Recent Crystallography Current Events | Crystallography News | 2
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Newly described 'dragon' protein could be key to bird flu cure
Scientists and researchers have taken a big step closer to a cure for the most common strain of avian influenza, or "bird flu," the potential pandemic that has claimed more than 200 lives and infected nearly 400 people in 14 countries since it was identified in 2003. view more (2008-07-16)
UCLA researchers clarify function of glucose transport molecule
Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells. view more (2008-07-07)
Double binding sites on tumor target may provide future combination therapy
Researchers from the University of Pennsylvania School of Medicine and colleagues at Merck Serono Research in Germany have found that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination therapy for certain types of cancer. view more (2008-04-09)
Findings reveal how dengue virus matures, becomes infectious
Biologists at Purdue University have determined why dengue virus particles undergo structural changes as they mature in host cells and how the changes are critical for enabling the virus to infect new host cells. view more (2008-03-28)
IUPUI scientists report first 3-D view of anti-cancer agent
Researchers from the Indiana University School of Medicine and the Purdue School of Science at Indiana University-Purdue University Indianapolis have created the first three-dimensional image of how a well-established chemotherapy agent targets and binds to DNA. view more (2008-03-19)
Poxvirus Potency Uncovered in New Atomic Map
Scientists at the University of Alabama at Birmingham (UAB) and Saint Louis University used X-ray crystallography to uncover new details about the infectious potency of poxviruses, furthering the understanding of how viral infections can subvert the body's immune system. view more (2008-02-04)
First Look at an Enzyme Target for Antibacterial and Cancer Drugs
The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication, and is a prime target of antibacterial and anticancer drugs. view more (2007-12-21)
Researchers solve first structure of a key to intact DNA inheritance
Researchers have solved the structure of a DNA-protein complex that is crucial in the spread of antibiotic resistance among bacteria. Knowing this structure also provides fundamental insight into how cells successfully divide into two new cells with intact DNA. view more (2007-12-21)
Potent Peptides Inhibit HIV Entry Into Cells
Based in part on protein structures determined at the National Synchrotron Light Source (NSLS) at the U.S. Department of Energy's Brookhaven National Laboratory, scientists at the University of Utah have developed new peptides that appear to be significantly more effective at blocking HIV's entry into cells than other drugs in their class. view more (2007-10-11)
Scientists learn structure of enzyme in unusual virus
Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses. view more (2007-09-18)
Toxic shock: immune system's anthrax link
Human immune proteins crucial for fighting cancer, viruses and bacterial infections belong to an ancient and lethal toxin family previously only found in bacteria, Australian researchers have found. view more (2007-08-24)
Malaria-resistant mosquitoes battle disease with 'molecular warhead'
A team led by UT Southwestern Medical Center researchers has discovered why some mosquitoes are resistant to malaria, a finding that may one day help fight a disease that afflicts and kills millions of people. view more (2007-07-09)
Discovery about obesity drug helping scientists develop new cancer treatments
Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments. view more (2007-07-09)
Researchers Create Model of Cancer-Preventing Enzyme, Study How It Works
Proline dehydrogenase is important because it plays a role in apoptosis, the process of cell death, by enabling the creation of superoxide, a highly reactive electron-rich oxygen species. view more (2007-05-14)
RNA enzyme structure offers a glimpse into the origins of life
Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules. view more (2007-03-16)
Chemical switch triggers critical cell activities
The freeze-frame image of a molecular relay race, in which one enzyme passes off a protein like a baton to another enzyme, has solved a key mystery to how cells control some vital functions. view more (2007-01-17)
Molecular Anatomy of Influenza Virus Detailed
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health in Bethesda, Md., and colleagues at the University of Virginia in Charlottesville have succeeded in imaging, in unprecedented detail, the virus that causes influenza. view more (2007-01-02)
Study reveals molecular basis of botulism toxin's deadly activity
In the study, the scientists reveal the mysterious structural basis of the remarkably strong interaction that botulinum toxins form with nerve cells, a union so robust that a single toxin molecule can completely incapacitate a nerve cell. view more (2006-12-18)
Botulism study could lead to new vaccines and treatments to counter bioterrorist attacks
Of all the weapons in the bioterrorist arsenal, none is as potent as botulinum neurotoxin, which causes botulism-a potentially fatal disease with symptoms that include severe paralysis of the limbs and respiratory muscles. view more (2006-12-14)
Biologists probe the machinery of cellular protein factories
Proteins of all sizes and shapes do most of the work in living cells, and the DNA sequences in genes spell out the instructions for making those proteins. view more (2006-09-14)
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