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£11.5m for new structural proteomics research programmes
June 17, 2004
BBSRC has announced two new research programmes that together will receive £11.5m under the Structural Proteomics of Rational Targets Initiative (SPoRT). The Membrane Protein Structure Initiative (MPSI), a consortium of experienced membrane research groups at universities and institutes across the UK and led by the University of Glasgow, has been awarded over £6.8m. MPSI aims to develop strategies for the efficient production, crystallisation and structure determination of proteins that are located in the membranes of cells. Membrane proteins provide a range of functions that are essential for a healthy cell. Over 30 per cent of human genes produce membrane proteins and more than half of the drugs in current use act on membrane proteins so they are prime targets for structural studies despite being particularly difficult to determine.
The Structural Proteomics Facility, established by the Universities of Dundee, Glasgow, St Andrews and Warwick, will receive over £4.6m to fund an inclusive and multidisciplinary scientific programme. The programme aims apply high throughput methods to carefully selected microbial proteins, including those involved in natural product synthesis (many of the drugs used today are derived from natural products), enzymes which are required by microbes to cause disease, and proteins involved in the life cycle of viruses. All of this information will be important in understanding and combating pathogenic micro-organisms and developing novel applications.
BBSRC Chief Executive, Professor Julia Goodfellow said, 'The sequencing of a large number of genomes has provided us with a wealth of information but has raised many challenging questions about the function of proteins within cells. These are exciting programmes aimed at understanding the function of important groups of proteins at the molecular level.'
Biotechnology and Biological Sciences Research Council (BBSRC)
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Scientific Explorer's Mind Blowing Science Kit for Young Scientists
by Scientific Explorer
Mind blowing experiments to delight and educate young scientists! Erupt a color changing volcano. Mix up magic ooze with a mind of its own. Play with sand that never gets wet. Mix safe chemicals and watch colors change before your eyes. You'll amaze yourself and your friends as you explore the science behind these truly remarkable reactions.
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The Everything Kids' Science Experiments Book: Boil Ice, Float Water, Measure Gravity-Challenge the World Around You! (Everything Kids Series)
by Tom Robinson (Author)
Science has never been so easy - or so much fun! With The Everything Kids' Science Experiments Book, all you need to do is gather a few household items and you can recreate dozens of mind-blowing, kid-tested science experiments. High school science teach Tom Robinson shows you how to expand your scientific horizons - from biology to chemistry to physics to outer space. You'll discover answers to questions like: Is it possible to blow up a balloon without actually blowing into it? What is inside coins? Can a magnet ever be "turned off"? Do toilets always flush in the same direction? Can a swimming pool be cleaned with just the breath of one person? Get ready to enter the laboratory and learn how to conduct cool experiments, understand scientific terms...
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Scientific Explorer's Disgusting Science - A Kit for Studying the Science of Revolting Things
by Scientific Explorer
Grow your own friendly germs and fuzzy molds. Mix up a batch of coagulating fake blood. Even make a stinky intestine. learn the science behind unmentionable bodily functions while doing some truly NASTY Experiments. Ages 8+
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The Science Book: Everything You Need to Know About the World and How It Works (National Geographic)
by National Geographic (Author), Marshall Brain (Foreword)
A delight for the casual reader, yet so complete and wide-ranging that science buffs and students will welcome it, The Science Book encapsulates centuries of scientific thought in one richly illustrated volume. Natural phenomena, revolutionary inventions, and the most up-to-date investigations are explained in detailed text, and 2,000 vivid illustrationsincluding 3-D graphics and pictogramsmake the information even more accessible and amazing to discover.
The Science Book offers both a general overview of topics for the browsing reader and more specific information for those seeking deeper insight into a particular subject. Six major sections, ranging from the universe and planet Earth to biology, chemistry, physics, and mathematics, encompass everything from microscopic life...
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Scientific Explorer's The Magic Science Wizard's Kit
by Scientific Explorer
Cast real smoke from your fingertips, make a wizard wand, and whip up color-changing potions in your test tube laboratory. Also included are laminated cards with wizard facts, an instruction booklet with 11 activities, lab equipment, and mysterious wizard powders that will mix together to mystify you!
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Magic School Bus Journey into the Human Body Science Kit
by Young Scientist Club
The Magic School Bus and Ms. Frizzle take Young Scientists on a wild ride into the human body with these breathtaking experiments. Young Scientists bend bones, make joints, map taste buds, expand lungs, build a stethoscope, measure lung capacities and heart rates, perform the iodine starch test, spin glitter, simulate synovial fluid, create a human body poster, and much, much more! This exciting kit includes a life-size poster with eight sheets of body part stickers. So put on your seat belts, students, and get ready to discover The Human Body!
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The Complete Book of Science, Grades 5-6
by School Specialty Publishing (Author)
The Complete Book of Science for grades 5 to 6 teaches children important science skills! Children complete a variety of exercises that help them develop a number of skills in this 352 page workbook. Including a complete answer key this workbook features a user-friendly format perfect for browsing, research, and review. Over 4 million in print! The best-selling Complete Book series offers a full complement of instruction, activities, and information about a single topic or subject area. Containing over 30 titles and encompassing preschool to grade 8 this series helps children succeed in every subject area! ...
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Scientific Explorer's Tasty Science Chemistry in the Kitchen Kit
by Scientific Explorer
Who knew science could taste so good? With this kit, you’ll whip up cupcakes, cookies, candy, and more—all in the name of science! Learn what makes cakes rise, candy crystallize, and more real chemistry happen in the kitchen. Tasty Science is packed with ingredients, recipes, activity cards, a test tube laboratory, and lots more to explore the science of taste.
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What Is the World Made Of? All About Solids, Liquids, and Gases (Let's-Read-and-Find-Out Science, Stage 2)
by Kathleen Weidner Zoehfeld (Author), Paul Meisel (Author)
Did you ever walk through a wall? Drink a glass of blocks? Have you ever played with a lemonade doll, or put on milk for socks? This latest addition to the Let's-Read-and-Find-Out Science series introduces the youngest readers to an important science concept: the differences between solids, liquids, and gases. Any child who wants to know why he can't walk through a wall will enjoy Kathleen Zoehfeld's simple text and Paul Meisel's playful illustrations.
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Scientific Explorer's Spa Science Chemistry Kit
by Scientific Explorer
Whip your bath into a frothy fizzing sea of color and fragrance. Make colorful, fragrant bath gels, bath fizzers, spa lotion, bath balm, a face mask, and shampoo. Mix colors and fragrances to creat your own product line with secret and exclusive mixtures. Explore the science of gels, fragrance and fizzers.
Mixing fragrances in the bathtub is a delight for both girls and boys. It’s one of the best ways to introduce them to the fun of science. Kids will spend hours in the tub with this kit mixing ingredients to make foaming frothing baths and smelling potions and conducting science experiments to see how scents affect our alertness, moods and memories. Comparing the responses of siblings, parents and friends makes this a shared adventure the entire family will enjoy
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