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New Down syndrome treatment suggested by Stanford/Packard study in mice At birth, children with Down syndrome aren't developmentally delayed. But as they age, these kids fall behind. Memory deficits inherent in Down syndrome hinder learning, making it hard for the brain to collect experiences needed for normal cognitive development. view more (2009-11-19)
Developmental delay could stem from nicotinic receptor deletion The loss of a gene through deletion of genetic material on chromosome 15 is associated with significant abnormalities in learning and behavior, said a consortium of researchers led by Baylor College of Medicine (www.bcm.edu) in a report that appears online today in the journal Nature Genetics. view more (2009-11-09)
Risk of abnormally slow heart rate twice as high in those taking drugs to slow Alzheimer's People taking one of several drugs commonly prescribed to treat Alzheimer's disease are more likely to be hospitalized for a potentially serious condition called bradycardia than patients not taking these medications. view more (2009-10-02)
Promising new treatment for Alzheimer's suggested based on Hebrew University research Research carried out at the Hebrew University of Jerusalem has resulted in a promising approach to help treat Alzheimer's disease in a significant proportion of the population that suffers from a particularly rapid development of this disease. view more (2009-07-21)
Barrow researchers identify new brain receptor, possible target for Alzheimer's treatment Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer's disease. view more (2009-07-17)
Genes: An extra hurdle to quitting smoking during pregnancy? Researchers from the Peninsula Medical School and the University of Bristol, using data from the Avon Longitudinal Study of Parents and Children and the Exeter Family Study of Childhood Health, have identified a common genetic variant that explains why some women may find it more difficult to quit smoking during pregnancy. view more (2009-05-15)
Nicotine may have more profound impact than previously thought Nicotine isn't just addictive. It may also interfere with dozens of cellular interactions in the body, new Brown University research suggests. view more (2009-04-06)
Caltech researchers find tiny genetic change keeps nicotine from binding to muscle cells A tiny genetic mutation is the key to understanding why nicotine--which binds to brain receptors with such addictive potency--is virtually powerless in muscle cells that are studded with the same type of receptor. view more (2009-03-24)
Cholinesterase inhibitors reduce aggression, wandering and paranoia in Alzheimer's disease Cholinesterase inhibitors, used to treat cognitive symptoms of Alzheimer's disease, are also a safe and effective alternative therapy for the behavioral and psychological symptoms of dementia, according to a study that appears in the December 2008 edition of Clinical Interventions in Aging. view more (2008-12-10)
Bound by Attention: Bringing rats and humans together When picking through a basket of fruit, it doesn't seem very difficult to recognize a green pear from a green apple. This is easy, thanks to "feature binding"- a process by which our brain combines all of the specific features of an object and gives us a complete and unified picture of it. view more (2008-11-19)
Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system Genetically modifying a receptor found on the neurons that produce the neurotransmitter dopamine has given California Institute of Technology (Caltech) researchers a unique glimpse into the workings of the brain's dopamine system--as well as a new target for treating diseases that result from either too much or too little of this critical... view more... (2008-10-15)
Do 'light' cigarettes deliver less nicotine to the brain than regular cigarettes? For decades now, cigarette makers have marketed so-called light cigarettes - which contain less nicotine than regular smokes - with the implication that they are less harmful to smokers' health. A new UCLA study shows, however, that they deliver nearly as much nicotine to the brain. view more (2008-09-29)
Researcher working on destruction of chemical weapons America's war on terror includes fighting the dark side of deadly chemical agents, and Texas A&M University chemist Dr. Frank Raushel is helping with the fight by developing an enzyme that might neutralize one such chemical agent, the organophosphates. view more (2008-09-25)
Researchers block damage to fetal brain following maternal alcohol consumption In a study on fetal alcohol syndrome, researchers were able to prevent the damage that alcohol causes to cells in a key area of the fetal brain by blocking acid sensitive potassium channels and preventing the acidic environment that alcohol produces. view more (2008-08-11)
Commonly used medications associated with impaired physical function in older adults Older adults who take drugs designed to block the neurotransmitter acetylcholine - including common medications for incontinence, high blood pressure and allergies - are more likely to be dependent in one or more activities of daily living and to walk slower, according to new findings from researchers at Wake Forest University School of Medicine... view more... (2008-05-05)
Dual treatment of incontinence and dementia associated with functional decline Older nursing home residents who took medications for dementia and incontinence at the same time had a 50 percent faster decline in function than those who were being treated only for dementia, according to a study from researchers at Wake Forest University School of Medicine and colleagues. view more (2008-05-01)
Researchers 'see' structure of open nicotinic acetylcholine ion channels The neurotransmitter acetylcholine is an essential chemical communicator, carrying impulses from neurons to skeletal muscle cells and many parts of the nervous system. view more (2008-04-08)
Researchers ID gene linked to lung cancer Researchers at Johns Hopkins, as part of a large, multi-institutional study, have found one gene variant that is linked to an increased risk of lung cancer. The study will be published in the April 3 issue of Nature Genetics. view more (2008-04-03)
Memantine and Alzheimer's disease In a study published this month in the Journal of Alzheimer's Disease, researchers from the University of Aberdeen report that the drug memantine, used for the treatment of Alzheimer's disease and praised as "the first and only representative of a new class of Alzheimer drugs" works in fact similar to other existing compounds, and is... view more... (2008-01-11)
Researchers uncover mechanisms of common inherited mental retardation Researchers at UT Southwestern Medical Center are uncovering how brain cells are affected in Fragile X syndrome, the most common cause of inherited mental retardation and the most common genetic cause of autism. view more (2008-01-09)
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