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Cell Biology News Stories, Current Cell Biology News Events, Discoveries and Articles
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Cell Biology News Stories
Current Cell Biology News Events, Discoveries and Articles
Protein thought to promote cancer instead functions as a tumor suppressor, researchers report
A protein previously thought to promote colorectal cancer instead suppresses the growth of human cancer cells in culture, researchers at UT Southwestern Medical Center have found. (2008-07-08)

UT Southwestern researchers identify new targets for RNAs that regulate genes
Tiny strands of genetic material called RNA - a chemical cousin of DNA - are emerging as major players in gene regulation, the process inside cells that drives all biology and that scientists seek to control in order to fight disease. (2008-07-07)

Alzheimer's disease as a case of brake failure?
Rutgers researcher Karl Herrup and colleagues at Case Western Reserve University have discovered that a protein that suppresses cell division in brain cells effectively "puts the brakes" on the dementia that comes with Alzheimer's disease (AD). When the brakes fail, dementia results. (2008-06-25)

Refusal of suicide order: Why tumor cells become resistant
Cells with irreparable DNA damage normally induce programmed cell death, or apoptosis. However, this mechanism often fails in tumor cells so that transformed cells are able to multiply and spread throughout the body. (2008-06-24)

Understanding the migration of cancer cells
Lamellipodia are veil-shaped protrusions of the plasma membrane, that can turn into upward-curled ruffles if they fail to adhere to the substrate. (2008-06-23)

Penn researchers find key developmental pathway activates lung stem cells
Researchers from the University of Pennsylvania School of Medicine found that the activation of a molecular pathway important in stem cell and developmental biology leads to an increase in lung stem cells. Harnessing this knowledge could help develop therapies for lung-tissue repair after injury or disease. (2008-06-18)

EuroDYNA takes lid off the genome
European researchers have made significant progress unravelling how genes are governed and why this sometimes goes wrong in disease. (2008-06-16)

Centromeres cross over, a lot
Recombination at centromeres is higher than anywhere else on the chromosome, even though methyltransferases do their best to prevent it, say Jaco et al., as published in the June 16 issue of the Journal of Cell Biology. (2008-06-13)

'Intrabody' can mop up mutant protein in Huntington's disease model
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" against huntingtin, the protein whose mutant forms poison the brain cells of people with Huntington's. (2008-05-27)

OHSU Discovery May Lead to Early Cancer Detection
OHSU pancreatic cancer expert Brett Sheppard, M.D., and colleagues in the OHSU Oregon Stem Cell Center, have developed antibodies that recognize pancreatic cancer; Sheppard is presenting these findings this week during Digestive Disease Week in San Diego. (2008-05-23)



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