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Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system
Genetically modifying a receptor found on the neurons that produce the neurotransmitter dopamine has given California Institute of Technology (Caltech) researchers a unique glimpse into the workings of the brain's dopamine system--as well as a new target for treating diseases that result from... view more (2008-10-15)

1 sleepless night increases dopamine in the human brain
Just one night without sleep can increase the amount of the chemical dopamine in the human brain, according to new imaging research in the August 20 issue of The Journal of Neuroscience.   view more (2008-08-20)

N.Y. Research Team Discovers How Antidepressants and Cocaine Interact with Brain Cell Targets
In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies... view more (2008-07-30)

PET imaging focuses on medication's purported ability to improve mental performance
Concerned by the growing numbers of people using stimulant medications such as methylphenidate (MP)-either legally or illegally-to improve attention and focus, researchers used positron emission tomography (PET) imaging with the radiotracer fluorodeoxyglucose (FDG) to assess the effects of the drug... view more (2008-06-17)

Study finds link between amphetamine abuse and heart attacks in young adults
Young adults who abuse amphetamines may be at greater risk of suffering a heart attack, UT Southwestern Medical Center researchers have found.   view more (2008-06-04)

Animal research suggests new strategy for treating cocaine addiction
New research in monkeys suggests the feasibility of treating cocaine addiction with a "replacement" drug that mimics the effects of cocaine but has less potential for abuse - similar to the way nicotine and heroin addictions are treated.   view more (2008-04-07)

Chilean authors, publishing in Science, discover drug-craving brain region in rats
Chilean researchers have identified a region of the brain - the insular cortex - that plays a role in drug craving in amphetamine-addicted rats, according to a report published in the 26 October issue of the journal Science, published by the American Association for the Advancement of Science... view more (2007-10-26)

Insulin signaling and amphetamines
Abuse of psychostimulants such as amphetamine remains a serious public health concern. Amphetamines mediate their behavioral effects by stimulating dopaminergic signaling throughout reward circuits of the brain.   view more (2007-10-16)

Research Examines the Connection Between Substance Abuse and Violence
Approximately 50 percent of Americans over the age of 12 currently drink alcohol, according to a 2003 report by the Substance Abuse and Mental Health Services Administration.   view more (2007-10-10)

Brain-boosting pill alleviates post-chemotherapy fogginess
A drug described by some people as a "genius pill" for enhancing cognitive function provided relief to a small group of Rochester breast cancer survivors who were coping with a side effect known as "chemo-brain," according to a University of Rochester Medical Center study.   view more (2007-06-04)

Strokes may be associated with cocaine and amphetamine abuse
The use of stimulant drugs, including cocaine and amphetamines, may be linked to a higher risk for stroke, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.   view more (2007-04-03)

Prenatal cocaine's lasting cellular effects
Although the "crack baby" hysteria of the 1980s was greatly exaggerated, cocaine use during pregnancy can cause subtle but disabling cognitive impairments — attention deficits, learning disabilities and emotional problems.   view more (2007-01-15)

The G allele of the mu-opioid receptor gene is linked to craving for alcohol
The study of genes and their influence on alcohol consumption can operate on many different levels. Some studies examine how genes may interact with the environment, some look specifically at family history of alcohol dependence, and some zero in on "pieces" of genes and their influence... view more (2007-01-04)

New research identifies gene important for nicotine's effects on the brain
New research identifies an important gene that influences several aspects of nicotine-induced behaviors in the brain. The study, funded by National Institutes of Drug Abuse, was presented today at the American College of Neuropsychopharmacology's Annual Meeting.   view more (2006-12-06)

Ritalin packs punch by elevating norepinephrine, suppressing nerve signal transmissions
Methylphenidate (Ritalin) elevates norepinephrine levels in the brains of rats to help focus attention while suppressing nerve signal transmissions in the sensory pathways to make it easier to block out extraneous stimuli, a Philadelphia research team has found.   view more (2006-05-30)

New mechanism found for neurodegenerative effects of amphetamines in mice
University of Toronto researchers have discovered a new mechanism for the neurodegenerative effects of amphetamines.   view more (2006-04-06)

UCSF research pinpoints brain molecule's role in developing addiction
A molecule in the brain essential for wakefulness and appetite has been found to play a central role in strengthening the neuron connections that lead to addiction.   view more (2006-02-16)

Amphetamines reverse Parkinson's disease symptoms in mice
Amphetamines, including the drug popularly known as Ecstasy, can reverse the symptoms of Parkinson's disease in mice with an acute form of the condition, according to new research at Duke University Medical Center.   view more (2005-08-02)

Drugs, dyslexia and dumbing down
Drug use amongst men with learning disabilities, the link between dyslexia and psychopathology and students' perceptions of their intelligence are just some of the topics being discussed in a poster session presented at the British Psychological Society's Annual Conference at the University of... view more (2005-03-21)

The Effects of Ecstasy - It Takes Two to Tango in the Cell
Amphetamine derivatives like the life style drug Ecstasy cause the release of neurotransmitters through an ingenious interplay of cellular components: an enzyme causes two transport proteins of the same type to work in opposite directions. These new findings are in contrast to previous assumptions... view more (2005-02-21)

Leaves of the khat plant harbour a key to improving men's fertility
A chemical that occurs naturally in the leaves of an African plant could boost men's fertility, researchers told the 20th annual conference of the European Society of Human Reproduction and Embryology on Monday 28 June. Khat (Catha edulis) is a plant that has been cultivated for centuries in East... view more (2004-06-28)

Ecstasy alone can kill--and numbers of deaths continue to rise.
Research news in Human Psychopharmacology: Clinical and Experimental 22 September 2003: The world's largest study of ecstasy-related deaths discovered that one in six people who died after taking ecstasy had not taken any other drug. "This clears up the debate once and for all - ecstasy alone... view more (2003-09-22)

Sophisticated drugs detection
Police and customs around the world spend over $250 million a year on drug detection equipment. Despite efforts to develop new technologies, more than half of this money goes to one of the oldest drug detection systems in the world - the sniffer dog.   view more (2003-01-16)

Drugs to beat sleep
EMBARGOED UNTIL WEDNESDAY 30 OCTOBER 2002 19:00 GMT UK CONTACT - Claire Bowles, New Scientist Press Office, London: Tel: +44(0)20 7331 2751 or email claire.bowles@rbi.co.uk   view more (2002-10-30)

Fluoxetine: antidepressant and a possible new drug for the treatment of obesity
The Department of Nutrition and Bromatology of the Faculty of Pharmacy of Gasteiz, University of the Basque Country, is studying the action mechanism of fluoxetine in genetically fattened rats (Zucker fa/fa). Due to fluoxetine, those rats eat 50 % less. Therefore, the bodies put on less weight and... view more (2002-07-30)
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