - the power stations of the cell - as a key factor.
The discovery, described in an article published in Molecular Psychiatry, was made by a team of scientists working in Dr Sabine Bahn's research group at the Babraham Institute, Cambridge. The large-scale, multi-disciplinary approach has identified differences in the expression of genes related to energy production between schizophrenia patients and unaffected people.
The team studied tissue from over 100 brains and screened over 22,000 genes. Dr Bahn comments: "This study is the most extensive study of its kind so far, and we believe its multi-tier, complementary approach has provided surprising and convincing data. We hope that our findings will lead to advances in treatment, diagnosis and hopefully prevention of schizophrenia and related illnesses."
Babraham Institute, The
Babraham Institute, The
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Faulty 'wiring' in the brain triggers onset of schizophrenia
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General anesthetics lead to learning disabilities in animal models
Studies by researchers at Wake Forest University School of Medicine have shown that blocking the NMDA receptor in immature rats leads to profound, rapid brain injury and disruption of auditory function as the animals mature.
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Schizophrenia Revealed: From Neurons to Social Interactions by Michael Foster Green (Author) A modern view of schizophrenia based on neuroscience that goes far beyond the symptoms of the illness. "Green has lifted the bar in this realm of explanatory neuroscience-based psychiatry. If you wish to read an enjoyable and instructive primer on what we know about schizophrenia at the beginning of the 21st century, you could do no better than to choose Schizophrenia Revealed." —New England Journal of Medicine |
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The Quiet Room: A Journey Out of the Torment of Madness by Lori Schiller (Author), Amanda Bennett (Author) Schiller's gripping, heart-rending and ultimately triumphant story of her journey into madness and back to reality is told through the voices of Lori and her family, friends and doctor, and captures a rare, astoundingly vivid view into the inner life of a schizophrenic. "A stunning story of courage, persistence, and hope."--Publishers Weekly. |
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Surviving Schizophrenia: A Manual for Families, Patients, and Providers by E. Fuller Torrey (Author) Since its first publication in 1983, Surviving Schizophrenia has become the standard reference book on the disease and has helped thousands of patients, their families and mental health professionals. In clear language, this much–praised and important book describes the nature, causes, symptoms, treatment and course of schizophrenia and also explores living with it from both the patient and the family's point of view. This new, completely updated fifth edition includes the latest research findings on what causes the disease as well as information about the newest drugs for treatment and answers to the questions most often asked by families, consumers and providers. |
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ABC News 20/20 Schizophrenia It's all in their minds: visions, voices, taunting, never ending, driving them crazy or worse. It's hard to imagine, but now, an amazing device lets you feel their pain. The technology lets you go inside the mind of a schizophrenic. See what they see. Hear what they hear. Using the technique of virtual reality, Janssen Pharmaceuticals has developed a device to stimulate the visual and auditory hallucinations of a schizophrenic patient. Dr. Timothy Johnson explores the world of people struggling with the voices within. This "20/20" show contains the following additional stories: Victim's Comp Windsheilds |
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The Complete Family Guide to Schizophrenia: Helping Your Loved One Get the Most Out of Life by Kim T. Mueser PhD (Author), Susan Gingerich MSW (Author) Will the person you love ever get better? Chances are you've grappled with the question. With care and support from their families, people with schizophrenia can and do make vast improvements. Noted therapists Kim Mueser and Susan Gingerich deepen your understanding of the illness and cover a wide range of effective treatments. Based on decades of research and experience, they offer pragmatic suggestions for dealing with depression, psychosis, and other symptoms. They show you how to prioritize needs, resolve everyday problems, and encourage your loved one to set life goals. Plus, individual sections highlight special issues for parents, children, siblings, and partners. Whether you’re facing schizophrenia for the first time or you’ve dealt with its impact for years, you’ll discover... |
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Schizophrenia For Dummies (For Dummies (Health & Fitness)) by Jerome Levine (Author), Irene S. Levine (Author) Practical tools for leading a happy, productive life Schizophrenia is a chronic, severe, and disabling mental disorder that afflicts one percent of the population, an estimated 2.5 million people in America alone. The firsthand advice in this reassuring guide will empower the families and caregivers of schizophrenia patients to take charge, offering expert advice on identifying the warning signs, choosing the right health professional, understanding currently available drugs and those on the horizon (as well as their side effects), and evaluating traditional and alternative therapies. |
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Me, Myself, and Them: A Firsthand Account of One Young Person's Experience with Schizophrenia (Adolescent Mental Health Initiative) by Kurt Snyder (Author), Raquel E. Gur M.D. (Author), Linda Wasmer Andrews (Author) During his second semester at college, Kurt Snyder became convinced that he was about to discover a fabulously important mathematical principle, spending hours lost in daydreams about numbers and symbols. In time, his thoughts took a darker turn, and he became preoccupied with the idea that cars were following him, or that strangers wanted to harm him. Kurt's mind had been hijacked by schizophrenia, a severe mental disorder that typically strikes during the late teen or young adult years. In Me, Myself, and Them, Kurt, now an adult, looks back from the vantage point of recovery and eloquently describes the debilitating changes in thoughts and perceptions that took hold of his life during his teens and twenties. As a memoir, this book is remarkable for its unvarnished look at the... |
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Recovered, Not Cured: A Journey Through Schizophrenia by Richard McLean (Author) This very personal exploration of schizophrenia explores each stage, from the early signs and reactions from friends and family to seeking help and the challenges of recovery. McLean bravely shares his paranoid delusions and offers both a verbal and a visual experience by including digital artwork he created to help objectify and control his impulses and fears. As McLean relates his experiences step by step, issues of sexuality, identity, and drug abuse are discussed, along with the overarching issues relating to mental health and the medical profession. Messages from online posters who either have suffered from mental illness or have cared for the mentally ill are included throughout, adding more perspectives to the author's personal experiences. This powerful combination of words and... |
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Getting Your Life Back Together When You Have Schizophrenia by Roberta Temes (Author) |
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Understanding Mental Illness and Schizophrenia (Home Use) Part of the award winning public television series Healthy Body/Healthy Mind. Mental Illnesses are complex diseases of the brain affecting thoughts, moods, and coping ability. There are many diseases you can see, feel and understand, but there are others that aren't as easy to comprehend. Education and compassion are key. Untreated mental illness costs Americans more than 100 billion dollars each year. Fear of Mental Illness and the lack of understanding prevent millions of people from seeking much needed treatment. Meet some of these people in this program. This product is manufactured on demand using DVD-R recordable media. Amazon.com's standard return policy will apply. |
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