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Collagen VI may help protect the brain against Alzheimer's disease
Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta (Aβ) proteins, which are widely thought to cause Alzheimer's disease (AD).   view more (2009-01-06)

Brain starvation as we age appears to trigger Alzheimer's
A slow, chronic starvation of the brain as we age appears to be one of the major triggers of a biochemical process that causes some forms of Alzheimer's disease.   view more (2008-12-29)

Two cardiovascular proteins pose a double whammy in Alzheimer's
Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease.   view more (2008-12-22)

A special type of collagen may help protect the brain against Alzheimer's disease
Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta (Aβ ) proteins, which are widely thought to cause Alzheimer's disease (AD).   view more (2008-12-11)

Mutant proteins result in infectious prion disease in mice
A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals.   view more (2008-12-08)

New study identifies link between Alzheimer's disease biomarkers in healthy adults
The Netherlands -- A study published in the November issue of the Journal of Alzheimer's Disease provides an insight into normal, physiological levels and association between proteins involved in development of Alzheimer's disease.   view more (2008-12-02)

Red, red wine: How it fights Alzheimer's
Scientists call it the "French paradox" - a society that, despite consuming food high in cholesterol and saturated fats, has long had low death rates from heart disease.   view more (2008-11-21)

Pittsburgh Compound B finds Alzheimer's-associated plaques in symptom-free older adults
In the largest study of its kind, Pittsburgh Compound B, an imaging agent that could facilitate the early diagnosis of Alzheimer's disease, has been used to identify amyloid deposition in the brains of clinically older adults.   view more (2008-11-11)

Vitamin B3 reduces Alzheimer's symptoms, lesions
An over-the-counter vitamin in high doses prevented memory loss in mice with Alzheimer's disease, and UC Irvine scientists now are conducting a clinical trial to determine its effect in humans.   view more (2008-11-05)

A high-fat diet could promote the development of Alzheimer's
A team of Université Laval researchers has shown that the main neurological markers for Alzheimer's disease are exacerbated in the brains of mice fed a diet rich in animal fat and poor in omega-3s.   view more (2008-10-29)

Epilepsy drug may help Alzheimer's patients
A popular epilepsy drug may also be beneficial in patients with Alzheimer's disease (AD), according to a new study to be published on October 27 in the Journal of Experimental Medicine. The anti-seizure drug valproic acid improved memory and reduced brain lesions in mice with an AD-like disease.   view more (2008-10-27)

Common epilepsy drug could prevent and treat Alzheimer's disease
The team led by UBC Psychiatry Prof. Weihong Song, who is also the Jack Brown and Family Professor and Chair in Alzheimer's Disease at UBC, found that if Valproic Acid (VPA) is used as a treatment in early stages of AD memory deficit is reversed.   view more (2008-10-27)

JHU chemists devise self-assembling 'organic wires'
From pacemakers constructed of materials that so closely mimic human tissues that a patient's body can't discern the difference to devices that bypass injured spinal cords to restore movement to paralyzed limbs, the possibilities presented by organic electronics read like something from a science... view more (2008-10-24)

Researchers seeking to identify Alzheimer's risk focus on specific blood biomarker
A simple blood test to detect whether a person might develop Alzheimer's disease is within sight and could eventually help scientists in their quest toward reversing the disease's onset in those likely to develop the debilitating neurological condition.   view more (2008-09-09)

Rapid changes in key Alzheimer's protein described in humans
For the first time, researchers have described hour-by-hour changes in the amount of amyloid beta, a protein that is believed to play a key role in Alzheimer's disease, in the human brain.   view more (2008-08-29)

MIT zeroes in on Alzheimer's structures
MIT engineers report a new approach to identifying protein structures key to Alzheimer's disease, an important step toward the development of new drugs that could prevent such structures from forming.   view more (2008-08-22)

PET scans may help assess presence of brain plaques related to Alzheimer's disease
A type of positron emission tomography (PET) scanning may be useful in a non-invasive assessment of the formation of Alzheimer's disease-related plaques in the brain, according to small study posted online today that will appear in the October 2008 print issue of Archives of Neurology, one of the... view more (2008-08-12)

Alzheimer's disease patients show improvement in trial of new drug
A new drug has been shown to improve the brain function of people with early stage Alzheimer's disease and reduce a key protein associated with the disease in the spinal fluid, in a small study published today in the journal Lancet Neurology and presented at the 2008 Alzheimer's Association... view more (2008-07-30)

Neurotherapeutics presents special issue on new treatments for Alzheimer's disease
The editors of Neurotherapeutics are pleased and proud to announce their July issue, devoted to "Novel Therapeutics for Alzheimer's Disease."   view more (2008-07-25)

NIST membrane model may unlock secrets of early-stage Alzheimer's
Researchers at the National Institute of Standards and Technology (NIST) and three collaborating institutions are using a new laboratory model of the membrane surrounding neurons in the brain to study how a protein long suspected of a role in early-stage Alzheimer's disease actually impairs a... view more (2008-07-24)

Calcium may be the key to understanding Alzheimer's disease
Researchers at the University of Pennsylvania School of Medicine have shown that mutations in two proteins associated with familial Alzheimer's disease disrupt the flow of calcium ions within neurons. The two proteins, called PS1 and PS2 (presenilin 1 and 2), interact with a calcium release channel... view more (2008-07-21)

Scientists demonstrate means of reducing Alzheimer's-like plaques in fly brain
Neuroscientists at Cold Spring Harbor Laboratory (CSHL) are part of a collaboration that has succeeded in demonstrating that overexpression of an enzyme in the brain can reduce telltale deposits causally linked with Alzheimer's disease.   view more (2008-07-16)

Ionophore reverses Alzheimer's within days in mouse models
Scientists report a remarkable improvement in Alzheimer's transgenic mice following treatment with a new drug. The study, published by Cell Press in the July 10th issue of the journal Neuron, provides the first demonstration that an ionophore, a compound that transports metal ions across cell... view more (2008-07-10)

Can tomatoes carry the cure for Alzheimer's?
The humble tomato could be a suitable carrier for an oral vaccine against Alzheimer's disease, according to HyunSoon Kim from the Korea Research Institute of Bioscience and Biotechnology (KRIBB) in Korea and colleagues from Digital Biotech Inc. and the Department of Biological Science at Wonkwang... view more (2008-07-09)

The good and the bad of a potential Alzheimer's target
Research in fruit flies has shown that enhancing the production of a protein called neprilysin can reduce the formation of plaques and neuron death associated with Alzheimer's, at the expense of reducing the flies' lifespan.   view more (2008-06-30)

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