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How the 100th protein structure solved at Diamond impacts our understanding of how insects smell
New research announced today, Wednesday 30th September, by a team of leading scientists working with the UK's national Synchrotron, Diamond Light Source, could have a significant impact on the development and refinement of new eco-friendly pest control methods for worldwide agriculture. view more (2009-09-30)
Scripps Research scientists find early evolution maximized the 'spellchecking' of protein sequences
As letters of the alphabet spell out words, when amino acids are linked to one another in a particular order they "spell out" proteins. view more (2009-08-07)
MIT: Extending the shelf life of antibody drugs
A new computer model developed at MIT can help solve a problem that has plagued drug companies trying to develop promising new treatments made of antibodies: Such drugs have a relatively short shelf life because they tend to clump together, rendering them ineffective. view more (2009-06-30)
Discovery of the cell's water gate may lead to new cancer drugs
The flow of water into and out from the cell may play a crucial role in several types of cancer. Scientists at the University of Gothenburg have now found the gate that regulates the flow of water into yeast cells. view more (2009-06-17)
New study reveals structure of the HIV protein shell
New research by scientists at The Scripps Research Institute and other institutions provides a close-up look at the cone-shaped shell that is the hallmark of human immunodeficiency virus (HIV), revealing how it is held together-and possible ways to break it apart. view more (2009-06-15)
New images may improve vaccine design for deadly rotavirus
Howard Hughes Medical Institute researchers are reporting the first detailed molecular snapshots of a deadly gastrointestinal virus as it is caught in the grasp of an immune system molecule with the capacity to destroy it. view more (2009-06-12)
Research identifies 3-D structure of key nuclear pore building block
The genome of complex organisms is stashed away inside each cell's nucleus, a little like a sovereign shielded from the threatening world outside. view more (2009-06-08)
Scripps scientists find structure of a protein that makes cancer cells resistant to chemotherapy
A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells. The protein, called P-glycoprotein or P-gp for short, is one of the main reasons cancer cells are resistant to chemotherapy drugs. Understanding its structure may help scientists design... view more... (2009-03-27)
Antibody key to treating variant CJD, scientists find
Scientists at the University of Liverpool have determined the atomic structure of the 'binding' between a brain protein and an antibody that could be key to treating patients with diseases such as variant CJD. view more (2009-03-04)
Structural polymorphism of 441-residue Tau at single residue resolution
Worldwide almost 30 million suffer from Alzheimer's disease, an irreversible, neurodegenerative condition that is eventually fatal. view more (2009-02-17)
Groundbreaking study on complex movements of enzymes
A groundbreaking study has revealed in great detail how enzymes in the cell cooperate to make fat. These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs. view more (2009-02-12)
Structure of enzyme against chemical warfare agents determined
The enzyme DFPase from the squid Loligo vulgaris, is able to rapidly and efficiently detoxify chemical warfare agents such as Sarin, which was used in the Tokyo subway attacks in 1995. view more (2009-01-29)
Iowa State University researchers discover structure of key Ebola protein
Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus. view more (2009-01-13)
Dartmouth researchers find new protein function
A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division. view more (2009-01-09)
Properties of Unusual Virus Revealed in Researchers
A team of researchers from Penn State University and the University of Chicago has uncovered clues that may explain how and why a particular virus, called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The results, which are published in the current issue of the journal Molecular Cell, contribute... view more... (2008-12-09)
Crystallography reveals the 3-D structure of mammalian sperm receptor
Scientists at the Swedish medical university Karolinska Institutet have determined the first 3D structure of ZP3, a protein essential for the interaction between the mammalian egg coat and sperm. view more (2008-12-05)
New insight into the controls on a go-to enzyme
Scientists at St. Jude Children's Research Hospital have gained new insights into regulation of one of the body's enzyme workhorses called calpains. view more (2008-11-20)
Discovery offers new understanding of diabetes drug target
Scientists at the University of Leicester have published findings about a new advance in the study of major diabetes drug target. view more (2008-09-26)
Improved technique determines structure in membrane proteins
Understanding the form and function of certain proteins in the human body is becoming faster and easier, thanks to the work of researchers at the University of Illinois. view more (2008-08-18)
Newly described 'dragon' protein could be key to bird flu cure
Scientists and researchers have taken a big step closer to a cure for the most common strain of avian influenza, or "bird flu," the potential pandemic that has claimed more than 200 lives and infected nearly 400 people in 14 countries since it was identified in 2003. view more (2008-07-16)
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