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Studies link cancer, inflammatory disease
The biological processes underlying diseases such as rheumatoid arthritis and cancer are fundamentally linked, and should be linked in how they are treated with drugs, a series of MIT studies indicates.   view more (2006-04-06)

Wasabi's kick linked to single pain receptor
A single pain receptor is responsible for the kick delivered by garlic and mustard oil, which is the active ingredient in mustard and in the pungent green sushi condiment known as wasabi, according to a Yale School of Medicine study published this week in Cell.   view more (2006-03-27)

Mystery solved: Gold's power against autoimmune diseases defined
Gold compounds have been used for the treatment of rheumatoid arthritis and other autoimmune diseases for more than 75 years, but until now, how the metals work has been a mystery.   view more (2006-02-27)

Methotrexate treatment for rheumatoid arthritis effective the second time
A second course of methotrexate, the most commonly used drug to treat rheumatoid arthritis, is effective in nearly half of studied patients for whom a previous treatment with the drug was ineffective.   view more (2006-02-24)

Efficacy of glucosamine, chondroitin sulfate may depend on level of osteoarthritis pain
The popular dietary supplements glucosamine and chondroitin sulfate proved no better than a placebo in relieving osteoarthritis knee pain in most participants of a major national trial.   view more (2006-02-23)

Scientists Exploring Inflammation in Rheumatoid Arthritis Make Unexpected Discovery That One Day May Lead to New Treatments
What makes joints in people with rheumatoid arthritis, and related conditions like Lyme disease or lupus, so susceptible to attack by the body's immune system, leading to painful flare-ups and deterioration? The answer may surprise you.   view more (2006-02-16)

Radiologic signs more than double sensitivity of MRIs
Radiologists can make a more accurate preoperative diagnosis of damage to knee cartilage by using four radiologic 'signs', a recent study found.   view more (2006-02-13)

Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha
Anti-malarial drugs are most effective in people with lupus who are genetically predisposed to high levels of tumour necrosis factor alpha and low levels of the cytokine IL-10.   view more (2006-02-13)

Preventing toxic side effects of inflammatory disease therapy
Researchers at the University of California, San Diego (UCSD) School of Medicine have developed a mouse model that could help scientists develop better drugs to fight autoimmune and inflammatory disorders such as multiple sclerosis and rheumatoid arthritis.   view more (2006-02-09)

Sydney scientists discover and license breakthrough anti-inflammatory treatment
Scientists from the Garvan Institute of Medical Research have developed what could be the next big blockbuster treatment for inflammatory diseases such as rheumatoid arthritis and asthma.   view more (2006-02-08)

Prescription painkillers effective in patients with dormant inflammatory bowel disease
According to two studies published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, prescription painkillers are effective in easing the pain of patients with dormant inflammatory bowel disease (IBD) and are not likely to cause symptom... view more (2006-02-03)

Hope for arthritis stems from within
Leeds bioengineers have developed an innovative technique for cartilage repair combining the self-healing powers of the body with stem cell science to help young people avoid debilitating knee problems and give hope to arthritis sufferers.   view more (2006-01-31)

Researchers map of genetic variations implicated in disease
Sequence differences in less than 0.2% of the 3-billion-base human genome play a vital role in a bewildering variety of human disease.   view more (2006-01-27)

'Vioxx like' drugs may still be best option for arthritis, write scientists
Scientists believe that despite the current concerns around anti-inflammatory drugs like Vioxx, they may still be the best option for treating some forms of arthritis.   view more (2006-01-19)

Infection-fighting protein could be key to autoimmune disease, say U-M scientists
Scientists at the University of Michigan Medical School have discovered that a protein called cryopyrin responds to invading bacteria by triggering the activation of a powerful inflammatory molecule called IL-1beta, which signals the immune system to attack pathogens and induces fever to protect... view more (2006-01-12)

New Treatment Promising For Ulcerative Colitis Sufferers
For people with the chronic disease ulcerative colitis, life can be limited to few social functions and trips away from home.   view more (2006-01-04)

Polymorphism and antibodies associated with highly increased risk of rheumatoid arthritis
People who have a specific genetic variant of the PTPN22 gene and test positive for antibodies against cyclic citrullinated peptide are much more at risk of developing rheumatoid arthritis than people who only have one of these markers.   view more (2005-12-22)

UQ scientists break new ground in fight against infection & chronic disease
University of Queensland (UQ) researchers are on track to develop new treatments for acute infections, chronic inflammatory diseases and cancer.   view more (2005-11-30)

MabThera - A unique approach providing lasting benefits for patients with rheumatoid arthritis
Roche today announced positive results of the Phase III REFLEX study, evaluating the efficacy and safety of MabThera in patients with rheumatoid arthritis (RA), who have had an inadequate response to anti-TNF biologic therapy.   view more (2005-11-17)

Study uncovers potential biomarker for lupus atherosclerosis
A certain form of the normally "good" high density lipoprotein (HDL) cholesterol linked to cardiovascular health plays a counterproductive role in people with systemic lupus erythematosus (SLE) and rheumatoid arthritis.   view more (2005-11-16)

Rheumatic disease increases risks in pregnancy, Stanford study finds
The first nationwide study of pregnancy outcomes in women with rheumatic disease confirms that they experience greater pregnancy risks and longer hospital stays than the average pregnant woman.   view more (2005-11-15)

Mayo researchers lead team that discovers role of dendritic cells in childhood autoimmune disease
Mayo Clinic researchers, working with colleagues at the University of Minnesota and University of Pittsburgh, are the first to describe a new role for a specialized cell of the immune system in children suffering from a rare muscle-damaging disease known as juvenile dermatomyositis (JDM).   view more (2005-11-14)

Fc gamma receptor gene variants associated with rheumatoid arthritis
People with a specific combination of variants of two genes, encoding two different receptors for the antibody Fc gamma, are three times more likely to develop rheumatoid arthritis than individuals with different variant combinations.   view more (2005-11-10)

Resetting epigenetic code could aid lupus patients
Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment.   view more (2005-11-08)

Contradictory immune responses explain different therapeutic effects in rheumatoid arthritis
Using a humanized mouse model that mimics the effects of human rheumatoid arthritis (RA), researchers have discovered that protein growth factors called cytokines in the immune system have both pro- and anti-inflammatory responses to RA.   view more (2005-11-07)
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