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Researchers identify new anti-tumor gene
Researchers from Virginia Commonwealth University have identified a new anti-tumor gene called SARI that can interact with and suppress a key protein that is overexpressed in 90 percent of human cancers. The discovery could one day lead to an effective gene therapy for cancer.   view more (2008-12-17)

Prostate cancer spurs new nerves
Prostate cancer - and perhaps other cancers - promotes the growth of new nerves and the branching axons that carry their messages, a finding associated with more aggressive tumors, said researchers from Baylor College of Medicine in the first report of the phenomenon that appears today in the... view more (2008-12-01)

Stopping germs from ganging up on humans
Keeping germs from cooperating can delay the evolution of drug resistance more effectively than killing germs one by one with traditional drugs such as antibiotics, according to new research from The University of Arizona in Tucson.   view more (2008-11-20)

Cancer drugs my build and not tear down blood vessels
Scientists have thought that one way to foil a tumor from generating blood vessels to feed its growth - a process called angiogenesis - was by creating drugs aimed at stopping a key vessel growth-promoting protein. But now the opposite seems to be true.   view more (2008-11-10)

Pazopanib shrinks lung cancers before surgery
Pazopanib, a new oral angiogenesis inhibitor, has demonstrated interesting activity in difficult to treat non-small-cell lung cancer, US researchers report.   view more (2008-09-17)

Joining forces against cancer
In cancer therapy, the best results are often achieved by combining treatments such as chemotherapy, radiotherapy and surgery.    view more (2008-09-17)

Gap junction protein vital to successful pregnancy, researchers find
Researchers studying a critical stage of pregnancy - implantation of the embryo in the uterus - have found a protein that is vital to the growth of new blood vessels that sustain the embryo. Without this protein, which is produced in higher quantities in the presence of estrogen, the embryo is... view more (2008-09-11)

Angiotensin inhibitors and receptor blockers linked to lower risk of nonmelanoma skin cancer
The use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) was associated with a reduced risk of basal cell or squamous cell skin cancers in U.S. veterans, researchers report in the August 26 online issue of the Journal of the National Cancer Institute.   view more (2008-08-27)

Cancer therapy: A role for MAPK inhibitors combined with mTORC1 inhibitors
Nearly a decade ago, while it was being tested as an immunosuppressive agent to prevent organ rejection in transplant patients, the drug rapamycin was also discovered to have anti-tumor properties. Since then, several rapamycin analogs known as mTOR (mammalian target of rapamycin) inhibitors have... view more (2008-08-22)

Drugs to inhibit blood vessel growth show promise in rat model of deadly brain tumor
In a landmark study, Medical College of Wisconsin researchers in Milwaukee report that drugs used to inhibit a specific fatty acid in rat brains with glioblastoma-like tumors not only reduced new blood vessel growth and tumor size dramatically, but also prolonged survival. The study is the featured... view more (2008-08-22)

Gladstone scientists identify single microRNA that controls blood vessel development
Scientists from the Gladstone Institute of Cardiovascular Disease (GICD) and UCSF have identified a key regulatory factor that controls development of the human vascular system, the extensive network of arteries, veins, and capillaries that allow blood to reach all tissues and organs.   view more (2008-08-12)

Vitamin A pushes breast cancer to form blood vessel cells
Researchers at Georgetown University Medical Center have discovered that vitamin A, when applied to breast cancer cells, turns on genes that can push stem cells embedded in a tumor to morph into endothelial cells. These cells can then build blood vessels to link up to the body's blood supply,... view more (2008-07-16)

New oral angiogenesis inhibitor offers potential nontoxic therapy for a wide range of cancers
The first oral, broad-spectrum angiogenesis inhibitor, specially formulated through nanotechnology, shows promising anticancer results in mice, report researchers from Children's Hospital Boston.   view more (2008-07-02)

Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis
A recent study conducted by three French CNRS (Centre National de la Recherche Scientifique) laboratories describes a new candidate anti-cancer drug, named HB-19.   view more (2008-06-18)

Complex Changes in the Brain's Vascular System Occur after Menopause
Many women experience menopausal changes in their body including hot flashes, moodiness and fatigue, but the changes they don't notice can be more dangerous.   view more (2008-06-17)

Fruits, vegetables and teas may protect smokers from lung cancer, UCLA researchers report
Tobacco smokers who eat three servings of fruits and vegetables per day and drink green or black tea may be protecting themselves from lung cancer, according to a first-of-its-kind study by UCLA cancer researchers.   view more (2008-05-29)

Drug fends off kidney cancer progression
New data from an international, multicenter Phase III clinical trial has found that the experimental targeted therapy everolimus (RAD001) significantly delays cancer progression in patients with metastatic kidney cancer whose disease had worsened on other treatments.   view more (2008-05-19)

New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene.   view more (2008-05-09)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist?
Angiogenesis, the growth of new blood vessels, is a central process in diverse physiological and pathological situations such as healing of wounds and traumas, cardiovascular disorders, inflammatory conditions such as rheumatoid arthritis, and in cancer growth.   view more (2008-04-23)

Human vascular system in mice
The formation of new blood vessels, or angiogenesis, is an Achilles' heel of tumor growth, because tumors depend on the supply of oxygen and nutrients for survival.   view more (2008-04-15)

Ingredient Found In Green Tea Significantly Inhibits Breast Cancer Growth In Female Mice
Green tea is high in the antioxidant EGCG (epigallocatechin-3- gallate) which helps prevent the body's cells from becoming damaged and prematurely aged.   view more (2008-04-08)

FSU researcher's 'mutant' proteins could lead to new treatment for heart disease
Heart damage due to blocked arteries remains the leading cause of disease and death in the Western world, but a Florida State University College of Medicine researcher is helping to open new pathways toward treating the problem.   view more (2008-03-25)

Radiologists use special MRI to identify brain cancer early
A special type of magnetic resonance imaging (MRI) can depict changes in blood volume in the brain that often precede cancerous transformation of brain tumors, according to a new study published in the April issue of the journal Radiology.   view more (2008-03-25)
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