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Vitamin B3 reduces Alzheimer's symptoms, lesions
An over-the-counter vitamin in high doses prevented memory loss in mice with Alzheimer's disease, and UC Irvine scientists now are conducting a clinical trial to determine its effect in humans.   view more (2008-11-05)

3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually.   view more (2008-10-29)

Study findings help EMS respond to cardiac arrest emergencies more safely and efficiently
When cardiac arrest patients cannot successfully be resuscitated by emergency medical services in the field, lifesaving attempts to race them to a nearby hospital via ambulance often prove to be futile.   view more (2008-09-24)

Tracking Down the Menace in Mexico City Smog
A new report by scientists who are part of the international MILAGRO Campaign indicates that some of the most harmful air pollution in Mexico City may not come from motor vehicles but instead originates with industrial sources - and that the culprit may be garbage incineration.   view more (2008-09-08)

Data mining detects signs of Lou Gehrig's disease in gene carriers long before symptoms appear
Inspired by the use of microarray chips that look for gene combinations, psychologists are using "pattern array" software to spot movements in rats that might help them predict diseases such as Lou Gehrig's syndrome.   view more (2008-08-04)

Protein plays Jekyll and Hyde role in Lou Gehrig's disease
Amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease, is a fatal neurodegenerative disease caused by the death of motor neurons in the brain and spinal cord that control muscle movements from walking and swallowing to breathing. In a groundbreaking study this week in... view more (2008-07-29)

New study of gene evolution could lead to better understanding of neurodegenerative disease
Genetic evolution is strongly shaped by genes' efforts to prevent or tolerate errors in the production of proteins, scientists at The University of Texas at Austin and Harvard University have found.   view more (2008-07-25)

Researchers probe geographical ties to ALS cases among 1991 Gulf War veterans
Researchers from Duke University, the University of Cincinnati (UC) and the Durham Veterans Administration Medical Center are hoping to find a geographical pattern to help explain why 1991 Gulf War veterans contracted the fatal neurological disease amyotrophic lateral sclerosis (ALS) at twice the... view more (2008-07-22)

Umbilical cord blood cell transplants may help ALS patients
A study at the University of South Florida has shown that transplants of mononuclear human umbilical cord blood (MNChUCB) cells may help patients suffering from Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease.   view more (2008-06-25)

Lou Gehrig's protein found throughout brain, suggesting effects beyond motor neurons
Two years ago researchers at the University of Pennsylvania School of Medicine discovered that misfolded proteins called TDP-43 accumulated in the motor areas of the brains of patients with amyotropic lateral sclerosis (ALS), or Lou Gehrig's disease.   view more (2008-06-17)

UC San Diego Physicists Reveal Secrets of Newest Form of Carbon
Using one of the world's most powerful sources of man-made radiation, physicists from UC San Diego, Columbia University and Lawrence Berkeley National Laboratory have uncovered new secrets about the properties of graphene-a form of pure carbon that may one day replace the silicon in computers,... view more (2008-06-11)

Researchers block the transmission of malaria in animal tests
By disrupting the potassium channel of the malaria parasite, a team of researchers has been able to prevent the malaria parasites from forming in mosquitoes and has thereby broken the cycle of infection during recent animal tests.   view more (2008-06-10)

Genetics of ALS progression
An upcoming paper from Drs. Hidenori Ichijo and Hideki Nishitoh (The University of Tokyo) and colleagues lends new and valuable insight into the genetics of ALS.   view more (2008-06-02)

Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain
Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant... view more (2008-05-12)

Penn researchers find potential in yeast for selecting Lou Gehrig's disease drugs
Researchers from the University of Pennsylvania School of Medicine are developing a novel approach to screen for drugs to combat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, using yeast cells.   view more (2008-04-18)

Leaky blood vessels open up nerve cells to toxic assault in Lou Gehrig's disease
Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience.   view more (2008-04-08)

More genes for Lou Gehrig's disease identified, according to Penn researchers
In recent months a spate of mutations have been found in a disease protein called TDP-43 that is implicated in two neurodegenerative disorders: amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, and certain types of frontotemporal dementia (FTD). These mutations could... view more (2008-04-08)

Researchers Link 11 Genetic Variations to Type 2 Diabetes
Mathematicians at Michigan Technological University have developed powerful new tools for winnowing out the genes behind some of humanity's most intractable diseases.   view more (2008-04-02)

Researchers identify a gene responsible for cases of Lou Gehrig's disease
A team of Canadian and French researchers has identified a novel gene responsible for a significant fraction of ALS (sporadic amyotrophic lateral sclerosis) cases. ALS is commonly referred to as Lou Gehrig's disease, an incurable neuromuscular disorder that affects motor neurons and leads to... view more (2008-04-01)

Hope among patients with ALS may take a variety of forms
Sustaining hope in the face of a chronic, debilitating illness such as amyotrophic lateral sclerosis (ALS) should be a goal of palliative care and can take many forms, representing a continuum from focusing on the self to concern for others.   view more (2008-03-28)

Motor neuron disease and toxic substances: Possible link?
Motor neuron disease is a rare, devastating illness in which nerve cells that carry brain signals to muscles gradually deteriorate. One form of it, Lou Gehrig's disease or ALS (amyotrophic lateral sclerosis), is familiar to the public in the lives of scientist Stephen Hawking and Morrie Schwartz,... view more (2008-03-24)

Medical College of Wisconsin discovery alters longstanding concept of fixed protein structure
The thousands of proteins found in nature are simply strings of amino acids, assembled by genes, and scientists have long believed that they automatically fold themselves into uniquely fixed, 3-dimensional shapes to fire the engine of life.   view more (2008-03-18)

Gene newly linked to inherited ALS may also play role in common dementia
Scientists at Washington University School of Medicine in St. Louis have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig's disease.   view more (2008-02-21)

Targeting astrocytes slows disease progression in ALS
In what the researchers say could be promising news in the quest to find a therapy to slow the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, scientists at the University of California, San Diego (UCSD) School of Medicine have shown that targeting neuronal support... view more (2008-02-04)

Mayo Clinic study unveils unprecedented method to predict ALS, Parkinson's disease
A new Mayo Clinic study details an unprecedented method to predict brain aging disorders such as amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease) and Parkinson's disease.   view more (2008-01-16)
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