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Can EP4 agonist alleviate gastric lesions?
Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding.   view more (2009-11-18)

Chemosensitivity of cancer cells depends on their protein dependency
Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. The study will be published online October 26, 2009 and in the November 2, 2009 print issue of the Journal of Cell Biology (JCB).   view more (2009-10-26)

Herbal tonic for radiotherapy
Antioxidant extracts of the leaves of the Gingko biloba tree may protect cells from radiation damage, according to a study published in the International Journal of Low Radiation.   view more (2009-10-20)

Metals could forge new cancer drug
Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds.   view more (2009-10-19)

Promising novel treatment for human cancer -- Chrysanthemum indicum extract
A series of studies have demonstrated that Chrysanthemum indicum possesses antimicrobial, antiinflammatory, immunomodulatory, and neuroprotective effects.   view more (2009-10-16)

New aging studies improving vaccine efficacy for the elderly
A new study from the Trudeau Institute in Saranac Lake, New York, demonstrates that immune system cells important for both pathogen resistance and vaccine efficacy live longer in older animals but because of this longevity acquire functional defects.   view more (2009-10-06)

Roles of S100A2 and p63 in the carcinogenesis of esophageal squamous cell carcinoma
As a member of the S100 family, S100A2 is considered a candidate tumor-suppressor gene. Recently, p63 gene, a new member of the p53 gene family, has been studied in the fields of tumorigenesis, cell apoptosis and tissue growth.   view more (2009-09-17)

Yes-associated protein: Early diagnosis of gastric carcinoma
Yes-associated protein (YAP) is a type of cellular adaptor protein and transcriptional co-activator.   view more (2009-09-16)

Prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases
Study shows prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases such as atherosclerosis, diabetes and neurodegeneration.   view more (2009-09-14)

Green tea component may help preserve stored platelets, tissues
In two separate studies, a major component in green tea, epigallocatechin-3-O-gallate (EGCG), has been found to help prolong the preservation of both stored blood platelets and cryopreserved skin tissues.   view more (2009-09-14)

PPAR-g agonists have potential therapeutic role in gastric carcinoma?
Recently, the potential of PPAR-γ as a target for the prevention and treatment of cancer has been widely studied.   view more (2009-08-27)

Hepatitis C virus channels efforts into cell survival
Researchers at the University of Leeds have discovered a previously unknown mechanism that allows the hepatitis C virus (HCV) to remain in the body for decades.   view more (2009-08-18)

Study supports DNA repair-blocker research in cancer therapy
Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells' DNA with potent drugs while simultaneously preventing the cells from repairing themselves.   view more (2009-08-18)

MRC scientists advance understanding of cell death
Medical Research Council (MRC) scientists have made an important advance in understanding the biological processes involved when cells are prompted to die.   view more (2009-08-14)

Life and death in the living brain
Like clockwork, brain regions in many songbird species expand and shrink seasonally in response to hormones. Now, for the first time, University of Washington neurobiologists have interrupted this natural "annual remodeling" of the brain and have shown that there is a direct link between the death of old neurons and their replacement by... view more... (2009-08-11)

EphA2-targeted therapy delivers chemo directly to ovarian cancer cells
With a novel therapeutic delivery system, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center has successfully targeted a protein that is over-expressed in ovarian cancer cells.   view more (2009-07-30)

Scientists track impact of DNA damage in the developing brain
Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion.   view more (2009-07-28)

Protein That Promotes Cancer Cell Growth Identified
Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues.   view more (2009-07-27)

Human cells secrete cancer-killing protein, UK study finds
Human cells are able to secrete a cancer-killing protein, scientists at the University of Kentucky's Markey Cancer Center have found.   view more (2009-07-24)

Critical link in cell death pathway revealed
The role of a protein called XIAP in the regulation of cell death has been identified by Walter and Eliza Hall Institute researchers and has led them to recommend caution when drugs called IAP inhibitors are used to treat cancer patients with underlying liver conditions.   view more (2009-07-23)
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