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Researchers Identify Genes That Increase Rheumatoid Arthritis Risk
Researchers in the United States and Sweden have identified a genetic region associated with increased risk of rheumatoid arthritis (RA), a chronic and debilitating inflammatory disease of the joints that affects an estimated 2.1 million Americans.   view more (2007-10-05)

FDA approves knee-injury device for humans
A new knee-surgery device investigated by University of Missouri-Columbia researchers that will help to repair meniscus tears, which were previously defined as irreparable, has been approved by the FDA for use in humans.   view more (2007-10-03)

'Jumping genes' could make for safer gene delivery system
To move a gene from point A to point B, scientists and gene therapists have two proven options: a virus, which can effectively ferry genes of interest into cells, and a plasmid, an engineered loop of DNA that can do the same thing, albeit usually only on a short-term basis.   view more (2007-09-27)

Genes in rheumatoid arthritis
A paper published this week in the open access journal PLoS Medicine provides strong evidence that one specific part of the genome is associated with rheumatoid arthritis.   view more (2007-09-18)

Methadone and systematic follow-up: the best solution for managing chronic pain
Approximately 30% of Canadians suffer daily from chronic pain. Patients may be affected differently depending on the intensity, but all chronic pain is debilitating and difficult to treat.   view more (2007-09-13)

The genes involved in rheumatoid arthritis identified
The human genome has now been thoroughly screened in the hunt for the genetic causes of rheumatoid arthritis. The results, which both confirms previous hypotheses and turn the spotlight on entirely new genes, are presented in two articles in the prestigious New England Journal of Medicine.   view more (2007-09-07)

Study Identifies Genetic Risk Factor for Rheumatoid Arthritis, Lupus
A genetic variation has been identified that increases the risk of two chronic, autoimmune inflammatory diseases: rheumatoid arthritis (RA) and systemic lupus erythematosus (lupus).   view more (2007-09-07)

Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
A blood cell known as a troublemaker for triggering the itch and inflammation in allergy attacks, the mast cell, can also calm down the flare-ups.   view more (2007-09-04)

Knee arthritis link to lung cancer
Arthritis of the knee may be the first sign of a type of lung cancer that is hard to treat in heavy smokers, suggests research published ahead of print in the Annals of the Rheumatic Diseases.   view more (2007-09-04)

New insights into common knee injuries
The sort of swelling that occurs when a joint is damaged by injury or degeneration is normally essential to the healing process, but when it comes to the knee, that inflammation can actually interfere with healing.   view more (2007-08-30)

Specific antagonism lowers blood pressure
High blood pressure (hypertension) is associated with an increased risk of heart attack and stroke, and the frequent use of drugs known as NSAIDs, for example to treat individuals with rheumatoid arthritis, can cause hypertension.   view more (2007-08-17)

Using coxibs and NSAIDs to treat osteoarthritis
A panel of arthritis research experts has recommended that coxibs and nonsteroidal anti-inflammatory drugs (NSAIDs) must remain a significant part of the tool kit used in treating osteoarthritis (OA).   view more (2007-08-13)

The UAB heads a European research project on proteases and pathological processes
A research group of the UAB Institute of Biotechnology and Biomedicine and the UAB Department of Biochemistry and Molecular Biology, directed by Francesc Xavier Avilés, is the coordinator of a European project aimed at studying proteases with fluorescent molecules that allow their monitoring... view more (2007-07-18)

Small molecules may explain psoriasis
A research team at the Swedish medical university Karolinska Institutet has shown for the time that microRNA, small RNA molecules, may play an important role in the development of inflammatory skin diseases such as psoriasis and atopic eczema.   view more (2007-07-12)

Common rheumatoid arthritis treatment shows potential for diabetes prevention
Far fewer rheumatoid arthritis patients treated with the drug hydroxychloroquine (HCQ) went on to develop diabetes compared to those who never took the drug.   view more (2007-07-11)

Anti-malarial drug may reduce risk of diabetes for patients with rheumatoid arthritis
Preliminary research suggests that use of the anti-malarial drug hydroxychloroquine may help reduce the risk of the development of diabetes in patients with rheumatoid arthritis   view more (2007-07-11)

Scientists Discover Role of Enzyme in DNA Repair
Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's... view more (2007-06-28)

Further legitimization of fibromyalgia as a true medical condition
Fibromyalgia, a chronic, widespread pain in muscles and soft tissues accompanied by fatigue, is a fairly common condition that does not manifest any structural damage in an organ.   view more (2007-06-26)

Longer term breast feeding protects mother from risk of developing rheumatoid arthritis
Breast feeding for a period of thirteen months or more has been shown to reduce the mother's the risk of developing rheumatoid arthritis (RA).   view more (2007-06-18)

First multinational study of Tocilizumab reports in
Nearly half (43.9%) of rheumatoid arthritis (RA) patients receiving tocilizumab 8mg/kg, in addition to ongoing methotrexate therapy experienced a 50% (ACR50) improvement in symptoms at 24 weeks and more than one fifth achieved a 70% symptom improvement.   view more (2007-06-18)

Increased alcohol intake associated with decreased risk of developing rheumatoid arthritis
New data presented today at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain, suggests that alcohol may protect against rheumatoid arthritis, with three units a week exhibiting protective effects and ten units a week being more protective still.   view more (2007-06-18)

Disability from long-term rheumatoid arthritis reduced with biologic treatment
New data demonstrating the safety and efficacy of Enbrel® (etanercept) in the treatment of rheumatoid arthritis (RA) patients over the long-term were presented today at the EULAR (European League Against Rheumatism) congress.   view more (2007-06-13)

Gabapentin Shown Effective for Fibromyalgia Pain
New research supported by the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) shows that the anticonvulsant medication gabapentin, which is used for certain types of seizures, can be an effective treatment for the pain and other symptoms... view more (2007-06-12)

Breakthrough developments in rheumatoid arthritis reported
Peter K. Gregersen, MD, stares at x-rays of hands, searching out the telltale signs of inflamed joints and wrists from his research subjects with rheumatoid arthritis.   view more (2007-06-11)

Largest ever study of genetics of common diseases published today
The Wellcome Trust Case Control Consortium, the largest ever study of the genetics behind common diseases such as diabetes, rheumatoid arthritis and coronary heart disease, today publishes its results in the journals Nature and Nature Genetics.   view more (2007-06-07)
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