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Zinc can help in the treatment of pneumonia (pp 1683)
May 19, 2004The addition of zinc to standard antimicrobial treatment may accelerate recovery from pneumonia, say researchers in this week's issue of THE LANCET.
Pneumonia is a leading cause of mortality and morbidity in children less than five years old. Zinc is reported to prevent pneumonia, and to prevent and treat diarrhoea, and it may boost the body's immune response to infection.
W Abdullah Brooks and colleagues from the International Centre for Diarrhoeal Disease Research, Bangladesh, investigated whether zinc would help children between 2 and 23 months old with severe pneumonia. 270 children were randomly assigned to receive 20 mg zinc per day, or a placebo, in addition to standard hospital antibiotics.
Children given zinc recovered from severe pneumonia an average of one day earlier than did those given placebo, and their average stay in hospital was one day shorter. The zinc supplement was safe and well tolerated. Since a course of zinc treatment costs only US$0"˘15, and one day in the study hospital costs US$25, the potential cost savings are substantial.
Dr Brooks comments: "The effects on treatment failure are striking, have significant implications for reduction of antimicrobial resistance by decreasing multiple antibiotic exposures, and could help reduce complications and death in situations where second line drugs are not available."
Lancet
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Scientists isolate genes that made 1918 flu lethal
By mixing and matching a contemporary flu virus with the "Spanish flu" - a virus that killed between 20 and 50 million people 90 years ago in history's most devastating outbreak of infectious disease - researchers have identified a set of three genes that helped underpin the extraordinary virulence of the 1918 virus.
Mayo Clinic study finds increased risk of pneumococcal disease in asthma patients
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Promising results from 2 trials highlighting pomalidomide presented at ASH
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Gene therapy effective treatment against gum disease
Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease, the leading cause of tooth loss in adults.
Lenalidomide safe as single therapy for elderly CLL patients
The oral medication lenalidomide is safe and well-tolerated for elderly patients with chronic lymphocytic leukemia, a group without a well-defined frontline therapy for their disease, researchers from The University of Texas M. D. Anderson Cancer Center reported today at the 50th annual meeting of the American Society of Hematology.
Common cold virus came from birds
A virus that causes cold-like symptoms in humans originated in birds and may have crossed the species barrier around 200 years ago, according to an article published in the December issue of the Journal of General Virology. Scientists hope their findings will help us understand how potentially deadly viruses emerge in humans.
Hospital visits for respiratory illnesses spiked during Southern California wildfires
Raging wildfires that engulfed Southern California earlier this decade not only destroyed neighborhoods laying in their path, they also caused significant health problems for many who lived outside the fires' reach.
Friendly bacteria reduce hospital infections
A probiotic bacterium, Lactobacillus plantarum 299, has been used to out-compete the dangerous bacteria that cause respiratory illness in ventilated patients.
Pakistan introduces vaccine to prevent top child killer
This month, Pakistan is introducing a new combination vaccine that will protect its children against the bacterium Haemophilus influenzae type b (Hib) and four other common childhood diseases.
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